Skip to main content
Top
Gepubliceerd in: Quality of Life Research 11/2018

14-07-2018

Modelling a preference-based index for EQ-5D using a non-parametric Bayesian method

Auteurs: Samer A. Kharroubi, Chaza Abou Daher

Gepubliceerd in: Quality of Life Research | Uitgave 11/2018

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

Background

Conventionally, models used for health state valuation data have been parametric. Recently, a number of researchers have investigated the use of non-parametric Bayesian methods in this area.

Objectives

In this paper, we present a non-parametric Bayesian model to estimate a preference-based index for a five-dimensional health state classification, namely EQ-5D.

Methods

A sample of 2997 members of the UK general population valued 43 health states selected from a total of 243 health states defined by the EQ-5D using time trade-off technique. Findings from non-parametric modelling are reported in this paper and compared to previously used parametric estimations. The impact of respondent characteristics on health state valuations is also reported.

Results

The non-parametric models were found to be better at predicting scores in populations with different distributions of characteristics than observed in the survey sample. Additionally, non-parametric models were found to be better at allowing for the impact of respondent characteristics to vary by health state. The results show an important age effect with sex having some effect.

Conclusion

The non-parametric Bayesian models provide more realistic and better utility estimates from the EQ-5D than previously used parametric models have done. Furthermore, the model is more flexible in estimating the impact of covariates.
Bijlagen
Alleen toegankelijk voor geautoriseerde gebruikers
Literatuur
1.
go back to reference Brooks, R. (1996). EuroQol: The current state of play. Health Policy, 37, 53–72.CrossRef Brooks, R. (1996). EuroQol: The current state of play. Health Policy, 37, 53–72.CrossRef
2.
go back to reference Torrance, G. W., Feeny, D. H., Furlong, W. J., Barr, R. D., Zhang, Y., & Wang, Q. A. (1996). Multi-attribute utility function for a comprehensive health status classification system: Health Utilities Index Mark 2. Medical Care, 34(7), 702–722.CrossRef Torrance, G. W., Feeny, D. H., Furlong, W. J., Barr, R. D., Zhang, Y., & Wang, Q. A. (1996). Multi-attribute utility function for a comprehensive health status classification system: Health Utilities Index Mark 2. Medical Care, 34(7), 702–722.CrossRef
3.
go back to reference Feeny, D. H., Furlong, W. J., Torrance, G. W., Goldsmith, C. H., Zenglong, Z., Depauw, S., Denton, M., & Boyle, M. (2002). Multi-attribute and single-attribute utility function for the Health Utility Index Mark 3 system. Medical Care, 40(20), 113–128.CrossRef Feeny, D. H., Furlong, W. J., Torrance, G. W., Goldsmith, C. H., Zenglong, Z., Depauw, S., Denton, M., & Boyle, M. (2002). Multi-attribute and single-attribute utility function for the Health Utility Index Mark 3 system. Medical Care, 40(20), 113–128.CrossRef
4.
go back to reference Sintonen, H. (1994). The 15D-measure of health-related quality of life. I. Reliability, validity and sensitivity of its health state descriptive system. National Center for Health Program Evaluation 1994; Working Paper 41, Melbourne. Sintonen, H. (1994). The 15D-measure of health-related quality of life. I. Reliability, validity and sensitivity of its health state descriptive system. National Center for Health Program Evaluation 1994; Working Paper 41, Melbourne.
5.
go back to reference Sintonen, H. (1995). The 15D-measure of health-related quality of life. II. Feasibility, reliability and validity of its valuation system. National Center for Health Program Evaluation 1995; Working Paper 42, Melbourne. Sintonen, H. (1995). The 15D-measure of health-related quality of life. II. Feasibility, reliability and validity of its valuation system. National Center for Health Program Evaluation 1995; Working Paper 42, Melbourne.
6.
go back to reference Hawthorne, G., Richardson, G., & Atherton_Day, N. (2001). A comparison of the assessment of quality of life (AQoL) with four other generic utility instruments. Annals of Medicine, 33, 358–370.CrossRef Hawthorne, G., Richardson, G., & Atherton_Day, N. (2001). A comparison of the assessment of quality of life (AQoL) with four other generic utility instruments. Annals of Medicine, 33, 358–370.CrossRef
7.
go back to reference Kaplan, R. M., & Anderson, J. P. (1988). A general health policy model: Update and application. Health Services Research, 23, 203–235.PubMedPubMedCentral Kaplan, R. M., & Anderson, J. P. (1988). A general health policy model: Update and application. Health Services Research, 23, 203–235.PubMedPubMedCentral
8.
go back to reference Brazier, J. E., Roberts, J., & Deverill, M. (2002). The estimation of a preference-based measure of health from the SF-36. Journal of Health Economics, 21, 271–292.CrossRef Brazier, J. E., Roberts, J., & Deverill, M. (2002). The estimation of a preference-based measure of health from the SF-36. Journal of Health Economics, 21, 271–292.CrossRef
9.
