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2014 | OriginalPaper | Hoofdstuk

24. Oesofaguscarcinoom

Auteurs : Christine Kestens, Richard van Hillegersberg, Peter Siersema

Gepubliceerd in: Ontwikkelingen in de oncologie

Uitgeverij: Bohn Stafleu van Loghum

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Inleiding

Het oesofaguscarcinoom (figuur 24.1) is de op achtst na meest voorkomende en de op zes na dodelijkste kanker in de wereld. Histopathologisch onderscheidt men twee groepen oesofaguscarcinomen: adenocarcinomen en plaveiselcelcarcinomen. Algemeen wordt verondersteld dat adenocarcinomen zich ontwikkelen in een barrettoesofagus. Een barrettoesofagus ontstaat door metaplasie van plaveiselepitheel, dat onder invloed van gastro-oesofageale reflux transformeert tot intestinaal cilinderepitheel (figuur 24.2).
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Metagegevens
Titel
Oesofaguscarcinoom
Auteurs
Christine Kestens
Richard van Hillegersberg
Peter Siersema
Copyright
2014
Uitgeverij
Bohn Stafleu van Loghum
DOI
https://doi.org/10.1007/978-90-368-0436-3_24