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Gepubliceerd in: Journal of Autism and Developmental Disorders 5/2006

01-07-2006 | Original Paper

Motor Signs Distinguish Children with High Functioning Autism and Asperger’s Syndrome from Controls

Auteurs: Eva M. Jansiewicz, Melissa C. Goldberg, Craig J. Newschaffer, Martha B. Denckla, Rebecca Landa, Stewart H. Mostofsky

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 5/2006

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Abstract

While many studies of motor control in autism have focused on specific motor signs, there has been a lack of research examining the complete range of subtle neuromotor signs. This study compared performance on a neurologic examination standardized for children (PANESS, Physical and Neurological Exam for Subtle Signs, Denckla [1974 Developmental Medicine and Child Neurology, 16(6), 729–741]) between a group of 40 boys aged 6–17 with autism and average range IQs and a group of 55 typically developing boys. The Autism group was shown to have significant impairment on several measures of motor control compared to the Control group. Regression analyses revealed that a model including four PANESS variables offered a high level of discrimination in distinguishing boys with high-functioning autism from controls.
Literatuur
go back to reference American Psychiatric Association (APA) (1994). Diagnostic and statistical manual of mental disorders, 4th edn. Washington, DC. American Psychiatric Association (APA) (1994). Diagnostic and statistical manual of mental disorders, 4th edn. Washington, DC.
go back to reference Bruininks, R. H. (1978). The Bruininks–Oseretsky test of motor proficiency. Circle Pines, MN: American Guidance Service. Bruininks, R. H. (1978). The Bruininks–Oseretsky test of motor proficiency. Circle Pines, MN: American Guidance Service.
go back to reference Cox, A. D. (1991). Is Asperger’s syndrome a useful diagnosis? Archives of Disease in Childhood, 66, 259–262. PubMed Cox, A. D. (1991). Is Asperger’s syndrome a useful diagnosis? Archives of Disease in Childhood, 66, 259–262. PubMed
go back to reference Denckla, M. B. (1974). Development of motor co-ordination in normal children. Developmental Medicine and Child Neurology, 16(6), 729–741. PubMedCrossRef Denckla, M. B. (1974). Development of motor co-ordination in normal children. Developmental Medicine and Child Neurology, 16(6), 729–741. PubMedCrossRef
go back to reference Denckla, M. B., & Rudel, R. G. (1978). Anomalies of motor development in hyperactive boys. Annals of Neurology, 3(3), 231–233. CrossRefPubMed Denckla, M. B., & Rudel, R. G. (1978). Anomalies of motor development in hyperactive boys. Annals of Neurology, 3(3), 231–233. CrossRefPubMed
go back to reference Denckla, M. B., Rudel, R.G., Chapman, C., & Krieger, J. (1985). Motor proficiency in dyslexic children with and without attentional disorders. Archives of Neurology, 42, 228–231. PubMed Denckla, M. B., Rudel, R.G., Chapman, C., & Krieger, J. (1985). Motor proficiency in dyslexic children with and without attentional disorders. Archives of Neurology, 42, 228–231. PubMed
go back to reference Firth, U. (1991). Autism and Asperger syndrome. Cambridge, UK: Cambridge University Press. Firth, U. (1991). Autism and Asperger syndrome. Cambridge, UK: Cambridge University Press.
