Top

Tip

Swipe om te navigeren naar een ander artikel

Gepubliceerd in:

01-03-2010 | Original Paper

Mindfulness-Based Stress Reduction in Oncology: Evaluating Mindfulness and Rumination as Mediators of Change in Depressive Symptoms

Auteurs: Laura E. Labelle, Tavis S. Campbell, Linda E. Carlson

Gepubliceerd in: Mindfulness | Uitgave 1/2010

Abstract

Mindfulness-Based Stress Reduction (MBSR), an 8-week group psychosocial intervention, has received increasing research support for its efficacy in oncology settings. Changes associated with MBSR participation for people with cancer include improved psychological functioning and quality of life. However, as with other populations, it remains unclear which components of MBSR bring about change and whether targeted constructs are critical in changing outcomes. We propose a mediation model to be tested as a first step towards understanding program mechanisms. Specifically, changes in mindfulness and rumination were hypothesized to mediate the impact of MBSR participation on symptoms of depression in people living with cancer. A waitlist-controlled study of MBSR participation in 77 women who had completed cancer treatment was conducted to test this model. Pre- to post-program, MBSR participants improved significantly more on depressive symptoms and mindfulness and decreased more on rumination scores compared to waiting controls. Decreases in rumination mediated the impact of MBSR on depressive symptoms, but mindfulness scores did not. Methodological recommendations are presented to promote research that will further elucidate the mechanisms of action of MBSR. Mediation analyses will inform the next generation of randomized controlled trials and may lead to program modifications that will maximize the effectiveness and efficiency of mindfulness-based interventions in cancer settings.

vorige artikel State Effects of Two Forms of Meditation on Prefrontal EEG Asymmetry in Previously Depressed Individuals

volgende artikel Searching for Mindfulness in the Brain: A Process-Oriented Approach to Examining the Neural Correlates of Mindfulness

Adler, N. E., Page, A., National Institute of Medicine, & Committee on Psychosocial Services to Cancer Patients / Families in a Community Setting. (2008). Cancer care for the whole patient: Meeting psychosocial health needs. Washington DC: National Academies Press.

Amato, J. J., Williams, M., Greenberg, C., Bar, M., Lo, S., & Tepler, I. (1998). Psychological support to an autologous bone marrow transplant unit in a community hospital: A pilot experience. Psycho-Oncology, 7(2), 121–125. PubMedCrossRef

Andresen, E. M., Malmgren, J. A., Carter, W. B., & Patrick, D. L. (1994). Screening for depression in well older adults: Evaluation of a short form of the CES-D (center for epidemiologic studies depression scale). American Journal of Preventive Medicine, 10(2), 77–84. PubMed

Astin, J. A. (1997). Stress reduction through mindfulness meditation: effects on psychological symptomatology, sense of control, and spiritual experiences. Psychotherapy and Psychosomatics, 66, 97–106. PubMedCrossRef

Baer, R. A. (2003). Mindfulness training as clinical intervention: A conceptual and empirical review. Clinical Psychology: Science and Practice, 10, 125–143. CrossRef

Baer, R. A., Smith, G. T., Lykins, E., Button, D., Krietemeyer, J., Sauer, S., et al. (2008). Construct validity of the five facet mindfulness questionnaire in meditating and nonmeditating samples. Assessment, 15, 329–342. PubMedCrossRef

Baron, R. M., & Kenny, D. A. (1986). The moderator-mediator variable distinction in social psychological research: Conceptual, strategic and statistical considerations. Journal of Personality and Social Psychology, 51, 1173–1182. PubMedCrossRef

Bishop, S. R., Lau, M., Shapiro, S., Carlson, L., Anderson, N. D., Carmody, J. F., et al. (2004). Mindfulness: A proposed operational definition. Clinical Psychology: Science & Practice, 11, 230–241. CrossRef

Boey, K. W. (1999). Cross-validation of a short form of the CES-D in Chinese elderly. International Journal of Geriatric Psychiatry, 14(8), 608–617. PubMedCrossRef

