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Gepubliceerd in: Journal of Behavioral Medicine 6/2022

20-08-2022

Patient-caregiver dyads in pancreatic cancer: identification of patient and caregiver factors associated with caregiver well-being

Auteurs: Brent T. Xia, Amy K. Otto, Kelvin Allenson, Maria Kocab, Wenyi Fan, Qianxing Mo, Jason W. Denbo, Mokenge P. Malafa, Jennifer B. Permuth, Dae Won Kim, Jason B. Fleming, Maija Reblin, Pamela J. Hodul

Gepubliceerd in: Journal of Behavioral Medicine | Uitgave 6/2022

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Abstract

We aimed to examine the psychosocial well-being in the pancreas cancer patient-caregiver dyad, and determine patient and caregiver characteristics that predict caregiver distress. This was a cross-sectional, observational study. Demographics and caregiving characteristics were gathered from patients and caregivers. Caregivers completed validated instruments investigating anxiety, depression, perceived stress and caregiver burden. Over a period of eleven months, 128 patient-caregiver dyads were enrolled. Patient and caregiver distress scores were not associated with patient clinical disease burden. Patient distress was a significant predictor of concurrent caregiver distress, anxiety, depression, and perceived burden. Younger caregivers were also associated with higher caregiver anxiety and perceived burden. Additionally, number of caregiving activities and caregiver overall health status were predictors of concurrent caregiver depression and perceived stress. Certain pancreatic cancer patient and caregiver variables may negatively impact the well-being of caregivers. Future efforts should focus on development and implementation of comprehensive caregiver support programs for those at risk for psychosocial distress.
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Literatuur
go back to reference Allen, C. J., Yakoub, D., Macedo, F. I., Dosch, A. R., Brosch, J., Dudeja, V., Ayala, R., & Merchant, N. B. (2018). Long-term quality of life and gastrointestinal functional outcomes after pancreaticoduodenectomy. Annals of Surgery, 268, 657–664.CrossRefPubMed Allen, C. J., Yakoub, D., Macedo, F. I., Dosch, A. R., Brosch, J., Dudeja, V., Ayala, R., & Merchant, N. B. (2018). Long-term quality of life and gastrointestinal functional outcomes after pancreaticoduodenectomy. Annals of Surgery, 268, 657–664.CrossRefPubMed
go back to reference Andersen, B. L., Thornton, L. M., Shapiro, C. L., Farrar, W. B., Mundy, B. L., Yang, H. C., & Carson, W. E. (2010). Biobehavioral, immune, and health benefits following recurrence for psychological intervention participants. Clinical Cancer Research, 16, 3270–3278.CrossRefPubMedPubMedCentral Andersen, B. L., Thornton, L. M., Shapiro, C. L., Farrar, W. B., Mundy, B. L., Yang, H. C., & Carson, W. E. (2010). Biobehavioral, immune, and health benefits following recurrence for psychological intervention participants. Clinical Cancer Research, 16, 3270–3278.CrossRefPubMedPubMedCentral
go back to reference Andrews, S. C. (2001). Caregiver burden and symptom distress in people with cancer receiving hospice care. Oncology Nursing Forum, 28, 1469–1474.PubMed Andrews, S. C. (2001). Caregiver burden and symptom distress in people with cancer receiving hospice care. Oncology Nursing Forum, 28, 1469–1474.PubMed
go back to reference Bedard, M., Molloy, D. W., Squire, L., Dubois, S., Lever, J. A., & O’Donnell, M. (2001). The Zarit Burden Interview: A new short version and screening version. The Gerontologist, 41, 652–657.CrossRefPubMed Bedard, M., Molloy, D. W., Squire, L., Dubois, S., Lever, J. A., & O’Donnell, M. (2001). The Zarit Burden Interview: A new short version and screening version. The Gerontologist, 41, 652–657.CrossRefPubMed
go back to reference Cancer Facts and Figures 2022." American Cancer Society. Cancer Facts and Figures 2022." American Cancer Society.
