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Gepubliceerd in: Bijblijven 2/2006

01-02-2006 | Artikelen

Neuropathische pijn: een complexe pathologie

Auteur: Prof. dr. Kris C.P. Vissers

Gepubliceerd in: Bijblijven | Uitgave 2/2006

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Samenvatting

Neuropathische pijn kan bij patiënten met kanker een moeilijk behandelbaar probleem vormen. Zij wordt gedefinieerd als pijn ten gevolge van een zenuwletsel. Er zijn verschillende mogelijke oorzaken van neuropathische pijn. Zelfs met behulp van geavanceerde onderzoekstechnieken is de diagnosestelling van neuropathische pijn niet eenvoudig, daarom moet een logisch uitgebouwd diagnostisch schema gevolgd worden. Neuropathische pijn gaat veelal gepaard met overgevoeligheid voor pijnlijke prikkels (hyperalgesie) en gevoeligheid voor niet-pijnlijke prikkels (allodynie). Het gebruik van opioïden bij de behandeling van neuropathische pijn werd ter discussie gesteld, alhoewel deze producten aanvullend kunnen zijn op de zogenaamde co-analgetica, waarvan de tricyclische antidepressiva en de anti-epileptica, carbamazepine en gabapentine het uitvoerigst gedocumenteerd zijn. Verder onderzoek naar de ontstaansmechanismen van neuropathische pijn moet bijdragen tot het ontwikkelen van meer mechanismegeoriënteerde behandelingen.
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Metagegevens
Titel
Neuropathische pijn: een complexe pathologie
Auteur
Prof. dr. Kris C.P. Vissers
Publicatiedatum
01-02-2006
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Bijblijven / Uitgave 2/2006
Print ISSN: 0168-9428
Elektronisch ISSN: 1876-4916
DOI
https://doi.org/10.1007/BF03059912

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