Bonadona, V., Saltel, P., Desseigne, F., Mignotte, H., Saurin, J. C., Wang, Q., et al. (2002). Cancer patients who experienced diagnostic genetic testing for cancer susceptibility: Reactions and behavior after the disclosure of a positive test result. Cancer Epidemiology, Biomarkers and Prevention, 11(1), 97–104. PubMed

Bower, J. E. (2008). Behavioral symptoms in patients with breast cancer and survivors. Journal of Clinical Oncology, 26(5), 768–777. PubMedCrossRef

Bredart, A., Autier, P., Audisio, R. A., & Geragthy, J. (1998). Psycho-social aspects of breast cancer susceptibility testing: A literature review. European Journal of Cancer Care (Engl.), 7(3), 174–180. CrossRef

Brown, K. W., & Ryan, R. M. (2003). The benefits of being present: Mindfulness and its role in psychological well-being. Journal of Personality and Social Psychology, 84, 822–848. PubMedCrossRef

Cameron, L. D., & Diefenbach, M. A. (2001). Responses to information about psychosocial consequences of genetic testing for breast cancer susceptibility: Influences of cancer worry and risk perceptions. Journal of Health Psychology, 6(1), 47–59. CrossRef

Carlson, L. E., & Brown, K. W. (2005). Validation of the mindful attention awareness scale in a cancer population. Journal of Psychosomatic Research, 58, 29–33. PubMedCrossRef

Carlson, L. E., & Garland, S. N. (2005). Impact of mindfulness-based stress reduction (MBSR) on sleep, mood, stress and fatigue symptoms in cancer outpatients. International Journal of Behavioral Medicine, 12, 278–285. PubMedCrossRef

Carlson, L. E., Labelle, L. E., Garland, S. N., Hutchins, M. L., & Birnie, K. (2009). Mindfulness-based interventions in oncology. In F. Didonna (Ed.), Clinical handbook of mindfulness (pp. 383–404). New York: Springer. CrossRef

Carlson, L. E., & Speca, M. (2010). Mindfulness-based cancer recovery: A step-by-step MBSR approach to help you cope with treatment and reclaim your life. Oakville: New Harbinger. In Press.

Carlson, L. E., Speca, M., Patel, K. D., & Faris, P. (2007). One year pre-post intervention follow-up of psychological, immune, endocrine and blood pressure outcomes of mindfulness-based stress reduction (MBSR) in breast and prostate cancer outpatients. Brain, Behavior, and Immunity, 21, 1038–1049. PubMedCrossRef

Carlson, L. E., Speca, M., Patel, K. D., & Goodey, E. (2003). Mindfulness-based stress reduction in relation to quality of life, mood, symptoms of stress, and immune parameters in breast and prostate cancer outpatients. Psychosomatic Medicine, 65(4), 571–581. PubMedCrossRef

Carlson, L. E., Speca, M., Patel, K. D., & Goodey, E. (2004). Mindfulness-based stress reduction in relation to quality of life, mood, symptoms of stress and levels of cortisol, dehydroepiandrosterone sulfate (DHEAS) and melatonin in breast and prostate cancer outpatients. Psychoneuroendocrinology, 29(4), 448–474. PubMedCrossRef

Carlson, L. E., Ursuliak, Z., Goodey, E., Angen, M., & Speca, M. (2001). The effects of a mindfulness meditation based stress reduction program on mood and symptoms of stress in cancer outpatients: Six month follow-up. Supportive Care in Cancer, 9, 112–123. PubMedCrossRef

Carmody, J., & Baer, R. A. (2008). Relationships between mindfulness practice and levels of mindfulness, medical and psychological symptoms and well-being in a mindfulness-based stress reduction program. Journal of Behavioral Medicine, 31, 23–33. PubMedCrossRef

Carmody, J., Baer, R. A., Lykins, E. L. B., & Olendzki, N. (2009). An empirical study of the mechanisms of mindfulness in a mindfulness-based stress reduction program. Journal of Clinical Psychology, 65(6), 613–626. PubMedCrossRef

Chambers, R., Gullone, E., & Allen, N. B. (2009). Mindful emotion regulation: An integrative review. Clinical Psychology Review, 29(6), 560–572. PubMedCrossRef

Cheng, S. T., & Chan, A. C. (2005). The center for epidemiologic studies depression scale in older Chinese: Thresholds for long and short forms. International Journal of Geriatric Psychiatry, 20(5), 465–470. PubMedCrossRef

Cohen, J. (1977). Statistical power analysis for the behavioral sciences (revisedth ed.). New York: Academic.

