Research on indulgent parenting and its relation to college students is both limited and inconsistent. Further, all the studies have used a variable-centered approach. To fill the gap in the current literature, the aims of this study were to explore profiles of parental indulgence and their associations with college students’ emotional and behavioral problems. The sample in this study consisted of college students from two universities. Participants were asked to take an online survey about their perceptions of their parents’ indulgent parenting practice and their own well-being. Results from latent profile analyses suggested distinct profiles of parental indulgence for mothers and fathers. Further, these profiles demonstrated differential associations with college students’ anxiety and depressive symptoms, emotional dysregulation, and alcohol use. Implications were also noted.