go back to reference Cella, D., Choi, S. W., Condon, D. M., Schalet, B., Hays, R. D., Rothrock, N. E., Yount, S., Cook, K. F., Gershon, R. C., Amtmann, D., DeWalt, D. A., Pilkonis, P. A., Stone, A. A., Weinfurt, K., & Reeve, B. B. (2019). PROMIS((R)) Adult health profiles: efficient short-form measures of seven health domains. Value Health, 22, 537–544.CrossRefPubMedPubMedCentral Cella, D., Choi, S. W., Condon, D. M., Schalet, B., Hays, R. D., Rothrock, N. E., Yount, S., Cook, K. F., Gershon, R. C., Amtmann, D., DeWalt, D. A., Pilkonis, P. A., Stone, A. A., Weinfurt, K., & Reeve, B. B. (2019). PROMIS((R)) Adult health profiles: efficient short-form measures of seven health domains. Value Health, 22, 537–544.CrossRefPubMedPubMedCentral
go back to reference Cohen, S., Kamarck, T., & Mermelstein, R. (1983). A global measure of perceived stress. Journal of Health and Social Behavior, 24, 385–396.CrossRefPubMed Cohen, S., Kamarck, T., & Mermelstein, R. (1983). A global measure of perceived stress. Journal of Health and Social Behavior, 24, 385–396.CrossRefPubMed
go back to reference Collado, L., & Brownell, I. (2019). The crippling financial toxicity of cancer in the United States. Cancer Biology & Therapy, 20, 1301–1303.CrossRef Collado, L., & Brownell, I. (2019). The crippling financial toxicity of cancer in the United States. Cancer Biology & Therapy, 20, 1301–1303.CrossRef
go back to reference Conroy, T., Desseigne, F., Ychou, M., Bouché, O., Guimbaud, R., Bécouarn, Y., Adenis, A., Raoul, J. L., Gourgou-Bourgade, S., de la Fouchardière, C., & Bennouna, J. (2011). FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. New England Journal of Medicine, 364, 1817–1825.CrossRefPubMed Conroy, T., Desseigne, F., Ychou, M., Bouché, O., Guimbaud, R., Bécouarn, Y., Adenis, A., Raoul, J. L., Gourgou-Bourgade, S., de la Fouchardière, C., & Bennouna, J. (2011). FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. New England Journal of Medicine, 364, 1817–1825.CrossRefPubMed
go back to reference Deng, Y., Tu, H., Pierzynski, J. A., Miller, E. D., Gu, X., Huang, M., Chang, D. W., Ye, Y., Hildebrandt, M. A. T., Klein, A. P., Zhao, R., Lippman, S. M., & Wu, X. (2018). Determinants and prognostic value of quality of life in patients with pancreatic ductal adenocarcinoma. European Journal of Cancer, 92, 20–32.CrossRefPubMedPubMedCentral Deng, Y., Tu, H., Pierzynski, J. A., Miller, E. D., Gu, X., Huang, M., Chang, D. W., Ye, Y., Hildebrandt, M. A. T., Klein, A. P., Zhao, R., Lippman, S. M., & Wu, X. (2018). Determinants and prognostic value of quality of life in patients with pancreatic ductal adenocarcinoma. European Journal of Cancer, 92, 20–32.CrossRefPubMedPubMedCentral
go back to reference Dengso, K. E., Thomsen, T., Andersen, E. W., Hansen, C. P., Christensen, B. M., Hillingso, J., & Dalton, S. O. (2021). The psychological symptom burden in partners of pancreatic cancer patients: A population-based cohort study. Supportive Care in Cancer, 29, 6689–6699.CrossRefPubMed Dengso, K. E., Thomsen, T., Andersen, E. W., Hansen, C. P., Christensen, B. M., Hillingso, J., & Dalton, S. O. (2021). The psychological symptom burden in partners of pancreatic cancer patients: A population-based cohort study. Supportive Care in Cancer, 29, 6689–6699.CrossRefPubMed
go back to reference Desai, A., & Gyawali, B. (2020). Financial toxicity of cancer treatment: Moving the discussion from acknowledgement of the problem to identifying solutions. EClinicalMedicine, 20, 100269.CrossRefPubMedPubMedCentral Desai, A., & Gyawali, B. (2020). Financial toxicity of cancer treatment: Moving the discussion from acknowledgement of the problem to identifying solutions. EClinicalMedicine, 20, 100269.CrossRefPubMedPubMedCentral
go back to reference Engebretson, A., Matrisian, L., & Thompson, C. (2015). Pancreatic cancer: Patient and caregiver perceptions on diagnosis, psychological impact, and importance of support. Pancreatology, 15, 701–707.CrossRefPubMed Engebretson, A., Matrisian, L., & Thompson, C. (2015). Pancreatic cancer: Patient and caregiver perceptions on diagnosis, psychological impact, and importance of support. Pancreatology, 15, 701–707.CrossRefPubMed
