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Gepubliceerd in: Journal of Autism and Developmental Disorders 1/2022

24-02-2021 | Original Paper

Perinatal Factors in Newborn Are Insidious Risk Factors for Childhood Autism Spectrum Disorders: A Population-based Study

Auteurs: Inn-Chi Lee, Yu-Hsun Wang, Jeng-Yuan Chiou, James Cheng-Chung Wei

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 1/2022

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Abstract

We analyzed claims data from the Taiwan National Health Insurance database, which contains data of 23.5 million Taiwan residents. We included children born after January 1, 2000 who had received a diagnosis of autism spectrum disorders (ASD). Patients who were not diagnosed with ASD were included in the control group. The ASD prevalence was 517 in 62,051 (0.83%) children. Neonatal jaundice, hypoglycemia, intrauterine growth retardation (IUGR), and craniofacial anomalies (CFA) differed significantly between the ASD and control groups. After logistic regressive analysis, the adjusted odds ratios of IUGR, CFA, neonatal hypoglycemia, and neonatal jaundice were 8.58, 7.37, 3.83, and 1.32, respectively. Those insidiously perinatal risk factors, namely CFA, IUGR, neonatal hypoglycemia, and neonatal jaundice, could increase the risk of ASD.
Literatuur
go back to reference Bejarano-Martin, A., Canal-Bedia, R., Magan-Maganto, M., Fernandez-Alvarez, C., Cilleros-Martin, M. V., Sanchez-Gomez, M. C., Posada de la Paz, M. (2019). Early Detection, Diagnosis and Intervention Services for Young Children with Autism Spectrum Disorder in the European Union (ASDEU): Family and Professional Perspectives. Journal of Autism and Developmental Disorders. https://​doi.​org/​ https://​doi.​org/​10.​1007/​s10803-019-04253-0 Bejarano-Martin, A., Canal-Bedia, R., Magan-Maganto, M., Fernandez-Alvarez, C., Cilleros-Martin, M. V., Sanchez-Gomez, M. C., Posada de la Paz, M. (2019). Early Detection, Diagnosis and Intervention Services for Young Children with Autism Spectrum Disorder in the European Union (ASDEU): Family and Professional Perspectives. Journal of Autism and Developmental Disorders. https://​doi.​org/​ https://​doi.​org/​10.​1007/​s10803-019-04253-0
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Metagegevens
Titel
Perinatal Factors in Newborn Are Insidious Risk Factors for Childhood Autism Spectrum Disorders: A Population-based Study
Auteurs
Inn-Chi Lee
Yu-Hsun Wang
Jeng-Yuan Chiou
James Cheng-Chung Wei
Publicatiedatum
24-02-2021
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 1/2022
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-021-04921-0