Skip to main content
Top
Gepubliceerd in: Journal of Behavioral Medicine 5/2021

07-05-2021

Mindfulness-based stress reduction for breast cancer survivors (MBSR(BC)): evaluating mediators of psychological and physical outcomes in a large randomized controlled trial

Auteurs: Cecile A. Lengacher, L. Forest Gruss, Kevin E. Kip, Richard R. Reich, Katterine G. Chauca, Manolete S. Moscoso, Anisha Joshi, Sara Tinsley, Budhrani Shani, Lakeshia Cousin, Carly Paterson Khan, Matthew Goodman, Jong Y. Park

Gepubliceerd in: Journal of Behavioral Medicine | Uitgave 5/2021

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

MBSR(BC) is known to have a positive impact on psychological and physical symptoms among breast cancer survivors (BCS). The cognitive mechanisms of “how” MBSR(BC) works was addressed in a recent study that found that there was strong consistent evidence that reduced emotional reactivity is a mediator and moderate consistent evidence that mindfulness, rumination, and worry were mediators. The purpose of this study, as part of a larger R01 trial, was to test whether positive effects achieved from the MBSR(BC) program were mediated through changes in increased mindfulness, decreased fear of breast cancer recurrence, and perceived stress. Female BCS > 21 years diagnosed with Stage 0-III breast cancer were randomly assigned to a 6-week MBSR(BC) or a Usual Care (UC)regimen. Potential mediators of 6- and 12-week outcomes were identified by analysis of covariance (ANCOVA), followed by formal mediational analyses of main effects of MBSR(BC) on 6- and 12-week outcomes, including percentage of total effects explained. Among 322 BCS (167 MBSR(BC) and 155 UC), fear of recurrence and perceived stress, but not mindfulness, mediated reductions in anxiety and fatigue at weeks 6 and 12, partially supporting our hypothesis of cognitive mechanisms of MBSR(BC).

Trial Registration

Registration Number: NCT01177124 http://​www.​ClinicalTrials.​gov
Literatuur
go back to reference American Cancer Society (2019). Cancer Facts & Figures. In American Cancer Society (Ed.). Atlanta. American Cancer Society (2019). Cancer Facts & Figures. In American Cancer Society (Ed.). Atlanta.
go back to reference Baer, R. A., Lykins, E., & Peters, J. R. (2012). Mindfulness and self-compassion as predictors of psychological wellbeing in long-term meditators and matched nonmeditators. The Journal of Positive Psychology, 7, 230–238.CrossRef Baer, R. A., Lykins, E., & Peters, J. R. (2012). Mindfulness and self-compassion as predictors of psychological wellbeing in long-term meditators and matched nonmeditators. The Journal of Positive Psychology, 7, 230–238.CrossRef
go back to reference Baer, R. A., Smith, G. T., Hopkins, J., Krietemeyer, J., & Toney, L. (2006). Using self-report assessment methods to explore facets of mindfulness. Assessment, 13, 27–45.PubMedCrossRef Baer, R. A., Smith, G. T., Hopkins, J., Krietemeyer, J., & Toney, L. (2006). Using self-report assessment methods to explore facets of mindfulness. Assessment, 13, 27–45.PubMedCrossRef
go back to reference Baer, R. A., Smith, G. T., Lykins, E., Button, D., Krietemeyer, J., Sauer, S., & Williams, J. M. (2008). Construct validity of the five facet mindfulness questionnaire in meditating and nonmeditating samples. Assessment, 15, 329–342.PubMedCrossRef Baer, R. A., Smith, G. T., Lykins, E., Button, D., Krietemeyer, J., Sauer, S., & Williams, J. M. (2008). Construct validity of the five facet mindfulness questionnaire in meditating and nonmeditating samples. Assessment, 15, 329–342.PubMedCrossRef