go back to reference Ghaziuddin, M., & Butler, E. (1998). Clumsiness in autism and Asperger syndrome: A further report. Journal of Intellectual Disability Research, 42, 43–48. CrossRefPubMed Ghaziuddin, M., & Butler, E. (1998). Clumsiness in autism and Asperger syndrome: A further report. Journal of Intellectual Disability Research, 42, 43–48. CrossRefPubMed
go back to reference Ghaziuddin, M., Butler, E., Tsai, L.Y., & Ghaziuddin, N. (1994). Is clumsiness a marker for Asperger syndrome? Journal of Intellectual Disability Research, 38, 519–527. PubMedCrossRef Ghaziuddin, M., Butler, E., Tsai, L.Y., & Ghaziuddin, N. (1994). Is clumsiness a marker for Asperger syndrome? Journal of Intellectual Disability Research, 38, 519–527. PubMedCrossRef
go back to reference Ghaziuddin, M., Tsai, L. Y., & Ghaziuddin, N. (1992). A reappraisal of clumsiness as a diagnostic feature of Asperger syndrome. Journal of Autism and Developmental Disorders, 22, 651–656. CrossRefPubMed Ghaziuddin, M., Tsai, L. Y., & Ghaziuddin, N. (1992). A reappraisal of clumsiness as a diagnostic feature of Asperger syndrome. Journal of Autism and Developmental Disorders, 22, 651–656. CrossRefPubMed
go back to reference Gillberg, C. (1992). The Emanuel Miller Memorial Lecture 1991: Autism and autistic-like conditions: Subclasses among disorders of empathy. Journal of Psychology and Psychiatry, 33, 813–842. CrossRef Gillberg, C. (1992). The Emanuel Miller Memorial Lecture 1991: Autism and autistic-like conditions: Subclasses among disorders of empathy. Journal of Psychology and Psychiatry, 33, 813–842. CrossRef
go back to reference Green, D., Baird, G., Barnett, A. L., Henderson, L., Huber, J., & Henderson, S. E. (2002). The severity and nature of motor impairment in Asperger’s syndrome: A comparison with specific developmental disorder of motor function. Journal of Child Psychology and Psychiatry, 43(5), 655–668. CrossRefPubMed Green, D., Baird, G., Barnett, A. L., Henderson, L., Huber, J., & Henderson, S. E. (2002). The severity and nature of motor impairment in Asperger’s syndrome: A comparison with specific developmental disorder of motor function. Journal of Child Psychology and Psychiatry, 43(5), 655–668. CrossRefPubMed
go back to reference Hallett, M., Lebiedowska, M. K., Thomas, S. L., Stanhope, S. J., Denckla, M. B., & Runsey, J. (1993). Locomotion of autistic adults. Archives of Neurology, 50(12), 1304–1308. PubMed Hallett, M., Lebiedowska, M. K., Thomas, S. L., Stanhope, S. J., Denckla, M. B., & Runsey, J. (1993). Locomotion of autistic adults. Archives of Neurology, 50(12), 1304–1308. PubMed
go back to reference Henderson, S. E., & Sugden, D. A. (1992). Movement assessment battery for children. London: Psychological Corporation. Henderson, S. E., & Sugden, D. A. (1992). Movement assessment battery for children. London: Psychological Corporation.
go back to reference Hocking, R. R. (1976). The analysis and selection of variables in linear regression. Biometrics, 32, 1–49. CrossRef Hocking, R. R. (1976). The analysis and selection of variables in linear regression. Biometrics, 32, 1–49. CrossRef
go back to reference Holden, E. W., Tarnowski, K. J., & Prinz, R. J. (1982). Reliability of neurological soft signs in children: Reevaluation of the PANESS. Journal of Abnormal Child Psychology, 10(2), 163–172. CrossRefPubMed Holden, E. W., Tarnowski, K. J., & Prinz, R. J. (1982). Reliability of neurological soft signs in children: Reevaluation of the PANESS. Journal of Abnormal Child Psychology, 10(2), 163–172. CrossRefPubMed
go back to reference Hosmer, D. W., Jovanovic B., Lemeshow S. (1989). Best subsets logistic regression. Biometrics, 45, 1265–1270. CrossRef Hosmer, D. W., Jovanovic B., Lemeshow S. (1989). Best subsets logistic regression. Biometrics, 45, 1265–1270. CrossRef
go back to reference Hughes, C. (1996). Brief report: Planning problems in autism at the level of motor control. Journal of Autism and Developmental Disorders, 26, 99–108. CrossRefPubMed Hughes, C. (1996). Brief report: Planning problems in autism at the level of motor control. Journal of Autism and Developmental Disorders, 26, 99–108. CrossRefPubMed
go back to reference Jones, V., & Prior, M. (1985). Motor imitation abilities and neurological signs in autistic children. Journal of Autism and Developmental Disorders, 15(1), 37–46. CrossRefPubMed Jones, V., & Prior, M. (1985). Motor imitation abilities and neurological signs in autistic children. Journal of Autism and Developmental Disorders, 15(1), 37–46. CrossRefPubMed
go back to reference Kadesjo, B., & Gillberg, C. (1998). Attention deficits and clumsiness in Swedish 7-year-old children. Developmental Medicine and Child Neurology, 40, 796–804. PubMedCrossRef Kadesjo, B., & Gillberg, C. (1998). Attention deficits and clumsiness in Swedish 7-year-old children. Developmental Medicine and Child Neurology, 40, 796–804. PubMedCrossRef
go back to reference Knights, R. M., & Norwood, J. A. (1979). Revised smoothed normative data on the neuropsychological test battery for children. Ottawa, Ontario, Canada: Dept. of Psychology, Carleton University. Knights, R. M., & Norwood, J. A. (1979). Revised smoothed normative data on the neuropsychological test battery for children. Ottawa, Ontario, Canada: Dept. of Psychology, Carleton University.
