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Gepubliceerd in: Journal of Autism and Developmental Disorders 11/2019

31-08-2019 | Original Paper

Patterns of Cerebellar Connectivity with Intrinsic Connectivity Networks in Autism Spectrum Disorders

Auteurs: Haley M. Bednarz, Rajesh K. Kana

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 11/2019

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Abstract

There is growing evidence of altered connectivity in autism spectrum disorders (ASD) between the cerebellum and cortex. Three intrinsic connectivity networks (ICNs) are especially important to cognitive processing in ASD: the default mode network (DMN), executive control network (ECN), and salience networks (SNs). The goal of this study was to compare resting-state functional connectivity between the cerebellum and the DMN, ECN, and SN in ASD and typically developing children (n = 74, ages 7–12 years). Children with ASD showed stronger connectivity between the ventral DMN and left cerebellar lobules I–IV. No meaningful relationships were observed between ICN-cerebellar functional connectivity and ASD symptoms. These results suggest that the cerebellum contributes to altered network connectivity in ASD.
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Metagegevens
Titel
Patterns of Cerebellar Connectivity with Intrinsic Connectivity Networks in Autism Spectrum Disorders
Auteurs
Haley M. Bednarz
Rajesh K. Kana
Publicatiedatum
31-08-2019
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 11/2019
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-019-04168-w

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