go back to reference Bishop, S. R., Lau, M., Shapiro, S., Carlson, L., Anderson, N. D., Carmody, J., & Devins, G. (2004). Mindfulness: A proposed operational definition. Clinical Psychology Science and Practice, 11, 230–241.CrossRef Bishop, S. R., Lau, M., Shapiro, S., Carlson, L., Anderson, N. D., Carmody, J., & Devins, G. (2004). Mindfulness: A proposed operational definition. Clinical Psychology Science and Practice, 11, 230–241.CrossRef
go back to reference Boden, M. T., Bernstein, A., Walser, R. D., Bui, L., Alvarez, J., & Bonn-Miller, M. O. (2012). Changes in facets of mindfulness and posttraumatic stress disorder treatment outcome. Psychiatry Research, 200(2–3), 609–613.CrossRef Boden, M. T., Bernstein, A., Walser, R. D., Bui, L., Alvarez, J., & Bonn-Miller, M. O. (2012). Changes in facets of mindfulness and posttraumatic stress disorder treatment outcome. Psychiatry Research, 200(2–3), 609–613.CrossRef
go back to reference Boyle, C. C., Stanton, A. L., Ganz, P. A., Crespi, C. M., & Bower, J. E. (2017). Improvements in emotion regulation following mindfulness meditation: Effects on depressive symptoms and perceived stress in younger breast cancer survivors. Journal of Consulting and Clinical Psychology, 85, 397.PubMedPubMedCentralCrossRef Boyle, C. C., Stanton, A. L., Ganz, P. A., Crespi, C. M., & Bower, J. E. (2017). Improvements in emotion regulation following mindfulness meditation: Effects on depressive symptoms and perceived stress in younger breast cancer survivors. Journal of Consulting and Clinical Psychology, 85, 397.PubMedPubMedCentralCrossRef
go back to reference Bränström, R., Kvillemo, P., Brandberg, Y., & Moskowitz, J. T. (2010). Self-report mindfulness as a mediator of psychological well-being in a stress reduction intervention for cancer patients- A randomized study. Annals of Behavioral Medicine, 39, 151–161.PubMedCrossRef Bränström, R., Kvillemo, P., Brandberg, Y., & Moskowitz, J. T. (2010). Self-report mindfulness as a mediator of psychological well-being in a stress reduction intervention for cancer patients- A randomized study. Annals of Behavioral Medicine, 39, 151–161.PubMedCrossRef
go back to reference Bränström, R., Kvillemo, P., & Moskowitz, J. T. (2012). A randomized study of the effects of mindfulness training on psychological well-being and symptoms of stress in patients treated for cancer at 6-month follow-up. International journal of behavioral medicine, 19, 535–542.PubMedPubMedCentralCrossRef Bränström, R., Kvillemo, P., & Moskowitz, J. T. (2012). A randomized study of the effects of mindfulness training on psychological well-being and symptoms of stress in patients treated for cancer at 6-month follow-up. International journal of behavioral medicine, 19, 535–542.PubMedPubMedCentralCrossRef
go back to reference Brown, K. W., & Cordon, S. (2009). Toward a Phenomenology of Mindfulness: Subjective Experience and Emotional Correlates. In F. Didonna (Ed.), Clinical Handbook of Mindfulness. New York: Springer Science. Brown, K. W., & Cordon, S. (2009). Toward a Phenomenology of Mindfulness: Subjective Experience and Emotional Correlates. In F. Didonna (Ed.), Clinical Handbook of Mindfulness. New York: Springer Science.