go back to reference Kroes, M., Kessels, A.G., Kalff, A. C., Feron, F. J., Vissers, Y. L., Jolles, J., & Vles, J. S. (2002). Quality of movement as predictor of ADHD: Results from a prospective population study in 5- and 6-year-old children. Developmental Medicine and Child Neurology, 44(11), 753–760. CrossRefPubMed Kroes, M., Kessels, A.G., Kalff, A. C., Feron, F. J., Vissers, Y. L., Jolles, J., & Vles, J. S. (2002). Quality of movement as predictor of ADHD: Results from a prospective population study in 5- and 6-year-old children. Developmental Medicine and Child Neurology, 44(11), 753–760. CrossRefPubMed
go back to reference Lord, C., Rutter, M., Goode, S., Heemsbergen J., Jordan H., Mawhood L., & Schopler, E. (1989). Autism diagnostic observation schedule: A standardized observation of communication and social behavior. Journal of Autism and Developmental Disorders, 19, 185–212. CrossRefPubMed Lord, C., Rutter, M., Goode, S., Heemsbergen J., Jordan H., Mawhood L., & Schopler, E. (1989). Autism diagnostic observation schedule: A standardized observation of communication and social behavior. Journal of Autism and Developmental Disorders, 19, 185–212. CrossRefPubMed
go back to reference Lord, C., Risi, S., Lambrecht, L., Cook, E. H. Jr., Levanthal, B. L., DiLavore, P. C., Pickles, A., & Rutter, M. (2000). The autism diagnostic observation schedule – generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30, 205–223. CrossRefPubMed Lord, C., Risi, S., Lambrecht, L., Cook, E. H. Jr., Levanthal, B. L., DiLavore, P. C., Pickles, A., & Rutter, M. (2000). The autism diagnostic observation schedule – generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30, 205–223. CrossRefPubMed
go back to reference Lord, C., Rutter, M., & LeCouteur, A. (1994). Autism diagnostic interview revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24, 659–685. CrossRefPubMed Lord, C., Rutter, M., & LeCouteur, A. (1994). Autism diagnostic interview revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24, 659–685. CrossRefPubMed
go back to reference Manjiviona, J., & Prior, M. (1995). Comparison of Asperger syndrome and high-functioning autistic children on a test of motor impairment. Journal of Autism and Developmental Disorders, 25, 23–29. CrossRefPubMed Manjiviona, J., & Prior, M. (1995). Comparison of Asperger syndrome and high-functioning autistic children on a test of motor impairment. Journal of Autism and Developmental Disorders, 25, 23–29. CrossRefPubMed
go back to reference Mawson, D., Grounds, A., & Tantam, D. (1985). Violence and Asperger’s syndrome: A case study. British Journal of Psychiatry, 147, 566–569. PubMedCrossRef Mawson, D., Grounds, A., & Tantam, D. (1985). Violence and Asperger’s syndrome: A case study. British Journal of Psychiatry, 147, 566–569. PubMedCrossRef
go back to reference Miyahara, M., Tsujii, M., Hori, M., Nakanishi, K., Kageyama, H., & Sugiyama, T. (1997). Brief report: Motor incoordination in children with Asperger’s syndrome and learning disabilities. Journal of Autism and Developmental Disorders, 27, 595–603. CrossRefPubMed Miyahara, M., Tsujii, M., Hori, M., Nakanishi, K., Kageyama, H., & Sugiyama, T. (1997). Brief report: Motor incoordination in children with Asperger’s syndrome and learning disabilities. Journal of Autism and Developmental Disorders, 27, 595–603. CrossRefPubMed
go back to reference Mostofsky, S. H., & Denckla, M. B. (2002). Excessive overflow movements on neurologic examination in children with ADHD. Annals of Neurology, 52, S127. CrossRef Mostofsky, S. H., & Denckla, M. B. (2002). Excessive overflow movements on neurologic examination in children with ADHD. Annals of Neurology, 52, S127. CrossRef
