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29-07-2016 | Original Article

Mothers’ Early Depressive Symptoms and Preschoolers’ Behavioral Problems: The Moderating Role of Genetic Influences

Auteurs: Ni Yan, Aprile Benner, Elliot Tucker-Drob, K. Paige Harden

Gepubliceerd in: Child Psychiatry & Human Development | Uitgave 3/2017

Abstract

As a stressful environment in families, mothers’ depressive symptoms might increase children’s risks of developing behavioral problems by exacerbating genetic influences. Using data from the nationally representative Early Childhood Longitudinal Study-Birth Cohort data of approximately 750 pairs of twins, we examined whether genetic influences on preschoolers’ behavioral problems depended upon mothers’ depressive symptoms. Results indicated that the genetic etiology for both internalizing and externalizing behaviors varied with maternal depressive symptoms at 9-months child age. Genetic effects on externalizing behaviors increased as mothers’ depressive symptoms increased; however, genetics effects on internalizing behaviors increased when depressive symptoms either increased or decreased from the median level. These different patterns of interactive effects suggest potentially different mechanisms for the etiology of children’s externalizing and internalizing behaviors.

vorige artikel Parenting Strategies to Deal with Children’s Anxiety: Do Parents Do What They Say They Do?

volgende artikel Parental Involvement in Cognitive Behavior Therapy for Children with Anxiety Disorders: 3-Year Follow-Up

Downey G, Coyne JC (1990) Children of depressed parents: an integrative review. Psychol Bull 108(1):50. doi:10.1037/0033-2909.108.1.50 CrossRefPubMed

Goodman SH, Rouse MH, Connell AM, Broth MR, Hall CM, Heyward D (2011) Maternal depression and child psychopathology: a meta-analytic review. Clin Child Fam Psychol Rev 14(1):1–27. doi:10.1007/s10567-010-0080-1 CrossRefPubMed

Goodman SH, Gotlib IH (1999) Risk for psychopathology in the children of depressed mothers: a developmental model for understanding mechanisms of transmission. Psychol Rev 106(3):458. doi:10.1037/0033-295x.106.3.458 CrossRefPubMed

Hayden EP, Olino TM, Bufferd SJ, Miller A, Dougherty LR, Sheikh HI, Singh SM, Klein DN (2013) The serotonin transporter linked polymorphic region and brain-derived neurotrophic factor valine to methionine at position 66 polymorphisms and maternal history of depression: associations with cognitive vulnerability to depression in childhood. Dev Psychopathol 25(03):587–598. doi:10.1017/s0954579413000035 CrossRefPubMedPubMedCentral

Deater-Deckard K, Plomin R (1999) An adoption study of the etiology of teacher and parent reports of externalizing behavior problems in middle childhood. Child Dev 70(1):144–154. doi:10.1111/1467-8624.00011 CrossRefPubMed

Oliver BR, Plomin R (2007) Twins’ Early Development Study (TEDS): a multivariate, longitudinal genetic investigation of language, cognition and behavior problems from childhood through adolescence. Twin Res Hum Genet 10(01):96–105. doi:10.1375/twin.10.1.96 CrossRefPubMed

Saudino KJ, Ronald A, Plomin R (2005) The etiology of behavior problems in 7-year-old twins: substantial genetic influence and negligible shared environmental influence for parent ratings and ratings by same and different teachers. J Abnorm Child Psychol 33(1):113–130. doi:10.1007/s10802-005-0939-7 CrossRefPubMed

Schmitz S, Fulker DW, Mrazek DA (1995) Problem behavior in early and middle childhood: an initial behavior genetic analysis. J Child Psychol Psychiatry 36(8):1443–1458. doi:10.1111/j.1469-7610.1995.tb01674.x CrossRefPubMed

van den Oord EJ, Verhulst FC, Boomsma DI (1996) A genetic study of maternal and paternal ratings of problem behaviors in 3-year-old twins. J Abnorm Psychol 105(3):349. doi:10.1037//0021-843x.105.3.349 CrossRefPubMed

10.

Arseneault L, Moffitt TE, Caspi A, Taylor A, Rijsdijk FV, Jaffee SR, Ablow JC, Measelle JR (2003) Strong genetic effects on cross-situational antisocial behavior among 5-year-old children according to mothers, teachers, examiner-observers, and twins’ self-reports. J Child Psychol Psychiatry 44(6):832–848. doi:10.1111/1469-7610.00168 CrossRefPubMed

11.

Edelbrock C, Rende R, Plomin R, Thompson LA (1995) A twin study of competence and problem behavior in childhood and early adolescence. J Child Psychol Psychiatry 36(5):775–785. doi:10.1111/j.1469-7610.1995.tb01328.x CrossRefPubMed

12.