go back to reference Brown, K. W., Ryan, R. A., & Creswell, J. D. (2007). Mindfulness: Theoretical foundations and evidence for its salutary effects. Psychological Inquiry, 18(4), 211–237. Retrieved from <Go to ISI>://000250865000001 Brown, K. W., Ryan, R. A., & Creswell, J. D. (2007). Mindfulness: Theoretical foundations and evidence for its salutary effects. Psychological Inquiry, 18(4), 211–237. Retrieved from <Go to ISI>://000250865000001
go back to reference Butow, P. N., Turner, J., Gilchrist, J., Sharpe, L., Smith, A. B., Fardell, J. E., & Gebski, V. J. (2017). Randomized trial of ConquerFear: A novel, theoretically based psychosocial intervention for fear of cancer recurrence. Journal of Clinical Oncology, 35, 4066–4077.PubMedCrossRef Butow, P. N., Turner, J., Gilchrist, J., Sharpe, L., Smith, A. B., Fardell, J. E., & Gebski, V. J. (2017). Randomized trial of ConquerFear: A novel, theoretically based psychosocial intervention for fear of cancer recurrence. Journal of Clinical Oncology, 35, 4066–4077.PubMedCrossRef
go back to reference Campbell, T. S., Labelle, L. E., Bacon, S. L., Faris, P., & Carlson, L. E. (2012). Impact of mindfulness-based stress reduction (MBSR) on attention, rumination and resting blood pressure in women with cancer: A waitlist-controlled study. Journal of Behavioral Medicine, 35, 262–271.PubMedCrossRef Campbell, T. S., Labelle, L. E., Bacon, S. L., Faris, P., & Carlson, L. E. (2012). Impact of mindfulness-based stress reduction (MBSR) on attention, rumination and resting blood pressure in women with cancer: A waitlist-controlled study. Journal of Behavioral Medicine, 35, 262–271.PubMedCrossRef
go back to reference Carlson, L. E., Doll, R., Stephen, J., Faris, P., Tamagawa, R., Drysdale, E., & Speca, M. (2013). Randomized controlled trial of mindfulness-based cancer recovery versus supportive expressive group therapy for distressed survivors of breast cancer (MINDSET). Journal of Clinical Oncology, 31, 3119–3126. https://doi.org/10.1200/jco.2012.47.5210.CrossRefPubMed Carlson, L. E., Doll, R., Stephen, J., Faris, P., Tamagawa, R., Drysdale, E., & Speca, M. (2013). Randomized controlled trial of mindfulness-based cancer recovery versus supportive expressive group therapy for distressed survivors of breast cancer (MINDSET). Journal of Clinical Oncology, 31, 3119–3126. https://​doi.​org/​10.​1200/​jco.​2012.​47.​5210.CrossRefPubMed
go back to reference Cheli, S., Caligiani, L., Martella, F., De Bartolo, P., Mancini, F., & Fioretto, L. (2019). Mindfulness and metacognition in facing with fear of recurrence: A proof-of-concept study with breast-cancer women. Psycho-oncology, 28, 600–606.PubMed Cheli, S., Caligiani, L., Martella, F., De Bartolo, P., Mancini, F., & Fioretto, L. (2019). Mindfulness and metacognition in facing with fear of recurrence: A proof-of-concept study with breast-cancer women. Psycho-oncology, 28, 600–606.PubMed
go back to reference Compen, F., Bisseling, E., Schellekens, M., Donders, R., Carlson, L., van der Lee, M., & Speckens, A. (2018). Face-to-face and internet-based mindfulness-based cognitive therapy compared with treatment as usual in reducing psychological distress in patients with cancer: A multicenter randomized controlled trial. Journal of Clinical Oncology, 36, 2413–2421.PubMedCrossRef Compen, F., Bisseling, E., Schellekens, M., Donders, R., Carlson, L., van der Lee, M., & Speckens, A. (2018). Face-to-face and internet-based mindfulness-based cognitive therapy compared with treatment as usual in reducing psychological distress in patients with cancer: A multicenter randomized controlled trial. Journal of Clinical Oncology, 36, 2413–2421.PubMedCrossRef
go back to reference Crane-Okada, R., Kiger, H., Sugerman, F., Uman, G. C., Shapiro, S. L., Wyman-McGinty, W., & Anderson, N. L. (2012). Mindful movement program for older breast cancer survivors: A pilot study. Cancer Nursing, 35, E1–E13.PubMed Crane-Okada, R., Kiger, H., Sugerman, F., Uman, G. C., Shapiro, S. L., Wyman-McGinty, W., & Anderson, N. L. (2012). Mindful movement program for older breast cancer survivors: A pilot study. Cancer Nursing, 35, E1–E13.PubMed