Cohen, J. (1988). Statistical power analysis for the behavioral sciences, 2nd ed. Hillsdale, NJ: Erlbaum.

Dimeo, F., Bertz, H., Finke, J., Fetscher, S., Mertelsmann, R., & Keul, J. (1996). An aerobic exercise program for patients with haematological malignancies after bone marrow transplantation. Bone Marrow Transplantation, 18(6), 1157–1160. PubMed

Dobkin, P. L. (2008). Mindfulness-based stress reduction: What processes are at work? Complementary Therapies in Clinical Practice, 14(1), 8–16. PubMedCrossRef

Epstein, M. (1995). Thoughts without a thinker: Psychotherapy from a Buddhist perspective. New York: Basic Books.

Fritz, M. S., & Mackinnon, D. P. (2007). Required sample size to detect the mediated effect. Psychological Science, 18(3), 233–239. PubMedCrossRef

Garland, S. N., Carlson, L. E., Cook, S., Lansdell, L., & Speca, M. (2007). A non-randomized comparison of mindfulness-based stress reduction and healing arts programs for facilitating post-traumatic growth and spirituality in cancer outpatients. Supportive Care in Cancer, 15(8), 949–961. PubMedCrossRef

Germer, C. K. (2005). Mindfulness: What is it? what does it matter? In C. K. Germer, R. D. Siegel, & P. R. Fulton (Eds.), Mindfulness and psychotherapy (pp. 3–27). New York: Guilford.

Gross, J. J. (1998). The emerging field of emotion regulation: An integrative review. Review of General Psychology, 2(3), 271–299. CrossRef

Hopwood, P. (1997). Psychological issues in cancer genetics: Current research and future priorities. Patient Education and Counselling, 32(1–2), 19–31. CrossRef

Hopwood, P., Keeling, F., Long, A., Pool, C., Evans, G., & Howell, A. (1998). Psychological support needs for women at high genetic risk of breast cancer: Some preliminary indicators. Psycho-Oncology, 7(5), 402–412. PubMedCrossRef

Horner, M. J., Ries, L. A. G., Krapcho, M., Neyman, N., Aminou, R., Howlader, N., et al. (2009). SEER cancer statistics review, 1975–2006. Bethesda: National Cancer Institute.

Jain, S., Shapiro, S. L., Swanick, S., Roesch, S. C., Mills, P. J., Bell, I., et al. (2007). A randomized controlled trial of mindfulness meditation versus relaxation training: Effects on distress, positive states of mind, rumination, and distraction. Annals of Behavioral Medicine, 33(1), 11–21. PubMedCrossRef

Kabat-Zinn, J. (1982). An outpatient program in behavioral medicine for chronic pain patients based on the practice of mindfulness meditation: Theoretical considerations and preliminary results. General Hospital Psychiatry, 4, 33–47. PubMedCrossRef

Kabat-Zinn, J. (1990). Full catastrophe living: Using the wisdom of your body and mind to face stress, pain and illness. New York: Delacourt.

Kash, K. M., Holland, J. C., Halper, M. S., & Miller, D. G. (1992). Psychological distress and surveillance behaviors of women with a family history of breast cancer. Journal of the National Cancer Institute, 84(1), 24–30. PubMedCrossRef

Keller, M. (2000). Psychosocial issues in cancer genetics: State of the art. Zeitschrift fur Psychosomatische Medizin und Psychoanalyse, 46(1), 80–97.

