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Journal of Autism and Developmental Disorders

Gepubliceerd in:

24-12-2013 | Original Paper

Maternal Infection During Pregnancy and Autism Spectrum Disorders

Auteurs: Ousseny Zerbo, Yinge Qian, Cathleen Yoshida, Judith K. Grether, Judy Van de Water, Lisa A. Croen

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 12/2015

Abstract

We conducted a nested case–control study including 407 cases and 2,075 frequency matched controls to investigate the association between maternal infections during pregnancy and risk of autism spectrum disorders (ASD). Cases, controls, and maternal infections were ascertained from Kaiser Permanente Northern California clinical databases. No overall association between diagnoses of any maternal infection during pregnancy and ASD was observed [adjusted odds ratio (OR_adj) = 1.15, 95 % confidence interval (CI) 0.92–1.43]. However, women with infections diagnosed during a hospital admission (OR_adj = 1.48, 95 % CI 1.07–2.04), particularly bacterial infections (OR_adj = 1.58, 95 % CI 1.06–2.37), were at increased risk of delivering a child with ASD. Multiple infections during pregnancy were associated with ASD (OR_adj = 1.36, 95 % CI 1.05–1.78).

vorige artikel A Study of Physician Knowledge and Experience with Autism in Adults in a Large Integrated Healthcare System

volgende artikel Personality Pathology of Adults With Autism Spectrum Disorder Without Accompanying Intellectual Impairment in Comparison to Adults With Personality Disorders

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Titel: Maternal Infection During Pregnancy and Autism Spectrum Disorders
Auteurs: Ousseny Zerbo
Yinge Qian
Cathleen Yoshida
Judith K. Grether
Judy Van de Water
Lisa A. Croen
Publicatiedatum: 24-12-2013
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 12/2015
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-013-2016-3

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