go back to reference DeSantis, C. E., Ma, J., Gaudet, M. M., Newman, L. A., Miller, K. D., Goding Sauer, A., & Siegel, R. L. (2019). Breast cancer statistics. CA A Cancer J Clin, 69, 438–451.CrossRef DeSantis, C. E., Ma, J., Gaudet, M. M., Newman, L. A., Miller, K. D., Goding Sauer, A., & Siegel, R. L. (2019). Breast cancer statistics. CA A Cancer J Clin, 69, 438–451.CrossRef
go back to reference Feldman, G., Hayes, A., Kumar, S., Greeson, J., & Laurenceau, J. (2007). Mindfulness and emotion regulation: The development and initial validation of the cognitive and affective mindfulness scale-revised (CAMS-R). Journal of Psychopathology and Behavioral Assessment, 29, 177–190.CrossRef Feldman, G., Hayes, A., Kumar, S., Greeson, J., & Laurenceau, J. (2007). Mindfulness and emotion regulation: The development and initial validation of the cognitive and affective mindfulness scale-revised (CAMS-R). Journal of Psychopathology and Behavioral Assessment, 29, 177–190.CrossRef
go back to reference Garland, S. N., Carlson, L. E., Stephens, A. J., Antle, M. C., Samuels, C., & Campbell, T. S. (2014). Mindfulness-based stress reduction compared with cognitive behavioral therapy for the treatment of insomnia comorbid with cancer: a randomized, partially blinded, noninferiority trial. Journal of Clinical Oncology, 32, 449–457.PubMedCrossRef Garland, S. N., Carlson, L. E., Stephens, A. J., Antle, M. C., Samuels, C., & Campbell, T. S. (2014). Mindfulness-based stress reduction compared with cognitive behavioral therapy for the treatment of insomnia comorbid with cancer: a randomized, partially blinded, noninferiority trial. Journal of Clinical Oncology, 32, 449–457.PubMedCrossRef
go back to reference Gu, J., Strauss, C., Bond, R., & Cavanagh, K. (2015). How do mindfulness-based cognitive therapy and mindfulness-based stress reduction improve mental health and wellbeing? A systematic review and meta-analysis of mediation studies. Clinical Psychology Review, 37, 1–12.CrossRefPubMed Gu, J., Strauss, C., Bond, R., & Cavanagh, K. (2015). How do mindfulness-based cognitive therapy and mindfulness-based stress reduction improve mental health and wellbeing? A systematic review and meta-analysis of mediation studies. Clinical Psychology Review, 37, 1–12.CrossRefPubMed
go back to reference Hall, D. L., Luberto, C. M., Philpotts, L. L., Song, R., Park, E. R., & Yeh, G. Y. (2018). Mind-body interventions for fear of cancer recurrence: A systematic review and meta-analysis. Psycho-oncology, 27, 2546–2558.PubMedPubMedCentralCrossRef Hall, D. L., Luberto, C. M., Philpotts, L. L., Song, R., Park, E. R., & Yeh, G. Y. (2018). Mind-body interventions for fear of cancer recurrence: A systematic review and meta-analysis. Psycho-oncology, 27, 2546–2558.PubMedPubMedCentralCrossRef
go back to reference Hamilton, N. A., Kitzman, H., & Guyotte, S. (2006). Enhancing health and emotion: Mindfulness as a missing link between cognitive therapy and positive psychology. Journal of Cognitive Psychotherapy, 20, 123–134.CrossRef Hamilton, N. A., Kitzman, H., & Guyotte, S. (2006). Enhancing health and emotion: Mindfulness as a missing link between cognitive therapy and positive psychology. Journal of Cognitive Psychotherapy, 20, 123–134.CrossRef
go back to reference Hann, D. M., Jacobsen, P., Martin, S., Azzarello, L., & Greenberg, H. (1998). Fatigue and quality of life following radiotherapy for breast cancer: A comparative study. Journal of Clinical Psychology in Medical Settings, 5, 19–33.CrossRef Hann, D. M., Jacobsen, P., Martin, S., Azzarello, L., & Greenberg, H. (1998). Fatigue and quality of life following radiotherapy for breast cancer: A comparative study. Journal of Clinical Psychology in Medical Settings, 5, 19–33.CrossRef
go back to reference Hayes, S., Luoma, J., Bond, F., Masuda, A., & Lillis, J. (2006). Behaviour research and therapy. Behaviour Research and Therapy, 44, 1–25.PubMedCrossRef Hayes, S., Luoma, J., Bond, F., Masuda, A., & Lillis, J. (2006). Behaviour research and therapy. Behaviour Research and Therapy, 44, 1–25.PubMedCrossRef
