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23-03-2019 | ORIGINAL PAPER | Uitgave 9/2019 Open Access

Mindfulness-Based Cognitive Therapy Versus Treatment as Usual in Adults with ADHD: a Trial-Based Economic Evaluation

Tijdschrift:: Mindfulness > Uitgave 9/2019

Auteurs:: Lotte Janssen, Janneke P. C. Grutters, Melanie P. J. Schellekens, Cornelis C. Kan, Pieter J. Carpentier, Bram Sizoo, Sevket Hepark, Jan K. Buitelaar, Anne E. M. Speckens

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Abstract

Objectives

ADHD has a considerable economic impact. The aim of this study is to conduct a trial-based economic evaluation of mindfulness-based cognitive therapy (MBCT) added to treatment as usual (TAU) versus TAU in adults with ADHD.

Methods

A Dutch economic evaluation with a time horizon of 9 months was conducted from the societal perspective in the intention-to-treat (ITT) sample. Costs were assessed with a self-report questionnaire. Outcomes were expressed in quality adjusted life years (QALYs) and response rate. Bootstrap simulations were performed to estimate mean costs, QALYs, response rate, incremental cost-effectiveness ratios (ICERs), and associated uncertainty. Additional sensitivity analyses were done with imputed data, without extreme cost outliers, using the per protocol sample, and from a health care perspective.

Results

In the ITT sample, societal costs were €3572 for MBCT + TAU (n = 47; 95% CI 2416 to 4995) and €3389 for TAU (n = 49; 2327 to 4763). Average QALYs were 0.542 (0.522 to 0.563) per patient for MBCT + TAU and 0.534 (0.511 to 0.556) for TAU. In MBCT + TAU, more patients responded than in TAU (31% versus 6%; M bootstrapped difference 25%, 12 to 40%). ICERs were €21,963 per QALY gained and €389 per responder. At a threshold of €30,000 per QALY, the probability of MBCT being cost-effective was 51%. All sensitivity analyses showed more favorable results for MBCT + TAU.

Conclusions

In most analyses, MBCT was found to be more costly and effective, particularly in terms of disease-specific outcome, than TAU. If the threshold exceeds €30,000 per QALY and €1000 per responder, MBCT seemed cost-effective in treating adult ADHD.

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Meer informatie

Adler, L. A., Faraone, S. V., Spencer, T. J., Michelson, D., Reimherr, F. W., Glatt, S. J., et al. (2007). The reliability and validity of self and investigator ratings of ADHD in adults. Journal of Attention Disorders, 11(6), 711–719. CrossRef

Bachmann, K., Lam, A. P., & Philipsen, A. (2016). Mindfulness-based cognitive therapy and the adult ADHD brain: a neuropsychotherapeutic perspective. Frontiers in Psychiatry, 7(117). https://doi.org/10.3389/fpsyt.2016.00117.

Bernfort, L., Nordfeldt, S., & Persson, J. (2008). ADHD from a socio-economic perspective. Acta Paediatrica, 97(2), 239–245. CrossRef

Birnbaum, H. G., Kessler, R. C., Lowe, S. W., Secnik, K., Greenberg, P. E., Leong, S. A., et al. (2005). Costs of attention deficit–hyperactivity disorder (ADHD) in the US: excess costs of persons with ADHD and their family members in 2000. Current Medical Research and Opinion, 21(2), 195–205. CrossRef

Bogosian, A., Chadwick, P., Windgassen, S., Norton, S., McCrone, P., Mosweu, I., et al. (2015). Distress improves after mindfulness training for progressive MS: a pilot randomised trial. Multiple Sclerosis Journal, 21(9), 1184–1194. CrossRef

Bouwmans, C., & Hakkaart-van Roijen, L. (2013). TiC-P volwassenen: Vragenlijst over zorggebruik en productiviteitsverliezen bij psychische aandoeningen [TiC-P adults: Questionnaire about health consumption and productivity losses in psychiatric illness]. Rotterdam: Erasmus University.

