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01-01-2013 | Original paper

Neural Mechanisms of Improvements in Social Motivation After Pivotal Response Treatment: Two Case Studies

Auteurs: Avery C. Voos, Kevin A. Pelphrey, Jonathan Tirrell, Danielle Z. Bolling, Brent Vander Wyk, Martha D. Kaiser, James C. McPartland, Fred R. Volkmar, Pamela Ventola

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 1/2013

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Abstract

Pivotal response treatment (PRT) is an empirically validated behavioral treatment that has widespread positive effects on communication, behavior, and social skills in young children with autism spectrum disorder (ASD). For the first time, functional magnetic resonance imaging was used to identify the neural correlates of successful response to PRT in two young children with ASD. Baseline measures of social communication, adaptive behavior, eye tracking and neural response to social stimuli were taken prior to treatment and after 4 months of PRT. Both children showed striking gains on behavioral measures and also showed increased activation to social stimuli in brain regions utilized by typically developing children. These results suggest that neural systems supporting social perception are malleable through implementation of PRT.
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Metagegevens
Titel
Neural Mechanisms of Improvements in Social Motivation After Pivotal Response Treatment: Two Case Studies
Auteurs
Avery C. Voos
Kevin A. Pelphrey
Jonathan Tirrell
Danielle Z. Bolling
Brent Vander Wyk
Martha D. Kaiser
James C. McPartland
Fred R. Volkmar
Pamela Ventola
Publicatiedatum
01-01-2013
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 1/2013
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-012-1683-9