go back to reference Fong, Z. V., Alvino, D. M., Castillo, C. F., Nipp, R. D., Traeger, L. N., Ruddy, M., Lubitz, C. C., Johnson, C. D., Chang, D. C., Warshaw, A. L., Lillemoe, K. D., & Ferrone, C. R. (2017). Health-related quality of life and functional outcomes in 5-year survivors after pancreaticoduodenectomy. Annals of Surgery, 266, 685–692.CrossRefPubMed Fong, Z. V., Alvino, D. M., Castillo, C. F., Nipp, R. D., Traeger, L. N., Ruddy, M., Lubitz, C. C., Johnson, C. D., Chang, D. C., Warshaw, A. L., Lillemoe, K. D., & Ferrone, C. R. (2017). Health-related quality of life and functional outcomes in 5-year survivors after pancreaticoduodenectomy. Annals of Surgery, 266, 685–692.CrossRefPubMed
go back to reference Gaddam, S., Abboud, Y., Oh, J., Samaan, J. S., Nissen, N. N., Lu, S. C., & Lo, S. K. (2021). Incidence of pancreatic cancer by age and sex in the US, 2000–2018. JAMA, 326, 2075–2077.CrossRefPubMedPubMedCentral Gaddam, S., Abboud, Y., Oh, J., Samaan, J. S., Nissen, N. N., Lu, S. C., & Lo, S. K. (2021). Incidence of pancreatic cancer by age and sex in the US, 2000–2018. JAMA, 326, 2075–2077.CrossRefPubMedPubMedCentral
go back to reference Gratao, A. C. M., Brigola, A. G., Ottaviani, A. C., Luchesi, B. M., Souza, E. N., Rossetti, E. S., de Oliveira, N. A., Terassi, M., & Pavarini, S. C. I. (2019). Brief version of Zarit Burden Interview (ZBI) for burden assessment in older caregivers. Dement Neuropsychologia, 13, 122–129.CrossRef Gratao, A. C. M., Brigola, A. G., Ottaviani, A. C., Luchesi, B. M., Souza, E. N., Rossetti, E. S., de Oliveira, N. A., Terassi, M., & Pavarini, S. C. I. (2019). Brief version of Zarit Burden Interview (ZBI) for burden assessment in older caregivers. Dement Neuropsychologia, 13, 122–129.CrossRef
go back to reference Hagedoorn, M., Sanderman, R., Bolks, H. N., Tuinstra, J., & Coyne, J. C. (2008). Distress in couples coping with cancer: A meta-analysis and critical review of role and gender effects. Psychological Bulletin, 134, 1–30.CrossRefPubMed Hagedoorn, M., Sanderman, R., Bolks, H. N., Tuinstra, J., & Coyne, J. C. (2008). Distress in couples coping with cancer: A meta-analysis and critical review of role and gender effects. Psychological Bulletin, 134, 1–30.CrossRefPubMed
go back to reference Hagell, P., Alvariza, A., Westergren, A., & Arestedt, K. (2017). Assessment of burden among family caregivers of people with parkinson’s disease using the Zarit burden interview. Journal of Pain and Symptom Management, 53, 272–278.CrossRefPubMed Hagell, P., Alvariza, A., Westergren, A., & Arestedt, K. (2017). Assessment of burden among family caregivers of people with parkinson’s disease using the Zarit burden interview. Journal of Pain and Symptom Management, 53, 272–278.CrossRefPubMed
go back to reference Hodges, L. J., Humphris, G. M., & Macfarlane, G. (2005). A meta-analytic investigation of the relationship between the psychological distress of cancer patients and their carers. Social Science and Medicine, 60, 1–12.CrossRefPubMed Hodges, L. J., Humphris, G. M., & Macfarlane, G. (2005). A meta-analytic investigation of the relationship between the psychological distress of cancer patients and their carers. Social Science and Medicine, 60, 1–12.CrossRefPubMed
go back to reference Ikeda, A., Kawachi, I., Iso, H., Iwasaki, M., Inoue, M., & Tsugane, S. (2013). Social support and cancer incidence and mortality: The JPHC study cohort II. Cancer Causes and Control, 24, 847–860.CrossRefPubMed Ikeda, A., Kawachi, I., Iso, H., Iwasaki, M., Inoue, M., & Tsugane, S. (2013). Social support and cancer incidence and mortality: The JPHC study cohort II. Cancer Causes and Control, 24, 847–860.CrossRefPubMed
