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18-02-2019 | Original Paper

Network Analysis of Behaviors in the Depression and Autism Realms: Inter-Relationships and Clinical Implications

Tijdschrift:
Journal of Autism and Developmental Disorders
Auteurs:
Farhad Montazeri, Annelies de Bildt, Vera Dekker, George M. Anderson
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Electronic supplementary material

The online version of this article (https://​doi.​org/​10.​1007/​s10803-019-03914-4) contains supplementary material, which is available to authorized users.

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Abstract

Depression-, anxiety-, OCD- and autism-related behaviors were assessed in 118 high-functioning individuals with autism spectrum disorders (ASD) and in 2016 controls. The ASD group had a higher rate of clinical depression and markedly higher “insomnia” and “restlessness” scores. Network analysis and hierarchical cluster analysis in the ASD group revealed that depression and anxiety items clustered together, but separately from autism-related items. Compared to controls, “insomnia” and “restlessness” items in the ASD network of depression items were much more central (higher closeness, and betweenness centrality). Combined networks of depression-, anxiety-, and OCD-related items revealed that the control group depression item module was not preserved in ASD. The results indicate that depression is atypical in autism and suggest specific intervention targets.

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Extra materiaal
Supplementary material 1 (DOCX 653 KB)
10803_2019_3914_MOESM1_ESM.docx
Supplementary material 2 (DOCX 23 KB)
10803_2019_3914_MOESM2_ESM.docx
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