Kim, Y. S., Jun, H., Chae, Y., Park, H. J., Kim, B. H., Chang, I. M., et al. (2005). The practice of Korean medicine: An overview of clinical trials in acupuncture. Evidence-Based Complementary and Alternative Medicine, 2(3), 325–352. PubMedCrossRef

Kraemer, H. C., Wilson, G. T., Fairburn, C. G., & Agras, W. S. (2002). Mediators and moderators of treatment effects in randomized clinical trials. Archives of General Psychiatry, 59(10), 877–883. PubMedCrossRef

Kramer, J. H., Crittenden, M. R., DeSantes, K., & Cowan, M. J. (1997). Cognitive and adaptive behavior 1 and 3 years following bone marrow transplantation. Bone Marrow Transplantation, 19(6), 607–613. PubMedCrossRef

Lamanque, P., & Daneault, S. (2006). Does meditation improve the quality of life for patients living with cancer? Canadian Family Physician Medecin De Famille Canadien, 52, 474–475. PubMed

Lasry, J. C., Margolese, R. G., Poisson, R., Shibata, H., Fleischer, D., Lafleur, D., et al. (1987). Depression and body image following mastectomy and lumpectomy. Journal of Chronic Diseases, 40(6), 529–534. PubMedCrossRef

Lau, M. A., Bishop, S. R., Segal, Z. V., Buis, T., Anderson, N. D., Carlson, L., et al. (2006). The Toronto mindfulness scale: Development and validation. Journal of Clinical Psychology, 62(12), 1445–1467. PubMedCrossRef

Ledesma, D., & Kumano, H. (2009). Mindfulness-based stress reduction and cancer: A meta-analysis. Psycho-Oncology, 18(571), 579.

Lengacher, C. A., Johnson-Mallard, V., Post-White, J., Moscoso, M. S., Jacobson, P. B., Klein, T. W., et al. (2009). Randomized controlled trial of mindfulness-based stress reduction (MBSR) for survivors of breast cancer. Psycho-Oncology, 18(12), 1261–1272. PubMedCrossRef

Lerman, C., Daly, M., Sands, C., Balshem, A., Lustbader, E., Heggan, T., et al. (1993). Mammography adherence and psychological distress among women at risk for breast cancer. Journal of the National Cancer Institute, 85(13), 1074–1080. PubMedCrossRef

Lerman, C., Lustbader, E., Rimer, B., Daly, M., Miller, S., Sands, C., et al. (1995). Effects of individualized breast cancer risk counseling: A randomized trial. Journal of the National Cancer Institute, 87(4), 286–292. PubMedCrossRef

Lerman, C., & Schwartz, M. (1993). Adherence and psychological adjustment among women at high risk for breast cancer. Breast Cancer Research and Treatment, 28(2), 145–155. PubMedCrossRef

Ma, S. H., & Teasdale, J. D. (2004). Mindfulness-based cognitive therapy for depression: Replication and exploration of differential relapse prevention effects. Journal of Consulting & Clinical Psychology, 72(1), 31–40. CrossRef

Mackenzie, M. J., Carlson, L. E., Munoz, M., & Speca, M. (2007). A qualitative study of self-perceived effects of mindfulness-based stress reduction (MBSR) in a psychosocial oncology setting. Stress and Health: Journal of the International Society for the Investigation of Stress, 23(1), 59–69.

Mackenzie, M. J., Carlson, L. E., & Speca, M. (2005). Mindfulness-based stress reduction (MBSR) in oncology: Rationale and review. Evidence Based Integrative Medicine, 2, 139–145. CrossRef

MacKinnon, D. P. (2008). Introduction to statistical mediation analysis. New York: Erlbaum.

