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Journal of Autism and Developmental Disorders
Gepubliceerd in: Journal of Autism and Developmental Disorders 11/2013

01-11-2013 | Original Paper

Parental Age and Risk of Autism Spectrum Disorders in a Finnish National Birth Cohort

Auteurs: Katja M. Lampi, Susanna Hinkka-Yli-Salomäki, Venla Lehti, Hans Helenius, Mika Gissler, Alan S. Brown, Andre Sourander

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 11/2013

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Abstract

Aim of the study was to examine the associations between parental age and autism spectrum disorders (ASD). Data were based on the FIPS-A (Finnish Prenatal Study of Autism and Autism Spectrum Disorders), a case-control study with a total of 4,713 cases with childhood autism (n = 1,132), Asperger’s syndrome (n = 1,785) or other pervasive developmental disorder (PDD) (n = 1,796), which were ascertained from the Finnish Hospital Discharge Register. Controls were selected from the Finnish Medical Birth Register. Conditional logistic regression models were used for statistical analyses. Advanced paternal age (35–49 years) was associated with childhood autism in offspring, whereas advanced maternal age was associated with both Asperger’s syndrome and PDD in offspring (35 years or more and 40 years or more, respectively). Teenage motherhood (19 years or less) was associated with PDD in offspring. The main finding was that maternal and paternal ages were differentially associated with ASD subtypes. In addition to advanced parental age, teenage pregnancy seems to incur a risk for PDD in offspring.
vorige artikel Comparison of ICD-10R, DSM-IV-TR and DSM-5 in an Adult Autism Spectrum Disorder Diagnostic Clinic
volgende artikel The Influences of Face Inversion and Facial Expression on Sensitivity to Eye Contact in High-Functioning Adults with Autism Spectrum Disorders
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Metagegevens
Titel
Parental Age and Risk of Autism Spectrum Disorders in a Finnish National Birth Cohort
Auteurs
Katja M. Lampi
Susanna Hinkka-Yli-Salomäki
Venla Lehti
Hans Helenius
Mika Gissler
Alan S. Brown
Andre Sourander
Publicatiedatum
01-11-2013
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 11/2013
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-013-1801-3

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