go back to reference Jacobs, J. M., Shaffer, K. M., Nipp, R. D., Fishbein, J. N., MacDonald, J., El-Jawahri, A., Pirl, W. F., Jackson, V. A., Park, E. R., Temel, J. S., & Greer, J. A. (2017). Distress is Interdependent in patients and caregivers with newly diagnosed incurable cancers. Annals of Behavioral Medicine, 51, 519–531.CrossRefPubMed Jacobs, J. M., Shaffer, K. M., Nipp, R. D., Fishbein, J. N., MacDonald, J., El-Jawahri, A., Pirl, W. F., Jackson, V. A., Park, E. R., Temel, J. S., & Greer, J. A. (2017). Distress is Interdependent in patients and caregivers with newly diagnosed incurable cancers. Annals of Behavioral Medicine, 51, 519–531.CrossRefPubMed
go back to reference Jacobsen, P. B., Donovan, K. A., Trask, P. C., Fleishman, S. B., Zabora, J., Baker, F., & Holland, J. C. (2005). Screening for psychologic distress in ambulatory cancer patients. Cancer, 103, 1494–1502.CrossRefPubMed Jacobsen, P. B., Donovan, K. A., Trask, P. C., Fleishman, S. B., Zabora, J., Baker, F., & Holland, J. C. (2005). Screening for psychologic distress in ambulatory cancer patients. Cancer, 103, 1494–1502.CrossRefPubMed
go back to reference Janda, M., Neale, R. E., Klein, K., O’Connell, D. L., Gooden, H., Goldstein, D., Merrett, N. D., Wyld, D. K., Rowlands, I. J., & Beesley, V. L. (2017). Anxiety, depression and quality of life in people with pancreatic cancer and their carers. Pancreatology, 17, 321–327.CrossRefPubMed Janda, M., Neale, R. E., Klein, K., O’Connell, D. L., Gooden, H., Goldstein, D., Merrett, N. D., Wyld, D. K., Rowlands, I. J., & Beesley, V. L. (2017). Anxiety, depression and quality of life in people with pancreatic cancer and their carers. Pancreatology, 17, 321–327.CrossRefPubMed
go back to reference Jensen, R. E., Potosky, A. L., Moinpour, C. M., Lobo, T., Cella, D., Hahn, E. A., Thissen, D., Smith, A. W., Ahn, J., Luta, G., & Reeve, B. B. (2017). United States population-based estimates of patient-reported outcomes measurement information system symptom and functional status reference values for individuals with cancer. Journal of Clinical Oncology, 35, 1913–1920.CrossRefPubMedPubMedCentral Jensen, R. E., Potosky, A. L., Moinpour, C. M., Lobo, T., Cella, D., Hahn, E. A., Thissen, D., Smith, A. W., Ahn, J., Luta, G., & Reeve, B. B. (2017). United States population-based estimates of patient-reported outcomes measurement information system symptom and functional status reference values for individuals with cancer. Journal of Clinical Oncology, 35, 1913–1920.CrossRefPubMedPubMedCentral
go back to reference Katz, M. H., Shi, Q., Ahmad, S. A., Herman, J. M., Marsh Rde, W., Collisson, E., Schwartz, L., Frankel, W., Martin, R., Conway, W., Truty, M., Kindler, H., Lowy, A. M., Bekaii-Saab, T., Philip, P., Talamonti, M., Cardin, D., LoConte, N., Shen, P., … Venook, A. P. (2016). Preoperative modified folfirinox treatment followed by capecitabine-based chemoradiation for borderline resectable pancreatic cancer: alliance for clinical trials in oncology trial A021101. JAMA Surgery, 151, e161137.CrossRefPubMedPubMedCentral Katz, M. H., Shi, Q., Ahmad, S. A., Herman, J. M., Marsh Rde, W., Collisson, E., Schwartz, L., Frankel, W., Martin, R., Conway, W., Truty, M., Kindler, H., Lowy, A. M., Bekaii-Saab, T., Philip, P., Talamonti, M., Cardin, D., LoConte, N., Shen, P., … Venook, A. P. (2016). Preoperative modified folfirinox treatment followed by capecitabine-based chemoradiation for borderline resectable pancreatic cancer: alliance for clinical trials in oncology trial A021101. JAMA Surgery, 151, e161137.CrossRefPubMedPubMedCentral
go back to reference Kroenke, K., Yu, Z., Wu, J., Kean, J., & Monahan, P. O. (2014). Operating characteristics of PROMIS four-item depression and anxiety scales in primary care patients with chronic pain. Pain Medicine, 15, 1892–1901.CrossRefPubMedPubMedCentral Kroenke, K., Yu, Z., Wu, J., Kean, J., & Monahan, P. O. (2014). Operating characteristics of PROMIS four-item depression and anxiety scales in primary care patients with chronic pain. Pain Medicine, 15, 1892–1901.CrossRefPubMedPubMedCentral
go back to reference Lee, E. H. (2012). Review of the psychometric evidence of the perceived stress scale. Asian Nurs Res (korean Soc Nurs Sci), 6, 121–127. Lee, E. H. (2012). Review of the psychometric evidence of the perceived stress scale. Asian Nurs Res (korean Soc Nurs Sci), 6, 121–127.
