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Quality of Life Research
Gepubliceerd in: Quality of Life Research 9/2012

01-11-2012

Measuring quality of life in rural Uganda: reliability and validity of summary scores from the Medical Outcomes Study HIV Health Survey (MOS-HIV)

Auteurs: Anne L. Stangl, Rebecca Bunnell, Nafuna Wamai, Humphrey Masaba, Jonathan Mermin

Gepubliceerd in: Quality of Life Research | Uitgave 9/2012

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Abstract

Purpose

Summary scores derived from the Medical Outcomes Study HIV Health Survey (MOS-HIV) are used to assess treatment impacts among HIV-infected patients in Western settings, but have yet to be validated in rural, African settings. We examined the reliability, validity and responsiveness of scores among a prospective cohort of 947 HIV-1-infected adults initiating antiretroviral therapy between May 2003 and May 2004 in rural Uganda.

Methods

Physical (PHS) and mental health (MHS) summary scores were developed from baseline MOS-HIV sub-domains using exploratory factor analysis. Construct and discriminant validity were established by comparing mean summary scores across known groups of sociodemographic, clinical and health status characteristics. Effect sizes were calculated to assess responsiveness to therapy.

Results

Reliability of the PHS and MHS scores was 0.79 and 0.85, respectively. Mean baseline PHS and MHS scores varied significantly by CD4 cell count, HIV viral load, WHO stage of disease and Karnofsky performance status scores. By 12 months on antiretroviral therapy, PHS and MHS scores improved by 14.6 points (P < 0.001) and 13.9 points (P < 0.001), respectively.

