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2015 | OriginalPaper | Hoofdstuk

Medicamenteuze preventie en behandeling van atherotrombose

Auteur : Prof. dr. F. W. A. Verheugt

Uitgeverij: Bohn Stafleu van Loghum

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Abstract

De pathofysiologie van atherotrombose is altijd terug te voeren op atherosclerose. Het natuurlijk beloop van atherosclerose is goedaardig, tenzij zich plotselinge stroomveranderingen over de stenosen voordoen. In het ergste geval raakt een vernauwd vat plotseling geheel afgesloten, waardoor het achterliggend weefsel langdurig ischemisch wordt en afsterft: het infarct. Als deze plotselinge vormen van ischemie niet kunnen worden opgevangen door collateralisatie, zal een dergelijk infarct groot zijn, met alle gevolgen van dien: pompfunctiestoornissen, maligne kamerritmestoornissen, een invaliderend of fataal herseninfarct, of een afstervend ledemaat.
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Metagegevens
Titel
Medicamenteuze preventie en behandeling van atherotrombose
Auteur
Prof. dr. F. W. A. Verheugt
Copyright
2015
Uitgeverij
Bohn Stafleu van Loghum
DOI
https://doi.org/10.1007/978-90-313-6597-5_6