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12-05-2021 | Original Paper

Maternal Exposure to Pesticides and Risk of Autism Spectrum Disorders in Offspring: A Meta-analysis

Auteurs: Li Wang, Shiming Tang, Songjie Wu, Lihua Yao, Dezhen Su, Ying Wang

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 4/2022

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Abstract

This meta-analysis was conducted to estimate the overall association between maternal exposure to pesticides and risk of ASD in offspring. PubMed, EMBASE, Web of Science, and the PsycINFO were searched until December 30, 2020 to include eligible studies. Eight studies with 50,426 participants, 5810 of whom had ASD, were involved in the study. Overall, the summary OR (95% confidence interval) of ASDs in offspring for maternal exposure to pesticide estimated by residential proximity measures and self-report was 1.88 (1.10–3.20). However, maternal exposure to pesticide measured by biomarkers was not associated with an increased risk of ASDs (pooled OR 1.13; 95% CI 0.83–1.54). Further well-designed studies are needed to confirm our findings.
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Metagegevens
Titel
Maternal Exposure to Pesticides and Risk of Autism Spectrum Disorders in Offspring: A Meta-analysis
Auteurs
Li Wang
Shiming Tang
Songjie Wu
Lihua Yao
Dezhen Su
Ying Wang
Publicatiedatum
12-05-2021
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 4/2022
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-021-05063-z