MacKinnon, D. P., Lockwood, C. M., Hoffman, J. M., West, S. G., & Sheets, V. (2002). A comparison of methods to test mediation and other intervening variable effects. Psychological Methods, 7(1), 83–104. PubMedCrossRef

MacKinnon, D. P., Lockwood, C. M., & Williams, J. (2004). Confidence limits for the indirect effect: Distribution of the product and resampling methods. Multivariate Behavioral Research, 39(1), 99–128. PubMedCrossRef

Matchim, Y., & Armer, J. M. (2007). Measuring the psychological impact of mindfulness meditation on health among patients with cancer: A literature review. Oncology Nursing Forum, 34(5), 1059–1066. PubMedCrossRef

Morris, S. B., & DeShon, R. P. (2002). Combining effect size estimates in meta-analysis with repeated measures and independent-groups designs. Psychological Methods, 7(1), 105–125. PubMedCrossRef

Mullens, A. B., McCaul, K. D., Erickson, S. C., & Sandgren, A. K. (2004). Coping after cancer: Risk perceptions, worry, and health behaviors among colorectal cancer survivors. Psycho-Oncology, 13(6), 367–376. PubMedCrossRef

National Institute of Mental Health. (2002). Psychotherapeutic interventions: How and why they work. Bethesda: National Institute of Mental Health.

Norman, G. R., Sloan, J. A., Wyrwich, K. W., & Norman, G. R. (2003). Interpretation of changes in health-related quality of life: The remarkable universality of half a standard deviation. Medical Care, 41, 582–592. PubMedCrossRef

Nyklicek, I., & Kuijpers, K. F. (2008). Effects of mindfulness-based stress reduction intervention on psychological well-being and quality of life: Is increased mindfulness indeed the mechanism? Annals of Behavioral Medicine, 35(3), 331–340. PubMedCrossRef

Onitilo, A. A., Nietert, P. J., & Egede, L. E. (2006). Effect of depression on all-cause mortality in adults with cancer and differential effects by cancer site. General Hospital Psychiatry, 28(5), 396–402. PubMedCrossRef

Ott, M. J., Norris, R. L., & Bauer-Wu, S. M. (2006). Mindfulness meditation for oncology patients. Integrative Cancer Therapies, 5, 98–108. PubMedCrossRef

Preacher, K. J., & Hayes, A. F. (2004). SPSS and SAS procedures for estimating indirect effects in simple mediation models. Behavior Research Methods, Instruments, & Computers, 36(4), 717–731.

Preacher, K. J., & Hayes, A. F. (2008). Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models. Behavior Research Methods, 40(3), 879–891. PubMedCrossRef

Prieto, J. M., Atala, J., Blanch, J., Carreras, E., Rovira, M., Cirera, E., et al. (2005). Role of depression as a predictor of mortality among cancer patients after stem-cell transplantation. Journal of Clinical Oncology, 23(25), 6063–6071. PubMedCrossRef

Radloff, L. S. (1977). The CES-D scale: A self-report depression scale for research in the general population. Applied Psychological Measurement, 1, 385–401. CrossRef

Ramel, W., Goldin, P. R., Carmona, P. E., & McQuaid, J. R. (2004). The effects of mindfulness meditation on cognitive processes and affect in patients with past depression. Cognitive Therapy and Research, 28, 433–455. CrossRef

Rosnow, R. L., & Rosenthal, R. (1996). Computing contrasts, effect sizes, and counternulls on other people's published data: General procedures for research consumers. Psychological Methods, 1(4), 331–340. CrossRef

Satin, J. R., Linden, W., & Phillips, M. J. (2009). Depression as a predictor of disease progression and mortality in cancer patients: A meta-analysis. Cancer, 115(22), 5349–5361. PubMedCrossRef

Segal, Z. V., Bizzini, L., & Bondolfi, G. (2005). Cognitive behaviour therapy reduces long term risk of relapse in recurrent major depressive disorder. Evidence Based Mental Health, 8, 38. PubMedCrossRef

Segal, Z. V., Williams, M. G., & Teasdale, J. D. (2002). Mindfulness-based cognitive therapy for depression: A new approach to preventing relapse. New York: Guilford.