Leve LD, Winebarger AA, Fagot BI, Reid JB, Goldsmith HH (1998) Environmental and genetic variance in children’s observed and reported maladaptive behavior. Child Dev 69(5):1286–1298. doi:10.1111/j.1467-8624.1998.tb06212.x CrossRefPubMed

13.

Zahn-Waxler C, Schmitz S, Fulker D, Robinson J, Emde R (1996) Behavior problems in 5-year-old monozygotic and dizygotic twins: genetic and environmental influences, patterns of regulation, and internalization of control. Dev Psychopathol 8(01):103–122. doi:10.1017/s0954579400006994 CrossRef

14.

Rhee SH, Waldman ID (2002) Genetic and environmental influences on antisocial behavior: a meta-analysis of twin and adoption studies. Psychol Bull 128(3):490. doi:10.1037/0033-2909.128.3.490 CrossRefPubMed

15.

Bakermans-Kranenburg MJ, Van IJzendoorn MH (2006) Gene–environment interaction of the dopamine D4 receptor (DRD4) and observed maternal insensitivity predicting externalizing behavior in preschoolers. Dev Psychobiol 48(5):406–409. doi:10.1002/dev.20152 CrossRefPubMed

16.

Fox NA, Nichols KE, Henderson HA, Rubin K, Schmidt L, Hamer D, Ernst M, Pine DS (2005) Evidence for a gene–environment interaction in predicting behavioral inhibition in middle childhood. Psychol Sci 16(12):921–926. doi:10.1111/j.1467-9280.2005.01637.x CrossRefPubMed

17.

Rutter M (2007) Gene–environment interdependence. Dev Sci 10(1):12–18. doi:10.1111/j.1467-7687.2007.00557.x CrossRefPubMed

18.

Natsuaki MN, Shaw DS, Neiderhiser JM, Ganiban JM, Harold GT, Reiss D, Leve LD (2014) Raised by depressed parents: is it an environmental risk? Clin Child Fam Psychol Rev 17(4):357–367. doi:10.1007/s10567-014-0169-z CrossRefPubMedPubMedCentral

19.

Dix T, Yan N (2014) Mothers’ depressive symptoms and infant negative emotionality in the prediction of child adjustment at age 3: testing the maternal reactivity and child vulnerability hypotheses. Dev Psychopathol 26(01):111–124. doi:10.1017/s0954579413000898 CrossRefPubMed

20.

Cheung AK, Harden KP, Tucker-Drob EM (2014) Gene × environment interactions in early externalizing behaviors: parental emotional support and socioeconomic context as moderators of genetic influences? Behav Genet 44:468–486. doi:10.1007/s10519-014-9664-8 CrossRefPubMed

21.

Dick DD, Viken R, Purcell S, Kaprio J, Pulkkinen L, Rose RJ (2007) Parental monitoring moderates the importance of genetic and environmental influences on adolescent smoking. J Abnorm Psychol 116:213–218. doi:10.1037/0021-843x.116.1.213 CrossRefPubMedPubMedCentral

22.

Davidge KM, Atkinson L, Douglas L, Lee V, Shapiro S, Kennedy JL, Beitchman JH (2004) Association of the serotonin transporter and 5HT1Dβ receptor genes with extreme, persistent and pervasive aggressive behaviour in children. Psychiatr Genet 14(3):143–146. doi:10.1097/00041444-200409000-00004 CrossRefPubMed

23.

Haberstick BC, Lessem JM, Hopfer CJ, Smolen A, Ehringer MA, Timberlake D, Hewitt JK (2005) Monoamine oxidase A (MAOA) and antisocial behaviors in the presence of childhood and adolescent maltreatment. Am J Med Genet Part B Neuropsychiatr Genet 135(1):59–64. doi:10.1002/ajmg.b.30176 CrossRef

24.

South SC, Krueger RF (2013) Marital satisfaction and physical health: evidence for an orchid effect. Psychol Sci 24(3):373–378. doi:10.1177/0956797612453116 CrossRefPubMedPubMedCentral

25.

Tucker-Drob EM, Rhemtulla M, Harden KP, Turkheimer E, Fask D (2011) Emergence of a gene × socioeconomic status interaction on infant mental ability between 10 months and 2 years. Psychol Sci 22(1):125–133. doi:10.1177/0956797610392926 CrossRefPubMed

26.

Monroe SM, Simons AD (1991) Diathesis–stress theories in the context of life stress research: implications for the depressive disorders. Psychol Bull 110(3):406. doi:10.1037//0033-2909.110.3.406 CrossRefPubMed

27.