go back to reference Martinez, P., Galdon, M. J., Andreu, Y., & Ibanez, E. (2013). The Distress Thermometer in Spanish cancer patients: Convergent validity and diagnostic accuracy. Supportive Care in Cancer, 21, 3095–3102.CrossRefPubMed Martinez, P., Galdon, M. J., Andreu, Y., & Ibanez, E. (2013). The Distress Thermometer in Spanish cancer patients: Convergent validity and diagnostic accuracy. Supportive Care in Cancer, 21, 3095–3102.CrossRefPubMed
go back to reference Matthews, B., Baker, F., & Spillers, R. (2003). Family caregivers and indicators of cancer-related distress. Psychology, Health & Medicine, 8, 46–56.CrossRef Matthews, B., Baker, F., & Spillers, R. (2003). Family caregivers and indicators of cancer-related distress. Psychology, Health & Medicine, 8, 46–56.CrossRef
go back to reference Mitchell, A. J. (2010). Short screening tools for cancer-related distress: A review and diagnostic validity meta-analysis. Journal of the National Comprehensive Cancer Network, 8, 487–494.CrossRefPubMed Mitchell, A. J. (2010). Short screening tools for cancer-related distress: A review and diagnostic validity meta-analysis. Journal of the National Comprehensive Cancer Network, 8, 487–494.CrossRefPubMed
go back to reference Neoptolemos, J. P., Palmer, D. H., Ghaneh, P., Psarelli, E. E., Valle, J. W., Halloran, C. M., Faluyi, O., O’Reilly, D. A., Cunningham, D., Wadsley, J., Darby, S., Meyer, T., Gillmore, R., Anthoney, A., Lind, P., Glimelius, B., Falk, S., Izbicki, J. R., Middleton, G. W., … Büchler, M. W. (2017). Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial. The Lancet, 389, 1011–1024. https://doi.org/10.1016/S0140-6736(16)32409-6CrossRef Neoptolemos, J. P., Palmer, D. H., Ghaneh, P., Psarelli, E. E., Valle, J. W., Halloran, C. M., Faluyi, O., O’Reilly, D. A., Cunningham, D., Wadsley, J., Darby, S., Meyer, T., Gillmore, R., Anthoney, A., Lind, P., Glimelius, B., Falk, S., Izbicki, J. R., Middleton, G. W., … Büchler, M. W. (2017). Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial. The Lancet, 389, 1011–1024. https://​doi.​org/​10.​1016/​S0140-6736(16)32409-6CrossRef
go back to reference Northouse, L. L., Katapodi, M. C., Schafenacker, A. M., & Weiss, D. (2012). The impact of caregiving on the psychological well-being of family caregivers and cancer patients. Seminars in Oncology Nursing, 28, 236–245.CrossRefPubMed Northouse, L. L., Katapodi, M. C., Schafenacker, A. M., & Weiss, D. (2012). The impact of caregiving on the psychological well-being of family caregivers and cancer patients. Seminars in Oncology Nursing, 28, 236–245.CrossRefPubMed
go back to reference Northouse, L., Templin, T., & Mood, D. (2001). Couples’ adjustment to breast disease during the first year following diagnosis. Journal of Behavioral Medicine, 24, 115–136.CrossRefPubMed Northouse, L., Templin, T., & Mood, D. (2001). Couples’ adjustment to breast disease during the first year following diagnosis. Journal of Behavioral Medicine, 24, 115–136.CrossRefPubMed
go back to reference Schenker, Y., Bahary, N., Claxton, R., Childers, J., Chu, E., Kavalieratos, D., King, L., Lembersky, B., Tiver, G., & Arnold, R. M. (2018). A pilot trial of early specialty palliative care for patients with advanced pancreatic cancer: challenges encountered and lessons learned. Journal of Palliative Medicine, 21, 28–36.CrossRefPubMedPubMedCentral Schenker, Y., Bahary, N., Claxton, R., Childers, J., Chu, E., Kavalieratos, D., King, L., Lembersky, B., Tiver, G., & Arnold, R. M. (2018). A pilot trial of early specialty palliative care for patients with advanced pancreatic cancer: challenges encountered and lessons learned. Journal of Palliative Medicine, 21, 28–36.CrossRefPubMedPubMedCentral
go back to reference Siegel, R. L., Miller, K. D., Fuchs, H. E., & Jemal, A. (2022). Cancer statistics. CA: A Cancer Journal for Clinicians, 72, 7–33. Siegel, R. L., Miller, K. D., Fuchs, H. E., & Jemal, A. (2022). Cancer statistics. CA: A Cancer Journal for Clinicians, 72, 7–33.