go back to reference Revicki, D. A., Leidy, N. K., Brennan-Diemer, F., Sorenson, S., & Togias, A. (1998). Integrating patients’ preferences into health outcomes assessment: The multiattribute asthma symptom utility index. Chest, 114(4), 998–1007.CrossRef Revicki, D. A., Leidy, N. K., Brennan-Diemer, F., Sorenson, S., & Togias, A. (1998). Integrating patients’ preferences into health outcomes assessment: The multiattribute asthma symptom utility index. Chest, 114(4), 998–1007.CrossRef
10.
go back to reference Brazier, J. E., Czoski-Murray, C., Roberts, J., Brown, M., Symonds, T., & Kelleher, C. (2008). Estimation of a preference-based index from a condition specific measure: The King’s Health Questionnaire. Medical Decision Making, 28, 113–126.CrossRef Brazier, J. E., Czoski-Murray, C., Roberts, J., Brown, M., Symonds, T., & Kelleher, C. (2008). Estimation of a preference-based index from a condition specific measure: The King’s Health Questionnaire. Medical Decision Making, 28, 113–126.CrossRef
11.
go back to reference Brazier, J. E., Ratcliffe, J., Tsuchiya, A., & Solomon, J. (2007). Measuring and valuing health for economic evaluation. Oxford: Oxford University Press. Brazier, J. E., Ratcliffe, J., Tsuchiya, A., & Solomon, J. (2007). Measuring and valuing health for economic evaluation. Oxford: Oxford University Press.
12.
go back to reference Drummond, M. F., Sculpher, M., O’Brien, B., & Stoddart, G. L. (2005). Torrance, G.W: Methods for the economic evaluation of health care programmes. Oxford: Oxford Medical Publications. Drummond, M. F., Sculpher, M., O’Brien, B., & Stoddart, G. L. (2005). Torrance, G.W: Methods for the economic evaluation of health care programmes. Oxford: Oxford Medical Publications.
13.
go back to reference Dolan, P. (1997). Modeling valuation for Euroqol health states. Medical Care, 35, 351–363.CrossRef Dolan, P. (1997). Modeling valuation for Euroqol health states. Medical Care, 35, 351–363.CrossRef
14.
go back to reference McCabe, C., Stevens, K., Roberts, J., & Brazier, J. E. (2005). Health state values for the HUI2 descriptive system: results from a UK Survey. Health Economics, 14, 231–244.CrossRef McCabe, C., Stevens, K., Roberts, J., & Brazier, J. E. (2005). Health state values for the HUI2 descriptive system: results from a UK Survey. Health Economics, 14, 231–244.CrossRef
15.
go back to reference Kharroubi, S. A., O’Hagan, A., & Brazier, J. E. (2005). Estimating Utilities from individual health state preference data: A nonparametric Bayesian approach. Applied Statistics, 54, 879–895. Kharroubi, S. A., O’Hagan, A., & Brazier, J. E. (2005). Estimating Utilities from individual health state preference data: A nonparametric Bayesian approach. Applied Statistics, 54, 879–895.
16.
go back to reference Kharroubi, S. A., Brazier, J., O’Hagan, A., & Roberts, J. (2007). Modelling SF-6D health state preference data using a nonparametric Bayesian method. Journal of Health Economics, 26, 597–612.CrossRef Kharroubi, S. A., Brazier, J., O’Hagan, A., & Roberts, J. (2007). Modelling SF-6D health state preference data using a nonparametric Bayesian method. Journal of Health Economics, 26, 597–612.CrossRef
17.
go back to reference Kharroubi, S. A., Brazier, J., O’Hagan, A., & Roberts, J. (2007). Modelling covariates for the SF-6D standard gamble health state preference data using a nonparametric Bayesian method. Social Science & Medicine, 64, 1242–1252.CrossRef Kharroubi, S. A., Brazier, J., O’Hagan, A., & Roberts, J. (2007). Modelling covariates for the SF-6D standard gamble health state preference data using a nonparametric Bayesian method. Social Science & Medicine, 64, 1242–1252.CrossRef
18.
go back to reference Kharroubi, S. A., & McCabe, C. (2008). Modelling HUI 2 health state preference data using a nonparametric Bayesian method. Medical Decision Making, 28, 875–887.CrossRef Kharroubi, S. A., & McCabe, C. (2008). Modelling HUI 2 health state preference data using a nonparametric Bayesian method. Medical Decision Making, 28, 875–887.CrossRef
19.
go back to reference Dolan, P., Gudex, C., & Kind, P. (1996). Valuing health states: A comparison of methods. Journal of Health Economics, 2, 209–232.CrossRef Dolan, P., Gudex, C., & Kind, P. (1996). Valuing health states: A comparison of methods. Journal of Health Economics, 2, 209–232.CrossRef
20.
go back to reference Shaw, J. W., Johnson, J. A., & Coons, S. J. (2005). US valuation of the EQ-5D health states: Development and testing of the D1 valuation model. Medical Care, 43, 203–220.CrossRef Shaw, J. W., Johnson, J. A., & Coons, S. J. (2005). US valuation of the EQ-5D health states: Development and testing of the D1 valuation model. Medical Care, 43, 203–220.CrossRef
23.
go back to reference Oakley, J., & O’Hagan, A. (2002). Bayesian inference for the uncertainty distribution of computer model outputs. Biometrika, 89, 769–784.CrossRef Oakley, J., & O’Hagan, A. (2002). Bayesian inference for the uncertainty distribution of computer model outputs. Biometrika, 89, 769–784.CrossRef
Metagegevens
Titel
Modelling a preference-based index for EQ-5D using a non-parametric Bayesian method
Auteurs
Samer A. Kharroubi
Chaza Abou Daher
Publicatiedatum
14-07-2018
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 11/2018
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-018-1935-z

Andere artikelen Uitgave 11/2018

Quality of Life Research 11/2018 Naar de uitgave