Bouwmans, C., De Jong, K., Timman, R., Zijlstra-Vlasveld, M., Van der Feltz-Cornelis, C., Tan, S. S., et al. (2013). Feasibility, reliability and validity of a questionnaire on healthcare consumption and productivity loss in patients with a psychiatric disorder (TiC-P). BMC Health Services Research, 13(1), 217. https://doi.org/10.1186/1472-6963-13-217. CrossRefPubMedPubMedCentral

Brazier, J., Roberts, J., & Deverill, M. (2002). The estimation of a preference-based measure of health from the SF-36. Journal of Health Economics, 21(2), 271–292. CrossRef

Cairncross, M., & Miller, C. J. (2016). The effectiveness of mindfulness-based therapies for ADHD: a meta-analytic review. Journal of Attention Disorders, 1–17. https://doi.org/10.1177/1087054715625301.

Centraal Bureau voor de Statistiek (CBS) (2016). Consumentenprijzen; prijsindex 2006 = 100, 1996–2015. Retrieved from http://statline.cbs.nl/Statweb/publication/.

Crane, R. S., Kuyken, W., Williams, J. M. G., Hastings, R. P., Cooper, L., & Fennell, M. J. (2012). Competence in teaching mindfulness-based courses: concepts, development and assessment. Mindfulness, 3(1), 76–84. CrossRef

de Graaf, R., Kessler, R. C., Fayyad, J., ten Have, M., Alonso, J., Angermeyer, M., et al. (2008). The prevalence and effects of adult attention-deficit/hyperactivity disorder (ADHD) on the performance of workers: results from the WHO world mental health survey initiative. Occupational and Environmental Medicine, 65(12), 835–842. CrossRef

Doshi, J. A., Hodgkins, P., Kahle, J., Sikirica, V., Cangelosi, M. J., Setyawan, J., et al. (2012). Economic impact of childhood and adult attention-deficit/hyperactivity disorder in the United States. Journal of the American Academy of Child and Adolescent Psychiatry, 51(10), 990–1002. CrossRef

Faraone, S. V., & Glatt, S. J. (2010). A comparison of the efficacy of medications for adult attention-deficit/hyperactivity disorder using meta-analysis of effect sizes. Journal of Clinical Psychiatry, 71(6), 754–763. CrossRef

Feliu-Soler, A., Cebolla, A., McCracken, L. M., D’Amico, F., Knapp, M., López-Montoyo, A., et al. (2018). Economic impact of third-wave cognitive behavioral therapies: a systematic review and quality assessment of economic evaluations in randomized controlled trials. Behavior Therapy, 49(1), 124–147. CrossRef

First, M. B., & Gibbon, M. (2004). The structured clinical interview for DSM-IV Axis I disorders (SCID-I) and the structured clinical interview for DSM-IV Axis II disorders (SCID-II) Comprehensive handbook of psychological assessment, Vol. 2: Personality assessmen (pp. 134–143)t. Hoboken: Wiley.

Garcia, C., Bau, C., Silva, K., Callegari-Jacques, S., Salgado, C., Fischer, A., et al. (2012). The burdened life of adults with ADHD: Impairment beyond comorbidity. European Psychiatry, 27(5), 309–313. CrossRef

Hakkaart-van Roijen, L., Van der Linden, N., Bouwmans, C., Kanters, T., & Tan, S. S. (2015). Kostenhandleiding Methodologie van kostenonderzoek en referentieprijzen voor economische evaluaties in de gezondheidszorg. Geactualiseerde versie. [Dutch manual for costing in economic evaluations]. Diemen: Zorginstituut Nederland.

Hepark, S., Janssen, L., de Vries, A., Schoenberg, P. L. A., Donders, R., Kan, C. C., et al. (2015). The efficacy of adapted MBCT on core symptoms and executive functioning in adults with ADHD: a preliminary randomized controlled trial. Journal of Attention Disorders. https://doi.org/10.1177/1087054715613587.

Hinnenthal, J. A., Perwien, A. R., & Sterling, K. L. (2005). A comparison of service use and costs among adults with ADHD and adults with other chronic diseases. Psychiatric Services, 56(12), 1593–1599. CrossRef

Hodgkins, P., Montejano, L., Sasané, R., & Huse, D. (2011). Cost of illness and comorbidities in adults diagnosed with attention-deficit/hyperactivity disorder: a retrospective analysis. The Primary Care Companion CNS Disorders, 13(2). https://doi.org/10.4088/PCC.10m01030.