Shapiro, S. L., & Carlson, L. E. (2009). The art and science of mindfulness: Integrating mindfulness into psychology and the helping professions. Washington DC: American Psychological Association. CrossRef

Shapiro, S. L., Carlson, L. E., Astin, J. A., & Freedman, B. (2006). Mechanisms of mindfulness. Journal of Clinical Psychology, 62, 373–386. PubMedCrossRef

Shapiro, S. L., Oman, D., Thoresen, C. E., Plante, T. G., & Flinders, T. (2008). Cultivating mindfulness: Effects on well-being. Journal of Clinical Psychology, 64(7), 840–862. PubMedCrossRef

Shapiro, S. L., Schwartz, G. E., & Bonner, G. (1998). Effects of mindfulness-based stress reduction on medical and premedical students. Journal of Behavioral Medicine, 21, 581–599. PubMedCrossRef

Shrout, P. E., & Bolger, N. (2002). Mediation in experimental and nonexperimental studies: New procedures and recommendations. Psychological Methods, 7(4), 422–445. PubMedCrossRef

Smith, J. E., Richardson, J., Hoffman, C., & Pilkington, K. (2005). Mindfulness-based stress reduction as supportive therapy in cancer care: Systematic review. Journal of Advanced Nursing, 52, 315–327. PubMedCrossRef

Spahn, G., Lehmann, N., Franken, U., Paul, A., Longhorst, J., Michalsen, A., et al. (2003). Improvement of fatigue and role function of cancer patients after an outpatient integrative mind-body intervention. Focus on Alternative and Complementary Therapies, 8(4), 540.

Speca, M., Carlson, L. E., Goodey, E., & Angen, M. (2000). A randomized, wait-list controlled clinical trial: The effect of a mindfulness meditation-based stress reduction program on mood and symptoms of stress in cancer outpatients. Psychosomatic Medicine, 62(5), 613–622. PubMed

Speca, M., Carlson, L. E., Mackenzie, M. J., & Angen, M. (2006). Mindfulness-based stress reduction (MBSR) as an intervention for cancer patients. In R. A. Baer (Ed.), Mindfulness-based treatment approaches: A clinician's guide to evidence base and approaches (pp. 239–261). Burlington: Elsevier.

Spiegel, D., & Giese-Davis, J. (2003). Depression and cancer: Mechanisms and disease progression. Biological Psychiatry, 54, 269–282. PubMedCrossRef

Teasdale, J. D., & Green, H. A. (2004). Ruminative self-focus and autobiographical memory. Personality & Individual Differences, 36, 1933–1943. CrossRef

Teasdale, J. D., Segal, Z. V., Williams, J. M., Ridgeway, V. A., Soulsby, J. M., & Lau, M. A. (2000). Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Journal of Consulting and Clinical Psychology, 68, 615–623. PubMedCrossRef

Temoshok, L. R. (2000). Psychological response and survival in breast cancer. Lancet, 355(920), 404–405. PubMedCrossRef

Temoshok, L. R., & Wald, R. L. (2002). Change is complex: Rethinking research on psychosocial interventions and cancer. Integrative Cancer Therapies, 1(2), 135–145. PubMedCrossRef

Trapnell, P. D., & Campbell, J. D. (1999). Private self-consciousness and the five-factor model of personality: Distinguishing rumination from reflection. Journal of Personality & Social Psychology, 76, 284–304. CrossRef

Van Wielingen, L. E., Carlson, L. E., & Campbell, T. S. (2007). Mindfulness-based stress reduction (MBSR), blood pressure, and psychological functioning in women with cancer. Psychosomatic Medicine, 69, A43.

Verhoef, M. J., Casebeer, A. L., & Hilsden, R. J. (2002). Assessing efficacy of complementary medicine: Adding qualitative research methods to the "gold standard". Journal of Alternative and Complementary Medicine, 8(3), 275–281. CrossRef

Vickers, A. J. (1996). Can acupuncture have specific effects on health? A systematic review of acupuncture antiemesis trials. Journal of the Royal Society of Medicine, 89(6), 303–311. PubMed

Vickers, A. J. (2004). Statistical reanalysis of four recent randomized trials of acupuncture for pain using analysis of covariance. Clinical Journal of Pain, 20(5), 319–323. PubMedCrossRef

Vickers, A. J., Rees, R. W., Zollman, C. E., McCarney, R., Smith, C. M., Ellis, N., et al. (2004). Acupuncture of chronic headache disorders in primary care: Randomised controlled trial and economic analysis. Health Technology Assessment, 8(48), 1–35.

