Introduction
Materials and methods
Results
Survey
Number of centres following each strategy | ||||
---|---|---|---|---|
ASA monotherapy (N) | DAPT Clopidogrel (N) | DAPT Prasugrel (N) | DAPT Ticagrelor (N) | |
Continue: | 5 | – | – | – |
Discontinue: | ||||
1 day | – | – | – | – |
2 days | – | – | – | 1 |
3 days | 1 | – | – | – |
4 days | 1 | 1 | 1 | 1 |
3–5 days | 1 | – | – | – |
5 days | 2 | 1 | 3 | 5 |
5–7 days | – | – | – | 1 |
7 days | – | 1 | 2 | 1 |
7–10 days | 1 | 6 | 1 | – |
Registry
Characteristics |
N = 70
N (%) |
---|---|
Patient characteristics
| |
Male | 57 (81.4) |
Age, mean, (SD), years | 65.5 ± 10.1 |
Body mass index, mean, (SD) | 28.0 ± 3.2 |
Current smoker | 14 (20.3) |
Ex-smoker (>6 weeks) | 19 (27.5) |
Family history for CAD | 8 (12.1) |
Medical history
| |
Hypertension | 58 (82.9) |
Diabetes mellitus | 21 (30.0) |
Dyslipidaemia | 37 (52.9) |
Angina pectoris month prior to surgery* | 50 (71.4) |
TIA/Stroke | 6 (8.6) |
COPD | 6 (8.6) |
Chronic kidney disease (eGFR MDRD4 < 60 ml/min) | 3 (4.3) |
Peripheral arterial disease | 3 (4.3) |
Heart failure (NYHA class III or IV) | 9 (12.9) |
ACS | 39 (55.7) |
– MI | 34 (48.6) |
Prior PCI | 18 (26.1) |
– PCI + Stent | 11 (15.7) |
Prior CABG | 0 (0.0) |
Preoperative medication use
| |
Oral nitrates | 15 (21.4) |
Beta-blockers | 57 (81.4) |
ACE inhibitor | 38 (54.3) |
AT-II-antagonists | 17 (24.3) |
Diuretics | 18 (25.7) |
Statins and other lipid-lowering drugs | 67 (95.7) |
Oral antidiabetics | 16 (22.9) |
Insulin | 8 (11.4) |
Surgery
| |
Coronary artery disease | |
– One vessel | 10 (14.3) |
– Two vessel | 9 (12.9) |
– Three vessel | 51 (72.9) |
Timing | |
– Elective/planned | 66 (94.3) |
– Urgent | 2 (2.9) |
– Emergency | 2 (2.9) |
EuroScore (SD) | 3.2 ± 2.6 |
ASA monotherapy | DAPT clopidogrel | DAPT ticagrelor | |
---|---|---|---|
Preoperative
| |||
Continued | 21 | 1 | 6 |
Discontinued | 20 | 4 | 13 |
Days discontinued, median (IQR) | 6 (2) | 6 (3.5) | 5 (5.5) |
Postoperative
| |||
No restart | 0 | 2 | 10 |
Restart | 20 | 2 | 3 |
Days after CABG until restart, median (IQR) | 1 (0) | 2.5 (3) | 1 (2) |