Househam, A. M., & Solanto, M. V. (2016). Mindfulness as an intervention for ADHD. The ADHD Report, 24(2), 1–9. CrossRef

Jacobson, N. S., & Truax, P. (1991). Clinical significance: a statistical approach to defining meaningful change in psychotherapy research. Journal of Consulting and Clinical Psychology, 59(1), 12–19. CrossRef

Janssen, L., Kan, C. C., Carpentier, P. J., Sizoo, B., Hepark, S., Grutters, J., et al. (2015). Mindfulness based cognitive therapy versus treatment as usual in adults with attention deficit hyperactivity disorder (ADHD). BMC Psychiatry, 15(1), 1–10. https://doi.org/10.1186/s12888-015-0591-x. CrossRef

Janssen, L., De Vries, A., Hepark, S., & Speckens, A. E. (2017). The feasibility, effectiveness, and process of change of mindfulness-based cognitive therapy for adults with ADHD: a mixed method pilot study. Journal of Attention Disorders. https://doi.org/10.1177/1087054717727350.

Janssen, L., Kan, C., Carpentier, P., Sizoo, B., Hepark, S., Schellekens, M., et al. (2018). Mindfulness-based cognitive therapy v. treatment as usual in adults with ADHD: a multicentre, single-blind, randomised controlled trial. Psychological Medicine, 49(1), 55–65. CrossRef

Karlsdotter, K., Bushe, C., Hakkaart, L., Sobanski, E., Kan, C., Lebrec, J., et al. (2016). Burden of illness and health care resource utilization in adult psychiatric outpatients with attention-deficit/hyperactivity disorder in Europe. Current Medical Research and Opinion, 32(9), 1547–1556. CrossRef

Kessler, R. C., Adler, L., Ames, M., Barkley, R. A., Birnbaum, H., Greenberg, P., et al. (2005). The prevalence and effects of adult attention deficit/hyperactivity disorder on work performance in a nationally representative sample of workers. Journal of Occupational and Environmental Medicine, 47(6), 565–572. CrossRef

Kessler, R., Lane, M., Stang, P., & Van Brunt, D. (2009). The prevalence and workplace costs of adult attention deficit hyperactivity disorder in a large manufacturing firm. Psychological Medicine, 39(1), 137–147. CrossRef

Kooij, J. J. S. (2010). Diagnostic interview for ADHD in adults 2.0 (DIVA 2.0) Adult ADHD: Diagnostic assessment and treatment. Amsterdam: Pearson Assessment and Information.

Kooij, J. J. S., Bejerot, S., Blackwell, A., Caci, H., Casas-Brugué, M., Carpentier, P. J., et al. (2010). European consensus statement on diagnosis and treatment of adult ADHD: the European Network Adult ADHD. BMC Psychiatry, 10(1), 67. https://doi.org/10.1186/1471-244x-10-67. CrossRefPubMedPubMedCentral

Kuyken, W., Hayes, R., Barrett, B., Byng, R., Dalgleish, T., Kessler, D., et al. (2015). Effectiveness and cost-effectiveness of mindfulness-based cognitive therapy compared with maintenance antidepressant treatment in the prevention of depressive relapse or recurrence (PREVENT): a randomised controlled trial. The Lancet, 386(9988), 63–73. CrossRef

Malinowski, P. (2013). Neural mechanisms of attentional control in mindfulness meditation. Frontiers in Neuroscience, 7(8). https://doi.org/10.3389/fnins.2013.00008.

McHorney, C. A., Ware, J. E., Jr., & Raczek, A. E. (1993). The MOS 36-item short-form health survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health constructs. Medical Care, 31(3), 247–263. CrossRef

Moriyama, T. S., Polanczyk, G. V., Terzi, F. S., Faria, K. M., & Rohde, L. A. (2013). Psychopharmacology and psychotherapy for the treatment of adults with ADHD: a systematic review of available meta-analyses. CNS Spectrums, 18(6), 296–306. CrossRef

National Institute for Health and Care Excellence (NICE). (2013). Judging whether public health interventions offer value for money. Retrieved from https://www.nice.org.uk/advice/lgb10/chapter/judging-the-cost-effectiveness-of-public-health-activities.

National Institute for Health and Care Excellence (NICE). (2018). Attention deficit hyperactivity disorder: diagnosis and management of ADHD in children, young people and adults. Leicester, UK: British Psychological Society.

