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Gepubliceerd in: Quality of Life Research 6/2013

01-08-2013

Pain and other symptoms and their relationship to quality of life in cancer patients on opioids

Auteurs: Sigridur Zoëga, Nanna Fridriksdottir, Valgerdur Sigurdardottir, Sigridur Gunnarsdottir

Gepubliceerd in: Quality of Life Research | Uitgave 6/2013

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Abstract

Purpose

The purpose of this study was to assess pain, other symptoms and QOL, and the relationship between these variables, among cancer patients on strong opioids.

Methods

The study was cross-sectional, descriptive, and correlational. A convenience sample of 150 cancer patients, ≥18 years, all on strong opioids for ≥3 days was recruited.

Results

The mean (SD) age was 64.7 (12.7) years, and 59 % were women. Mean (SD) time from cancer diagnosis was 36.3 (55.1) months. The median number of symptoms was 9, range 1–16 and the mean (SD) severity was 1.9 (0.5) on a 1–4 scale. Pain was one of the most prevalent (90 %) and severe symptoms with a mean (SD) of 2.56 (0.9). Number of symptoms explained 25.8 % of the variance in QOL, adjusted for age and sex. Another model, also adjusted for age and sex, showed that pain, fatigue, insomnia and depression, explained 33.6 % of the variance in QOL.

Conclusions

The symptomatology in this study was similar to studies on patients with advanced cancer. QOL was associated with the number of symptoms patients experience and individual symptoms, notably fatigue and pain. Despite the use of strong opioids, pain was both common and severe, suggesting under-treatment. Pain and other symptoms need to be assessed and managed in order to improve patients’ QOL. Special attention needs to be paid to multisymptom management in patients on opioids.
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Metagegevens
Titel
Pain and other symptoms and their relationship to quality of life in cancer patients on opioids
Auteurs
Sigridur Zoëga
Nanna Fridriksdottir
Valgerdur Sigurdardottir
Sigridur Gunnarsdottir
Publicatiedatum
01-08-2013
Uitgeverij
Springer Netherlands
Gepubliceerd in
Quality of Life Research / Uitgave 6/2013
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-012-0264-x