go back to reference Mostofsky, S. H., Goldberg, M. C., Landa, R. J., & Denckla, M. B. (2000). Evidence for a deficit in procedural learning in children and adolescents with autism: Implications for cerebellar contribution. Journal of the International Neuropsychological Society, 6, 752–759. CrossRefPubMed Mostofsky, S. H., Goldberg, M. C., Landa, R. J., & Denckla, M. B. (2000). Evidence for a deficit in procedural learning in children and adolescents with autism: Implications for cerebellar contribution. Journal of the International Neuropsychological Society, 6, 752–759. CrossRefPubMed
go back to reference Müller, R. A., Pierce, K., Ambrose, J. B., Allen, G., & Courchesne, E. (2001). Atypical patterns of cerebral motor activation in autism: A functional magnetic resonance study. Biological Psychiatry, 49, 665–676. CrossRefPubMed Müller, R. A., Pierce, K., Ambrose, J. B., Allen, G., & Courchesne, E. (2001). Atypical patterns of cerebral motor activation in autism: A functional magnetic resonance study. Biological Psychiatry, 49, 665–676. CrossRefPubMed
go back to reference Piek, J. P., Pitcher, T. M., & Hay, D. A. (1999). Motor coordination and kinaesthesis in boys with attention deficit-hyperactivity disorder. Developmental Medicine and Child Neurology, 41, 159–165. CrossRefPubMed Piek, J. P., Pitcher, T. M., & Hay, D. A. (1999). Motor coordination and kinaesthesis in boys with attention deficit-hyperactivity disorder. Developmental Medicine and Child Neurology, 41, 159–165. CrossRefPubMed
go back to reference Reich, W., Welner, Z., & Herjanic, B. (1997). The diagnostic interview for children and adolescents-IV. North Tonawanda: Multi-Health Systems. Reich, W., Welner, Z., & Herjanic, B. (1997). The diagnostic interview for children and adolescents-IV. North Tonawanda: Multi-Health Systems.
go back to reference Rinehart, N. J., Bradshaw, J. L., Brereton, A. V., & Tonge, B. J. (2001). Movement preparation in high-functioning autism and Asperger disorder: A serial choice reaction time task involving motor reprogramming. Journal of Autism and Developmental Disorders, 31(1), 79–88. CrossRefPubMed Rinehart, N. J., Bradshaw, J. L., Brereton, A. V., & Tonge, B. J. (2001). Movement preparation in high-functioning autism and Asperger disorder: A serial choice reaction time task involving motor reprogramming. Journal of Autism and Developmental Disorders, 31(1), 79–88. CrossRefPubMed
go back to reference Schuerholz, L. J., Cutting, L., Mazzocco, M. M. M., Singer, H. S., & Denckla, M. B. (1997). Neuromotor functioning in children with Tourette syndrome with and without attention deficit hyperactivity disorder. Journal of Child Neurology, 12(7), 438–442. PubMedCrossRef Schuerholz, L. J., Cutting, L., Mazzocco, M. M. M., Singer, H. S., & Denckla, M. B. (1997). Neuromotor functioning in children with Tourette syndrome with and without attention deficit hyperactivity disorder. Journal of Child Neurology, 12(7), 438–442. PubMedCrossRef
go back to reference Smith, I. M., & Bryson, S. E. (1994). Imitation and action in autism: A critical review. Psychological Bulletin, 116(2), 259–273. CrossRefPubMed Smith, I. M., & Bryson, S. E. (1994). Imitation and action in autism: A critical review. Psychological Bulletin, 116(2), 259–273. CrossRefPubMed
go back to reference Steger, J., Imhof, K., Coutts, E., Gundelfinger, R., Steinhausen, H. C., & Brandeis, D. (2001). Attentional and neuromotor deficits in ADHD. Developmental Medicine and Child Neurology, 43, 172–179. CrossRefPubMed Steger, J., Imhof, K., Coutts, E., Gundelfinger, R., Steinhausen, H. C., & Brandeis, D. (2001). Attentional and neuromotor deficits in ADHD. Developmental Medicine and Child Neurology, 43, 172–179. CrossRefPubMed
go back to reference Stott, D. H., Moyes, F. A., & Henderson, S. E. (1984). Manual: Test of motor impairment (Henderson Revision). Guelph: Brook International. Stott, D. H., Moyes, F. A., & Henderson, S. E. (1984). Manual: Test of motor impairment (Henderson Revision). Guelph: Brook International.