Conclusions

PHS and MHS scores can be derived from the MOS-HIV and used to assess health status among cohorts of patients taking antiretroviral therapy in rural Uganda.
vorige artikel Health of the nation outcome scales evaluation in a community setting population
volgende artikel Validation of a quality-of-life scale for women with bladder pain syndrome/interstitial cystitis
Literatuur
1.
UNAIDS, World Health Organization. (2005). Progress on global access to HIV antiretroviral therapy: An update on “3 by 5”. In Geneva, Switzerland: Joint United Nations Programme on HIV/AIDS (UNAIDS) (pp. 1–55). World Health Organization (WHO).
2.
Wu, A. W. (2000). Quality of life assessment comes of age in the era of highly active antiretroviral therapy. AIDS, 14(10), 1449–1451.PubMedCrossRef
3.
Wu, A. W., Revicki, D. A., Jacobson, D., & Malitz, F. E. (1997). Evidence for reliability, validity and usefulness of the Medical Outcomes Study HIV Health Survey (MOS-HIV). Quality of Life Research, 6(6), 481–493.PubMedCrossRef
4.
Revicki, D. A., Sorensen, S., & Wu, A. W. (1998). Reliability and validity of physical and mental health summary scores from the Medical Outcomes Study HIV Health Survey. Medical Care, 36(2), 126–137.PubMedCrossRef
5.
Holmes, W., Bix, B., & Shea, J. (1996). SF-20 score and item distributions in a human immunodeficiency virus-seropositive sample. Medical Care, 34(6), 562–569.PubMedCrossRef
6.
World Health Organization. (2002). Scaling up antiretroviral therapy in resource limited settings: Guidelines for a Public Health Approach. Geneva: World Health Organization.
7.
Bunnell, R., Ekwaru, J. P., Solberg, P., Wamai, N., Bikaako-Kajura, W., Were, W., et al. (2006). Changes in sexual behavior and risk of HIV transmission after antiretroviral therapy and prevention interventions in rural Uganda. AIDS, 20(1), 85.PubMedCrossRef
8.
Stangl, A. L., Wamai, N., Mermin, J., Awor, A. C., & Bunnell, R. (2007). Trends and predictors of quality of life among HIV-infected adults taking highly active antiretroviral therapy in rural Uganda. AIDS Care, 19(5), 626–636.PubMedCrossRef
9.
Mermin, J., Were, W., Ekwaru, J. P., Moore, D., Downing, R., Behumbiize, P., et al. (2008). Mortality in HIV-infected Ugandan adults receiving antiretroviral treatment and survival of their HIV-uninfected children: A prospective cohort study. The Lancet, 371(9614), 752–759.CrossRef
10.
Mast, T. C., Kigozi, G., Wabwire-Mangen, F., Black, R., Sewankambo, N., Serwadda, D., et al. (2004). Measuring quality of life among HIV-infected women using a culturally adapted questionnaire in Rakai district, Uganda. AIDS Care, 16(1), 81–94.PubMedCrossRef
11.
WHO, & The WHO International Collaborating Group for the study of the WHO staging system. (1993). Proposed ‘World Health Organization staging system for HIV infection and disease’: preliminary testing by an international collaborative cross-sectional study. The WHO International Collaborating Group for the Study of the WHO Staging System. AIDS, 7(5), 711–718.
12.
Mor, V., Laliberte, L., Morris, J. N., & Wiemann, M. (1984). The Karnofsky performance status scale: An examination of its reliability and validity in a research setting. Cancer, 53(9), 2002–2007.PubMedCrossRef
13.
Kazis, L. E., Anderson, J. J., & Meenan, R. F. (1989). Effect sizes for interpreting changes in health status. Medical Care, 27(3), S178.PubMedCrossRef
14.
Hedges, L. V., & Olkin, I. (1985). Statistical methods for meta-analysis. New York: Academic Press.
15.
Cohen, J. (1988). Statistical power analysis for the behavioral sciences. Hillsdale: Lawrence Erlbaum Associates.
16.
Katz, J. N., Larson, M. G., Phillips, C. B., Fossel, A. H., & Liang, M. H. (1992). Comparative measurement sensitivity of short and longer health status instruments. Medical Care, 30(10), 917–925.PubMedCrossRef
17.
Bolton, P., & Tang, A. M. (2002). An alternative approach to cross-cultural function assessment. Social Psychiatry and Psychiatric Epidemiology, 37(11), 537–543.PubMedCrossRef
18.
Murri, R., Fantoni, M., Del Borgo, C., Visona, R., Barracco, A., Zambelli, A., et al. (2003). Determinants of health-related quality of life in HIV-infected patients. AIDS Care, 15(4), 581–590.PubMedCrossRef
19.
Liu, C., Johnson, L., Ostrow, D., Silvestre, A., Visscher, B., & Jacobson, L. P. (2006). Predictors for lower quality of life in the HAART era among HIV-infected men. Journal of Acquired Immune Deficiency Syndromes, 42(4), 470.PubMedCrossRef
20.
Mannheimer, S. B., Matts, J., Telzak, E., Chesney, M., Child, C., Wu, A. W., et al. (2005). Quality of life in HIV-infected individuals receiving antiretroviral therapy is related to adherence. AIDS Care, 17(1), 10–22.PubMedCrossRef
21.
Cederfjall, C., Langius-Eklof, A., Lidman, K., & Wredling, R. (2001). Gender differences in perceived health-related quality of life among patients with HIV infection. AIDS Patient Care STDs, 15(1), 31–39.PubMedCrossRef
22.
Babikako, H. M., Neuhauser, D., Katamba, A., & Mupere, E. (2010). Feasibility, reliability and validity of health-related quality of life questionnaire among adult pulmonary tuberculosis patients in urban Uganda: Cross-sectional study. Health and Quality of Life Outcomes, 8, 93.PubMedCrossRef
23.
Bajunirwe, F., Tisch, D. J., King, C. H., Arts, E. J., Debanne, S. M., & Sethi, A. K. (2009). Quality of life and social support among patients receiving antiretroviral therapy in Western Uganda. AIDS Care, 21(3), 271–279.PubMedCrossRef
24.
Sowell, R. L., Seals, B. F., Moneyham, L., Demi, A., Cohen, L., & Brake, S. (1997). Quality of life in HIV-infected women in the south-eastern United States. AIDS Care, 9(5), 501–512.PubMedCrossRef
25.
Cohen, C., Revicki, D. A., Nabulsi, A., Sarocco, P. W., & Jiang, P. (1998). A randomized trial of the effect of ritonavir in maintaining quality of life in advanced HIV disease. AIDS, 12(12), 1495.PubMedCrossRef
26.
Tarwater, P. M., Gallant, J. E., Mellors, J. W., Gore, M. E., Phair, J. P., Detels, R., et al. (2004). Prognostic value of plasma HIV RNA among highly active antiretroviral therapy users. AIDS, 18(18), 2419.PubMed
27.
Wu, A. W., Rubin, H. R., Mathews, W. C., Ware, J. E., Jr, Brysk, L. T., Hardy, W. D., et al. (1991). A health status questionnaire using 30 items from the Medical Outcomes Study: Preliminary validation in persons with early HIV infection. Medical Care, 29(8), 786.PubMedCrossRef
Metagegevens
Titel
Measuring quality of life in rural Uganda: reliability and validity of summary scores from the Medical Outcomes Study HIV Health Survey (MOS-HIV)
Auteurs
Anne L. Stangl
Rebecca Bunnell
Nafuna Wamai
Humphrey Masaba
Jonathan Mermin
Publicatiedatum
01-11-2012
Uitgeverij
Springer Netherlands
Gepubliceerd in
Quality of Life Research / Uitgave 9/2012
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-011-0075-5

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