go back to reference van Ryn, M., Sanders, S., Kahn, K., van Houtven, C., Griffin, J. M., Martin, M., Atienza, A. A., Phelan, S., Finstad, D., & Rowland, J. (2011). Objective burden, resources, and other stressors among informal cancer caregivers: A hidden quality issue? Psycho-Oncology, 20, 44–52.CrossRefPubMedPubMedCentral van Ryn, M., Sanders, S., Kahn, K., van Houtven, C., Griffin, J. M., Martin, M., Atienza, A. A., Phelan, S., Finstad, D., & Rowland, J. (2011). Objective burden, resources, and other stressors among informal cancer caregivers: A hidden quality issue? Psycho-Oncology, 20, 44–52.CrossRefPubMedPubMedCentral
go back to reference Von Hoff, D. D., Ervin, T., Arena, F. P., Chiorean, E. G., Infante, J., Moore, M., Seay, T., Tjulandin, S. A., Ma, W. W., Saleh, M. N., Harris, M., Reni, M., Dowden, S., Laheru, D., Bahary, N., Ramanathan, R. K., Tabernero, J., Hidalgo, M., Goldstein, D., … Renschler, M. F. (2013). Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine. New England Journal of Medicine, 369, 1691–1703.CrossRef Von Hoff, D. D., Ervin, T., Arena, F. P., Chiorean, E. G., Infante, J., Moore, M., Seay, T., Tjulandin, S. A., Ma, W. W., Saleh, M. N., Harris, M., Reni, M., Dowden, S., Laheru, D., Bahary, N., Ramanathan, R. K., Tabernero, J., Hidalgo, M., Goldstein, D., … Renschler, M. F. (2013). Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine. New England Journal of Medicine, 369, 1691–1703.CrossRef
go back to reference Warttig, S. L., Forshaw, M. J., South, J., & White, A. K. (2013). New, normative, english-sample data for the short form perceived stress scale (PSS-4). Journal of Health Psychology, 18, 1617–1628.CrossRefPubMed Warttig, S. L., Forshaw, M. J., South, J., & White, A. K. (2013). New, normative, english-sample data for the short form perceived stress scale (PSS-4). Journal of Health Psychology, 18, 1617–1628.CrossRefPubMed
go back to reference Xia, B. T., & Ahmad, S. A. (2016). Clinical considerations for pancreatic cancer. Seminars in Roentgenology, 51, 74–81.CrossRefPubMed Xia, B. T., & Ahmad, S. A. (2016). Clinical considerations for pancreatic cancer. Seminars in Roentgenology, 51, 74–81.CrossRefPubMed
Metagegevens
Titel
Patient-caregiver dyads in pancreatic cancer: identification of patient and caregiver factors associated with caregiver well-being
Auteurs
Brent T. Xia
Amy K. Otto
Kelvin Allenson
Maria Kocab
Wenyi Fan
Qianxing Mo
Jason W. Denbo
Mokenge P. Malafa
Jennifer B. Permuth
Dae Won Kim
Jason B. Fleming
Maija Reblin
Pamela J. Hodul
Publicatiedatum
20-08-2022
Uitgeverij
Springer US
Gepubliceerd in
Journal of Behavioral Medicine / Uitgave 6/2022
Print ISSN: 0160-7715
Elektronisch ISSN: 1573-3521
DOI
https://doi.org/10.1007/s10865-022-00354-x

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