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19-02-2019 | Uitgave 7/2019 Open Access

Quality of Life Research 7/2019

Patterns, trends and methodological associations in the measurement and valuation of childhood health utilities

Tijdschrift:
Quality of Life Research > Uitgave 7/2019
Auteurs:
Joseph Kwon, Sung Wook Kim, Wendy J. Ungar, Kate Tsiplova, Jason Madan, Stavros Petrou
Belangrijke opmerkingen

Electronic supplementary material

The online version of this article (https://​doi.​org/​10.​1007/​s11136-019-02121-z) contains supplementary material, which is available to authorized users.

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Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Abstract

Purpose

To systematically assess patterns and temporal changes in the measurement and valuation of childhood health utilities and associations between methodological factors.

Methods

Studies reporting childhood health utilities using direct or indirect valuation methods, published by June 2017, were identified through PubMed, Embase, Web of Science, PsycINFO, EconLit, CINAHL, Cochrane Library and PEDE. The following were explored: patterns in tariff application; linear trends in numbers of studies/samples and paediatric cost–utility analyses (CUAs) and associations between them; changes in proportions of studies/samples within characteristic-based categories over pre-specified periods; impact of National Institute for Health and Care Excellence (NICE) guidance on primary UK research and associations between valuation method, age and methodological factors.

Results

335 studies with 3974 samples covering all ICD-10 chapters, 23 valuation methods, 12 respondent types and 42 countries were identified by systematic review. 34.0% of samples using indirect methods compatible with childhood applied childhood-derived tariffs. There was no association between numbers of studies/samples and numbers of CUAs. Compared to 1990–2008, 2009–June 2017 saw a significant fall in the proportion of studies using case series; significant compositional changes across ICD-10 chapters and significantly higher sample proportions using childhood-specific and adult-specific indirect valuation methods, and based on pre-adolescents, self-assessment, self-administration and experienced health states. NICE guidance was weakly effective in promoting reference methods. Associations between valuation method, age and methodological factors were significant.

Conclusion

1990–2017 witnessed significant changes in primary research on childhood health utilities. Health technology assessment agencies should note the equivocal effect of methodological guidance on primary research.

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Extra materiaal
Supplementary material 1 ONLINE RESOURCE Excel database containing information on all 3,974 sub-samples of health utilities and descriptors can be found online at http://childhoodutilities.wordpress.com. The website also contains the detailed search strategy and a guidance note for Excel navigation. (DOCX 162 KB)
11136_2019_2121_MOESM1_ESM.docx
Literatuur
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