go back to reference Hicks, R., & Tingley, D. (2011). Causal mediation analysis. Stata J, 11, 605.CrossRef Hicks, R., & Tingley, D. (2011). Causal mediation analysis. Stata J, 11, 605.CrossRef
go back to reference Hölzel, B. K., Lazar, S. W., Gard, T., Schuman-Olivier, Z., Vago, D. R., & Ott, U. (2011). How does mindfulness meditation work? Proposing mechanisms of action from a conceptual and neural perspective. Perspectives on Psychological Science, 6, 537–559.PubMedCrossRef Hölzel, B. K., Lazar, S. W., Gard, T., Schuman-Olivier, Z., Vago, D. R., & Ott, U. (2011). How does mindfulness meditation work? Proposing mechanisms of action from a conceptual and neural perspective. Perspectives on Psychological Science, 6, 537–559.PubMedCrossRef
go back to reference Jain, S., Shapiro, S. L., Swanick, S., Roesch, S. C., Mills, P. J., Bell, I., & Schwartz, G. E. (2007). A randomized controlled trial of mindfulness meditation versus relaxation training: Effects on distress, positive states of mind, rumination, and distraction. Annuals of Behavioral Medicine, 33, 11–21. https://doi.org/10.1207/s15324796abm3301_2.CrossRef Jain, S., Shapiro, S. L., Swanick, S., Roesch, S. C., Mills, P. J., Bell, I., & Schwartz, G. E. (2007). A randomized controlled trial of mindfulness meditation versus relaxation training: Effects on distress, positive states of mind, rumination, and distraction. Annuals of Behavioral Medicine, 33, 11–21. https://​doi.​org/​10.​1207/​s15324796abm3301​_​2.CrossRef
go back to reference Johns, S. A., Brown, L. F., Beck-Coon, K., Monahan, P. O., Tong, Y., & Kroenke, K. (2015). Randomized controlled pilot study of mindfulness-based stress reduction for persistently fatigued cancer survivors. Psycho-Oncology, 24, 885–893.PubMedCrossRef Johns, S. A., Brown, L. F., Beck-Coon, K., Monahan, P. O., Tong, Y., & Kroenke, K. (2015). Randomized controlled pilot study of mindfulness-based stress reduction for persistently fatigued cancer survivors. Psycho-Oncology, 24, 885–893.PubMedCrossRef
go back to reference Josefsson, T., Larsman, P., Broberg, A., & Lundh, L.-G. (2011). Self-reported mindfulness mediates the relation between meditation experience and psychological well-being. Mindfulness, 2, 49–58.CrossRef Josefsson, T., Larsman, P., Broberg, A., & Lundh, L.-G. (2011). Self-reported mindfulness mediates the relation between meditation experience and psychological well-being. Mindfulness, 2, 49–58.CrossRef
go back to reference Kabat-Zinn, J. (1990). Full-catastrophe living: Using the wisdom of your body and mind to face stress, pain and illness. . Bantam Doubleday Dell Publishing. Kabat-Zinn, J. (1990). Full-catastrophe living: Using the wisdom of your body and mind to face stress, pain and illness. . Bantam Doubleday Dell Publishing.
go back to reference Kabat-Zinn, J. (2003). Mindfulness-based interventions in context: Past, present, and future. Clinical Psychology-Science and Practice, 10, 144–156.CrossRef Kabat-Zinn, J. (2003). Mindfulness-based interventions in context: Past, present, and future. Clinical Psychology-Science and Practice, 10, 144–156.CrossRef
go back to reference Kabat-Zinn, J., Massion, A. O., Kristeller, J., Peterson, L. G., Fletcher, K. E., Pbert, L., . . . Santorelli, S. F. (1992). Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders. American Journal of Psychiatry, 149(7), 936–943. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/1609875 Kabat-Zinn, J., Massion, A. O., Kristeller, J., Peterson, L. G., Fletcher, K. E., Pbert, L., . . . Santorelli, S. F. (1992). Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders. American Journal of Psychiatry, 149(7), 936–943. Retrieved from http://​www.​ncbi.​nlm.​nih.​gov/​pubmed/​1609875
go back to reference Kazdin, A. E. (2006). Mechanisms of Change in Psychotherapy: Advances, Breakthroughs, and Cutting-Edge Research (Do Not Yet Exist). Kazdin, A. E. (2006). Mechanisms of Change in Psychotherapy: Advances, Breakthroughs, and Cutting-Edge Research (Do Not Yet Exist).