Watanabe, S., & Bruera, E. (1996). Anorexia and cachexia, asthenia, and lethargy. Hematology/oncology Clinics of North America, 10(1), 189–206. PubMedCrossRef

Watson, M., Haviland, J. S., Greer, S., Davidson, J., & Bliss, J. M. (1999). Influence of psychological response on survival in breast cancer: A population-based cohort study. Lancet, 354(9187), 1331–1336. PubMedCrossRef

Watson, M., Homewood, J., Haviland, J., & Bliss, J. M. (2005). Influence of psychological response on breast cancer survival: 10-year follow-up of a population-based cohort. European Journal of Cancer, 41(12), 1710–1714. PubMedCrossRef

Wetzel, W. (1989). Reiki healing: A physiologic perspective. Journal of Holistic Nursing, 7(1), 47–54. CrossRef

White, A., & Ernst, E. (2003). Pitfalls in conducting systematic reviews of acupuncture. Rheumatology (Oxford, England), 42(10), 1271–1272. CrossRef

White, A., & Ernst, E. (2004). A brief history of acupuncture. Rheumatology (Oxford, England), 43(5), 662–663. CrossRef

Williams, K. A., Kolar, M. M., Reger, B. E., & Pearson, J. C. (2001). Evaluation of a wellness-based mindfulness stress reduction intervention: A controlled trial. American Journal of Health Promotion, 15, 422–432. PubMed

Witek-Janusek, L., Albuquerque, K., Chroniak, K. R., Chroniak, C., Durazo-Arvizu, R., & Mathews, H. L. (2008). Effect of mindfulness based stress reduction on immune function, quality of life and coping in women newly diagnosed with early stage breast cancer. Brain, Behavior, & Immunity, 22(6), 969–981. CrossRef

Wonderling, D., Vickers, A. J., Grieve, R., & McCarney, R. (2004). Cost effectiveness analysis of a randomised trial of acupuncture for chronic headache in primary care. BMJ, 328(7442), 747. PubMedCrossRef

Yano, K., Kanie, T., Okamoto, S., Kojima, H., Yoshida, T., Maruta, I., et al. (2000). Quality of life in adult patients after stem cell transplantation. International Journal of Hematology, 71(3), 283–289. PubMed

Titel: Mindfulness-Based Stress Reduction in Oncology: Evaluating Mindfulness and Rumination as Mediators of Change in Depressive Symptoms
Auteurs: Laura E. Labelle
Tavis S. Campbell
Linda E. Carlson
Publicatiedatum: 01-03-2010
Uitgeverij: Springer US
Gepubliceerd in: Mindfulness / Uitgave 1/2010
Print ISSN: 1868-8527
Elektronisch ISSN: 1868-8535
DOI: https://doi.org/10.1007/s12671-010-0005-6

Bohn Stafleu van Loghum

Tip

Swipe om te navigeren naar een ander artikel

Deel dit onderdeel of sectie (kopieer de link)

Abstract

Log in om toegang te krijgen

Andere artikelen Uitgave 1/2010

Factors Associated with Attrition from Mindfulness-Based Cognitive Therapy in Patients with a History of Suicidal Depression

State Effects of Two Forms of Meditation on Prefrontal EEG Asymmetry in Previously Depressed Individuals

Mindfulness in Forensic Mental Health: Does It Have a Role?

Mindfulness: A Finger Pointing to the Moon

Shauna L. Shapiro and Linda E. Carlson: The Art and Science of Mindfulness: Integrating Mindfulness into Psychology and the Helping Professions

Searching for Mindfulness in the Brain: A Process-Oriented Approach to Examining the Neural Correlates of Mindfulness