This study aimed to identify factors that affect the health behaviors of married immigrant women and Korean husbands towards their young children. Our cross-sectional descriptive study included 169 married immigrant women and 143 Korean husbands. Data were collected through self-report questionnaires and analyzed using multiple regression, with SPSS/Win 23.0 software. The significant differences between married immigrant women and Korean husbands included parental health behavior towards young children (t = 4.66, p < 0.001), parenting efficacy (t = 3.73, p < 0.001), intercultural adaptation attitudes (t = 4.94, p < 0.001) and family strength (t = 2.52, p = 0.012). Parental health behavior was significantly positively correlated with parenting efficacy, intercultural adaptation attitudes, and family strength, in both married immigrant women and Korean husbands. A multiple regression analysis showed that the factors affecting parental health behavior in married immigrant women were family strength (β = 0.31, p < 0.001) and intercultural adaptation attitudes (β = 0.25, p = 0.002), whereas factors affecting Korean husbands were family strength (β = 0.36, p < 0.001) and parenting efficacy (β = 0.19, p = 0.046). Specifically, the factors that most influenced parental health behavior was family strength, for both married immigrant women and Korean husbands. Considering the results of this study, a family-focused approach is necessary to promote parental health behaviors toward young children in multicultural families. Furthermore, intervention strategies should be implemented to support the intercultural adaptation attitudes of parents in multicultural families and improve the parenting of Korean husbands.