go back to reference Kim, M. K., Lee, K. S., Kim, B., Choi, T. K., & Lee, S.-H. (2016). Impact of mindfulness-based cognitive therapy on intolerance of uncertainty in patients with panic disorder. Psychiatry investigation, 13, 196.PubMedPubMedCentralCrossRef Kim, M. K., Lee, K. S., Kim, B., Choi, T. K., & Lee, S.-H. (2016). Impact of mindfulness-based cognitive therapy on intolerance of uncertainty in patients with panic disorder. Psychiatry investigation, 13, 196.PubMedPubMedCentralCrossRef
go back to reference Kraemer, H., Wilson, T., Fairburn, C. C. G., & Agras, W. S. (2002). Mediators and moderators of treatment effects in randomized clinical trials. Archives of General Psychiatry, 59, 877–883.PubMedCrossRef Kraemer, H., Wilson, T., Fairburn, C. C. G., & Agras, W. S. (2002). Mediators and moderators of treatment effects in randomized clinical trials. Archives of General Psychiatry, 59, 877–883.PubMedCrossRef
go back to reference Labelle, L. E., Campbell, T. S., & Carlson, L. E. (2010). Mindfulness-based stress reduction in oncology: Evaluating mindfulness and rumination as mediators of change in depressive symptoms. Mindfulness, 1, 28–40.CrossRef Labelle, L. E., Campbell, T. S., & Carlson, L. E. (2010). Mindfulness-based stress reduction in oncology: Evaluating mindfulness and rumination as mediators of change in depressive symptoms. Mindfulness, 1, 28–40.CrossRef
go back to reference Labelle, L. E., Lawlor-Savage, L., Campbell, T. S., Faris, P., & Carlson, L. E. (2015). Does self-report mindfulness mediate the effect of Mindfulness-Based Stress Reduction (MBSR) on spirituality and posttraumatic growth in cancer patients? The Journal of Positive Psychology, 10, 153–166.CrossRef Labelle, L. E., Lawlor-Savage, L., Campbell, T. S., Faris, P., & Carlson, L. E. (2015). Does self-report mindfulness mediate the effect of Mindfulness-Based Stress Reduction (MBSR) on spirituality and posttraumatic growth in cancer patients? The Journal of Positive Psychology, 10, 153–166.CrossRef
go back to reference Laurenceau, J.-P., Hayes, A. M., & Feldman, G. C. (2007). Some methodological and statistical issues in the study of change processes in psychotherapy. Clinical Psychology Review, 27, 682–695.PubMedPubMedCentralCrossRef Laurenceau, J.-P., Hayes, A. M., & Feldman, G. C. (2007). Some methodological and statistical issues in the study of change processes in psychotherapy. Clinical Psychology Review, 27, 682–695.PubMedPubMedCentralCrossRef
go back to reference Lengacher, C. A., Johnson-Mallard, V., Barta, M., Fitzgerald, S., Moscoso, M. S., Post-White, J., & Kip, K. E. (2011). Feasibility of a mindfulness-based stress reduction program for early-stage breast cancer survivors. Journal of Holistic Nursing, 29, 107–117.PubMedCrossRef Lengacher, C. A., Johnson-Mallard, V., Barta, M., Fitzgerald, S., Moscoso, M. S., Post-White, J., & Kip, K. E. (2011). Feasibility of a mindfulness-based stress reduction program for early-stage breast cancer survivors. Journal of Holistic Nursing, 29, 107–117.PubMedCrossRef
go back to reference Lengacher, C. A., Johnson-Mallard, V., Post-White, J., Moscoso, M. S., Jacobsen, P. B., Klein, T. W., & Kip, K. E. (2009). Randomized controlled trial of mindfulness-based stress reduction (MBSR) for survivors of breast cancer. Psycho-Oncology, 18, 1261–1272.PubMedCrossRef Lengacher, C. A., Johnson-Mallard, V., Post-White, J., Moscoso, M. S., Jacobsen, P. B., Klein, T. W., & Kip, K. E. (2009). Randomized controlled trial of mindfulness-based stress reduction (MBSR) for survivors of breast cancer. Psycho-Oncology, 18, 1261–1272.PubMedCrossRef