Belsky J, Pluess M (2009) Beyond diathesis stress: differential susceptibility to environmental influences. Psychol Bull 135(6):885. doi:10.1037/a0017376 CrossRefPubMed

28.

Boyce WT, Ellis BJ (2005) Biological sensitivity to context: I. An evolutionary-developmental theory of the origins and functions of stress reactivity. Dev Psychopathol 17(02):271–301. doi:10.1017/s0954579405050145 CrossRefPubMed

29.

Kochanska G, Kim S, Barry RA, Philibert RA (2011) Stress or differential susceptibility? children’s genotypes interact with maternal responsive care in predicting children’s competence: diathesis–stress or differential susceptibility? Dev Psychopathol 23(2):605–616. doi:10.1017/s0954579411000071 CrossRefPubMedPubMedCentral

30.

Bethel J, Green JL, Nord C, Kalton G, West J (2005) Early childhood longitudinal study, birth cohort (ECLS-B): methodology report for the 9-month data collection (2001–02), vol 2: Sampling, NCES 2005-147. National Center for Education Statistics

31.

Forget-Dubois N, Pérusse D, Turecki G, Girard A, Billette JM, Rouleau G, Malo J, Tremblay RE (2003) Diagnosing zygosity in infant twins: physical similarity, genotyping, and chorionicity. Twin Res 6(06):479–485. doi:10.1375/136905203322686464 CrossRefPubMed

32.

Radloff LS (1977) The CES-D scale a self-report depression scale for research in the general population. Appl Psychol Meas 1(3):385–401. doi:10.1177/014662167700100306 CrossRef

33.

Merrell KW (2002) Preschool and Kindergarten Behaviour Rating Scales (PKBS-2). PRO-ED, Austin. doi:10.1590/1678-7153.201427409

34.

Prescott CA (2004) Using the Mplus computer program to estimate models for continuous and categorical data from twins. Behav Genet 34(1):17–40. doi:10.1023/b:bege.0000009474.97649.2f CrossRefPubMed

35.

Muthen LK, Muthen B (2012) 1998–2012. Mplus user’s guide, 7th edn. Muthen & Muthen, Los Angeles

36.

Cummings EM, Davies PT (1994) Maternal depression and child development. J Child Psychol Psychiatry 35(1):73–122. doi:10.1080/0300443870270103 CrossRefPubMed

37.

Yan N, Dix T (2014) Mothers’ early depressive symptoms and children’s first-grade adjustment: a transactional analysis of child withdrawal as a mediator. J Child Psychol Psychiatry 55(5):495–504. doi:10.1111/jcpp.12189 CrossRefPubMed

38.

Bergen SE, Gardner CO, Kendler KS (2007) Age-related changes in heritability of behavioral phenotypes over adolescence and young adulthood: a meta-analysis. Twin Res Hum Genet 10(03):423–433. doi:10.1375/twin.10.3.423 CrossRefPubMed

39.

Stanger C, Lewis M (1993) Agreement among parents, teachers, and children on internalizing and externalizing behavior problems. J Clin Child Psychol 22:107–116. doi:10.1207/s15374424jccp2201_11 CrossRef

40.

Ellis BJ, Boyce WT (2008) Biological sensitivity to context. Curr Dir Psychol Sci 17(3):183–187. doi:10.1111/j.1467-8721.2008.0057.x CrossRef

41.

O’Connor TG, McGuire S, Reiss D, Hetherington EM, Plomin R (1998) Co-occurrence of depressive symptoms and antisocial behavior in adolescence: a common genetic liability. J Abnorm Psychol 107(1):27. doi:10.1037/0021-843x.107.1.27 CrossRefPubMed

42.

Gjone H, Stevenson J (1997) The association between internalizing and externalizing behavior in childhood and early adolescence: genetic or environmental common influences? J Abnorm Child Psychol 25(4):277–286. doi:10.1037/0021-843X.107.1.27 CrossRefPubMed

Titel: Mothers’ Early Depressive Symptoms and Preschoolers’ Behavioral Problems: The Moderating Role of Genetic Influences
Auteurs: Ni Yan
Aprile Benner
Elliot Tucker-Drob
K. Paige Harden
Publicatiedatum: 29-07-2016
Uitgeverij: Springer US
Gepubliceerd in: Child Psychiatry & Human Development / Uitgave 3/2017
Print ISSN: 0009-398X
Elektronisch ISSN: 1573-3327
DOI: https://doi.org/10.1007/s10578-016-0669-9

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