go back to reference Szatmari, P., Tuff, L., Finlayson, A. J., & Bartolucci, G. (1990). Asperger’s syndrome and autism: Neurocognitive aspects. Journal of the American Academy of Child and Adolescent Psychiatry, 29, 130–136. PubMedCrossRef Szatmari, P., Tuff, L., Finlayson, A. J., & Bartolucci, G. (1990). Asperger’s syndrome and autism: Neurocognitive aspects. Journal of the American Academy of Child and Adolescent Psychiatry, 29, 130–136. PubMedCrossRef
go back to reference Szatmari, P., Archer, L., Fisman, S., Streiner, D. L., & Wilson, F. (1995). Asperger’s syndrome and autism: Differences in behavior, cognition, and adaptive functioning. Journal of American Academy of Child and Adolescent Psychiatry, 34, 1662–1671. CrossRef Szatmari, P., Archer, L., Fisman, S., Streiner, D. L., & Wilson, F. (1995). Asperger’s syndrome and autism: Differences in behavior, cognition, and adaptive functioning. Journal of American Academy of Child and Adolescent Psychiatry, 34, 1662–1671. CrossRef
go back to reference Vilensky, J. A., Damasio, A. R., & Maurer, R. G. (1981). Gait disturbances in patients with autistic behavior: A preliminary study. Archives of Neurology, 38(10), 646–649. PubMed Vilensky, J. A., Damasio, A. R., & Maurer, R. G. (1981). Gait disturbances in patients with autistic behavior: A preliminary study. Archives of Neurology, 38(10), 646–649. PubMed
go back to reference Wechsler, D. (1974). Wechsler intelligence scale for children – revised. San Antonio, TX: The Psychological Corporation. Wechsler, D. (1974). Wechsler intelligence scale for children – revised. San Antonio, TX: The Psychological Corporation.
go back to reference Wechsler, D. (1981). Wechsler adult intelligence scale – revised. San Antonio, TX: The Psychological Corporation. Wechsler, D. (1981). Wechsler adult intelligence scale – revised. San Antonio, TX: The Psychological Corporation.
go back to reference Wechsler, D. (1991). Wechsler intelligence scale for children – III. San Antonio, TX: The Psychological Corporation. Wechsler, D. (1991). Wechsler intelligence scale for children – III. San Antonio, TX: The Psychological Corporation.
go back to reference World Health Organization. (1993). The ICD-10: DCR-10. Classification of mental and behavioural disorders: Diagnostic criteria for research. Geneva: World Health Organization. World Health Organization. (1993). The ICD-10: DCR-10. Classification of mental and behavioural disorders: Diagnostic criteria for research. Geneva: World Health Organization.
Metagegevens
Titel
Motor Signs Distinguish Children with High Functioning Autism and Asperger’s Syndrome from Controls
Auteurs
Eva M. Jansiewicz
Melissa C. Goldberg
Craig J. Newschaffer
Martha B. Denckla
Rebecca Landa
Stewart H. Mostofsky
Publicatiedatum
01-07-2006
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 5/2006
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-006-0109-y