go back to reference Lengacher, C. A., Reich, R., Post-White, J., Moscoso, M., Shelton, M., Barta, M., & Budhrani, P. (2012). Mindfulness based stress reduction in post-treatment breast cancer patients: An examination of symptoms and symptom clusters. Journal of Behavioral Medicine, 35, 86–94.PubMedCrossRef Lengacher, C. A., Reich, R., Post-White, J., Moscoso, M., Shelton, M., Barta, M., & Budhrani, P. (2012). Mindfulness based stress reduction in post-treatment breast cancer patients: An examination of symptoms and symptom clusters. Journal of Behavioral Medicine, 35, 86–94.PubMedCrossRef
go back to reference Lengacher, C. A., Reich, R. R., Paterson, C. L., Jim, H. S., Ramesar, S., Alinat, C. B., & Kip, K. E. (2015). The effects of mindfulness-based stress reduction on objective and subjective sleep parameters in women with breast cancer: A randomized controlled trial. Psycho-Oncology, 24, 424–43.PubMedCrossRef Lengacher, C. A., Reich, R. R., Paterson, C. L., Jim, H. S., Ramesar, S., Alinat, C. B., & Kip, K. E. (2015). The effects of mindfulness-based stress reduction on objective and subjective sleep parameters in women with breast cancer: A randomized controlled trial. Psycho-Oncology, 24, 424–43.PubMedCrossRef
go back to reference Lengacher, C. A., Reich, R. R., Paterson, C. L., Ramesar, S., Park, J. Y., Alinat, C. B., & Kip, K. E. (2016). Examination of broad symptom improvement due to mindfulness-based stress reduction for breast cancer survivors: A randomized controlled trial. Journal of Clinical Oncology, 37, 2827–2834.CrossRef Lengacher, C. A., Reich, R. R., Paterson, C. L., Ramesar, S., Park, J. Y., Alinat, C. B., & Kip, K. E. (2016). Examination of broad symptom improvement due to mindfulness-based stress reduction for breast cancer survivors: A randomized controlled trial. Journal of Clinical Oncology, 37, 2827–2834.CrossRef
go back to reference Lengacher, C. A., Shelton, M. M., Reich, R. R., Barta, M. K., Johnson-Mallard, V., Moscoso, M. S., & Kip, K. E. (2014). Mindfulness based stress reduction (MBSR(BC)) in breast cancer: Evaluating fear of recurrence (FOR) as a mediator of psychological and physical symptoms in a randomized control trial (RCT). Journal of Behavioral Medicine, 37, 185–195.PubMedCrossRef Lengacher, C. A., Shelton, M. M., Reich, R. R., Barta, M. K., Johnson-Mallard, V., Moscoso, M. S., & Kip, K. E. (2014). Mindfulness based stress reduction (MBSR(BC)) in breast cancer: Evaluating fear of recurrence (FOR) as a mediator of psychological and physical symptoms in a randomized control trial (RCT). Journal of Behavioral Medicine, 37, 185–195.PubMedCrossRef
go back to reference Moyer, A., Goldenberg, M., Hall, M. A., Knapp-Oliver, S. K., Sohl, S. J., Sarma, E. A., & Schneider, S. (2012). Mediators of change in psychosocial interventions for cancer patients: A systematic review. Behavioral Medicine, 38, 90–114.PubMedCrossRef Moyer, A., Goldenberg, M., Hall, M. A., Knapp-Oliver, S. K., Sohl, S. J., Sarma, E. A., & Schneider, S. (2012). Mediators of change in psychosocial interventions for cancer patients: A systematic review. Behavioral Medicine, 38, 90–114.PubMedCrossRef
go back to reference O’Bryan, E. M., Luberto, C. M., Kraemer, K. M., & McLeish, A. C. (2018). An examination of mindfulness skills in terms of affect tolerance among individuals with elevated levels of health anxiety. Anxiety, Stress, & Coping, 31, 702–713.CrossRef O’Bryan, E. M., Luberto, C. M., Kraemer, K. M., & McLeish, A. C. (2018). An examination of mindfulness skills in terms of affect tolerance among individuals with elevated levels of health anxiety. Anxiety, Stress, & Coping, 31, 702–713.CrossRef
