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Gepubliceerd in: Journal of Autism and Developmental Disorders 8/2020

10-02-2020 | Original Paper

Pain Modulation Mechanisms in ASD Adults

Auteurs: A. Dubois, M. Boudjarane, A. Le Fur-Bonnabesse, A. Dion, G. L’heveder, B. Quinio, M. Walter, S. Marchand, C. Bodéré

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 8/2020

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Abstract

We tested endogenous pain modulation mechanisms in adults with autism spectrum disorders (ASD). Nineteen ASD adults without intellectual disabilities were included, matched with 19 healthy volunteers on the basis of sex and chronological age. An experimental pain model was used to measure excitatory and inhibitory pain mechanisms in a single session. Statistical analyses indicated that endogenous pain modulation mechanisms in ASD group did not differ significantly from those of healthy adults. The pain scores were very disparate in ASD group with a greater range of extreme scores than in control group. Unlike schizophrenic patients, there was no systematic dysfunction of endogenous excitatory pain modulation mechanisms, but the high variability requires to be wise to interpret the results and formulate conclusion
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Metagegevens
Titel
Pain Modulation Mechanisms in ASD Adults
Auteurs
A. Dubois
M. Boudjarane
A. Le Fur-Bonnabesse
A. Dion
G. L’heveder
B. Quinio
M. Walter
S. Marchand
C. Bodéré
Publicatiedatum
10-02-2020
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 8/2020
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-019-04361-x

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