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Gepubliceerd in:

02-06-2016

Neural Reactivity to Angry Faces Predicts Treatment Response in Pediatric Anxiety

Auteurs: Nora Bunford, Autumn Kujawa, Kate D. Fitzgerald, James E. Swain, Gregory L. Hanna, Elizabeth Koschmann, David Simpson, Sucheta Connolly, Christopher S. Monk, K. Luan Phan

Gepubliceerd in: Research on Child and Adolescent Psychopathology | Uitgave 2/2017

Abstract

Although cognitive-behavioral psychotherapy (CBT) and pharmacotherapy are evidence-based treatments for pediatric anxiety, many youth with anxiety disorders fail to respond to these treatments. Given limitations of clinical measures in predicting treatment response, identifying neural predictors is timely. In this study, 35 anxious youth (ages 7–19 years) completed an emotional face-matching task during which the late positive potential (LPP), an event-related potential (ERP) component that indexes sustained attention towards emotional stimuli, was measured. Following the ERP measurement, youth received CBT or selective serotonin reuptake inhibitor (SSRI) treatment, and the LPP was examined as a predictor of treatment response. Findings indicated that, accounting for pre-treatment anxiety severity, neural reactivity to emotional faces predicted anxiety severity post- CBT and SSRI treatment such that enhanced electrocortical response to angry faces was associated with better treatment response. An enhanced LPP to angry faces may predict treatment response insofar as it may reflect greater emotion dysregulation or less avoidance and/or enhanced engagement with environmental stimuli in general, including with treatment.

vorige artikel Linking Social Anxiety with Social Competence in Early Adolescence: Physiological and Coping Moderators

volgende artikel Anxiety and Depression Symptom Dimensions Demonstrate Unique Relationships with the Startle Reflex in Anticipation of Unpredictable Threat in 8 to 14 Year-Old Girls

The results of independent samples t-tests also indicated no difference between males and females with regard to LPP or post-treatment anxiety severity (all ps > 0.18).

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Titel: Neural Reactivity to Angry Faces Predicts Treatment Response in Pediatric Anxiety
Auteurs: Nora Bunford
Autumn Kujawa
Kate D. Fitzgerald
James E. Swain
Gregory L. Hanna
Elizabeth Koschmann
David Simpson
Sucheta Connolly
Christopher S. Monk
K. Luan Phan
Publicatiedatum: 02-06-2016
Uitgeverij: Springer US
Gepubliceerd in: Research on Child and Adolescent Psychopathology / Uitgave 2/2017
Print ISSN: 2730-7166
Elektronisch ISSN: 2730-7174
DOI: https://doi.org/10.1007/s10802-016-0168-2

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