go back to reference Preacher, K. J., & Hayes, A. F. (2004). SPSS and SAS procedures for estimating indirect effects in simple mediation models. Behavior Research Methods, Instruments, & Computers, 36, 717–731.CrossRef Preacher, K. J., & Hayes, A. F. (2004). SPSS and SAS procedures for estimating indirect effects in simple mediation models. Behavior Research Methods, Instruments, & Computers, 36, 717–731.CrossRef
go back to reference Radloff, L. (1977). The CES-D scale: A self-report depression scale for researching the general population. Application of Psychological Measures, 1, 385–401.CrossRef Radloff, L. (1977). The CES-D scale: A self-report depression scale for researching the general population. Application of Psychological Measures, 1, 385–401.CrossRef
go back to reference Reich, R. R., Lengacher, C. A., Alinat, C. B., Kip, K. E., Paterson, C., Ramesar, S., & Moscoso, M. (2017). Mindfulness-based stress reduction in post-treatment breast cancer patients: Immediate and sustained effects across multiple symptom clusters. Journal of Pain and Symptom Management, 53, 85–95.PubMedCrossRef Reich, R. R., Lengacher, C. A., Alinat, C. B., Kip, K. E., Paterson, C., Ramesar, S., & Moscoso, M. (2017). Mindfulness-based stress reduction in post-treatment breast cancer patients: Immediate and sustained effects across multiple symptom clusters. Journal of Pain and Symptom Management, 53, 85–95.PubMedCrossRef
go back to reference Spielberger, C., Gorsuch, R., & Luschene, R. (1983). Manual for the State-Trait Anxiety Inventory. . Consulting Psychologists. Spielberger, C., Gorsuch, R., & Luschene, R. (1983). Manual for the State-Trait Anxiety Inventory. . Consulting Psychologists.
go back to reference Ware, J. H., Kosinski, M., & Keller, M. (1994). SF-36 physical and mental health summary scales, a user’s manual. (2nd ed.). The Health Institute. Ware, J. H., Kosinski, M., & Keller, M. (1994). SF-36 physical and mental health summary scales, a user’s manual. (2nd ed.). The Health Institute.
go back to reference Xu, W., Zhou, Y., Fu, Z., & Rodriguez, M. (2017). Relationships between dispositional mindfulness, self-acceptance, perceived stress, and psychological symptoms in advanced gastrointestinal cancer patients. Psycho-oncology, 26, 2157–2161.PubMedCrossRef Xu, W., Zhou, Y., Fu, Z., & Rodriguez, M. (2017). Relationships between dispositional mindfulness, self-acceptance, perceived stress, and psychological symptoms in advanced gastrointestinal cancer patients. Psycho-oncology, 26, 2157–2161.PubMedCrossRef
go back to reference Zainal, N. Z., Booth, S., & Huppert, F. A. (2013). The efficacy of mindfulness-based stress reduction on mental health of breast cancer patients: A meta-analysis. Psycho-Oncology, 22, 1457–1465.PubMedCrossRef Zainal, N. Z., Booth, S., & Huppert, F. A. (2013). The efficacy of mindfulness-based stress reduction on mental health of breast cancer patients: A meta-analysis. Psycho-Oncology, 22, 1457–1465.PubMedCrossRef
Metagegevens
Titel
Mindfulness-based stress reduction for breast cancer survivors (MBSR(BC)): evaluating mediators of psychological and physical outcomes in a large randomized controlled trial
Auteurs
Cecile A. Lengacher
L. Forest Gruss
Kevin E. Kip
Richard R. Reich
Katterine G. Chauca
Manolete S. Moscoso
Anisha Joshi
Sara Tinsley
Budhrani Shani
Lakeshia Cousin
Carly Paterson Khan
Matthew Goodman
Jong Y. Park
Publicatiedatum
07-05-2021
Uitgeverij
Springer US
Gepubliceerd in
Journal of Behavioral Medicine / Uitgave 5/2021
Print ISSN: 0160-7715
Elektronisch ISSN: 1573-3521
DOI
https://doi.org/10.1007/s10865-021-00214-0

Andere artikelen Uitgave 5/2021

Journal of Behavioral Medicine 5/2021 Naar de uitgave