Nederlandse Vereniging voor Psychiatrie (NVvP). (2015). Richtlijn ADHD bij volwassenen: Fase 1 - diagnostiek en medicamenteuze behandeling [Guidelines ADHD in adults: Phase 1 - diagnostics and pharmacotherapy]. Retrieved from https://www.nvvp.net/website/nieuws/2015/monodisciplinaire-richtlijn-adhd-bij-volwassenen-fase-1-gepubliceerd.

Rudmik, L., & Drummond, M. (2013). Health economic evaluation: important principles and methodology. Laryngoscope., 123(6), 1341–1347. CrossRef

Segal, Z. V., Williams, J. M. G., & Teasdale, J. D. (2012). Mindfulness-based cognitive therapy for depression. New York: Guilford Press.

Shah, S., Wei, H., Jayawardhana, J., Perri, M., Cobran, E., & Young, H. N. (2017). Cost–utility analysis of methylphenidate and amphetamine/dexamphetamine in adults with attention-deficit hyperactivity disorder. Journal of Pharmaceutical Health Services Research, 8(2), 101–106. CrossRef

Shawyer, F., Enticott, J. C., Özmen, M., Inder, B., & Meadows, G. N. (2016). Mindfulness-based cognitive therapy for recurrent major depression: a ‘best buy’ for health care? Australian and New Zealand Journal of Psychiatry, 50(10), 1001–1013. CrossRef

Simon, V., Czobor, P., Balint, S., Meszaros, A., & Bitter, I. (2009). Prevalence and correlates of adult attention-deficit hyperactivity disorder: meta-analysis. British Journal of Psychiatry, 194(3), 204–211. CrossRef

Van Asselt, A. D., Van Mastrigt, G. A., Dirksen, C. D., Arntz, A., Severens, J. L., & Kessels, A. G. (2009). How to deal with cost differences at baseline. Pharmacoeconomics., 27(6), 519–528. CrossRef

Van den Brink, M., Van den Hout, W. B., Stiggelbout, A. M., Van de Velde, C. J., & Kievit, J. (2004). Cost measurement in economic evaluations of health care: whom to ask? Medical Care, 42(8), 740–746. CrossRef

van Ravesteijn, H., Grutters, J., olde Hartman, T., Lucassen, P., Bor, H., van Weel, C., et al. (2013). Mindfulness-based cognitive therapy for patients with medically unexplained symptoms: a cost-effectiveness study. Journal of Psychosomatic Research, 74(3), 197–205. CrossRef

Van Vliet, I., & De Beurs, E. (2007). Het Mini Internationaal Neuropsychiatrisch Interview (MINI). Een kort gestructureerd diagnostisch psychiatrisch interview voor DSM-IV en ICD-10 stoornissen [The Mini International Neuropsychiatric Interview (MINI). A short structured diagnostic psychiatric interview for DSM-IV and ICD-10 disorders]. Tijdschrift voor Psychiatrie, 49(6), 5.

Ware, J. J., Kosinski, M., & Keller, S. D. (1996). A 12-item short-form health survey: construction of scales and preliminary tests of reliability and validity. Medical Care, 34(3), 220–233. CrossRef

Welte, R., Feenstra, T., Jager, H., & Leidl, R. (2004). A decision chart for assessing and improving the transferability of economic evaluation results between countries. Pharmacoeconomics, 22(13), 857–876. CrossRef

Zorginstituut Nederland (ZIN). (2016). Medicijnkosten. Retrieved from https://www.medicijnkosten.nl. Accessed July till September 2016.

Zorginstituut Nederland (ZIN). (2015). Kosteneffectiviteit in de praktijk [Cost-effectiveness analysis in practice]. Diemen.

Titel: Mindfulness-Based Cognitive Therapy Versus Treatment as Usual in Adults with ADHD: a Trial-Based Economic Evaluation
Auteurs:: Lotte Janssen
Janneke P. C. Grutters
Melanie P. J. Schellekens
Cornelis C. Kan
Pieter J. Carpentier
Bram Sizoo
Sevket Hepark
Jan K. Buitelaar
Anne E. M. Speckens
Publicatiedatum: 23-03-2019
DOI: https://doi.org/10.1007/s12671-019-01133-7
Uitgeverij: Springer US
Tijdschrift: Mindfulness
Uitgave 9/2019
Print ISSN: 1868-8527
Elektronisch ISSN: 1868-8535

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Publisher’s Note

Abstract

Objectives

Methods

Results

Conclusions

Onze productaanbevelingen

BSL Psychologie Totaal

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