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Gepubliceerd in: Journal of Autism and Developmental Disorders 4/2014

01-04-2014 | Original Paper

Maternal Diabetes and the Risk of Autism Spectrum Disorders in the Offspring: A Systematic Review and Meta-Analysis

Auteurs: Guifeng Xu, Jin Jing, Katherine Bowers, Buyun Liu, Wei Bao

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 4/2014

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Abstract

We performed a systematic literature search regarding maternal diabetes before and during pregnancy and the risk of autism spectrum disorders (ASD) in the offspring. Of the 178 potentially relevant articles, 12 articles including three cohort studies and nine case–control studies were included in the meta-analysis. Both the meta-analyses of cohort studies and case–control studies showed significant associations. The pooled relative risk and 95 % confidence interval (CI) among cohort studies was 1.48 (1.25–1.75, p < 0.001). For case–control studies, the pooled odds ratio and 95 % CI was 1.72 (1.24–2.41, p = 0.001). No indication of significant heterogeneity across studies or publication bias was observed. In conclusion, maternal diabetes was significantly associated with a greater risk of ASD in the offspring.
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Literatuur
go back to reference Albrecht, S. S., Kuklina, E. V., Bansil, P., Jamieson, D. J., Whiteman, M. K., Kourtis, A. P., et al. (2010). Diabetes trends among delivery hospitalizations in the US, 1994–2004. Diabetes Care, 33, 768–773. PubMedCentralPubMedCrossRef Albrecht, S. S., Kuklina, E. V., Bansil, P., Jamieson, D. J., Whiteman, M. K., Kourtis, A. P., et al. (2010). Diabetes trends among delivery hospitalizations in the US, 1994–2004. Diabetes Care, 33, 768–773. PubMedCentralPubMedCrossRef
go back to reference American Diabetes Association. (2004). Gestational diabetes mellitus. Diabetes Care, 27(Suppl 1), S88–S90. American Diabetes Association. (2004). Gestational diabetes mellitus. Diabetes Care, 27(Suppl 1), S88–S90.
go back to reference American Diabetes Association. (2013). Diagnosis and classification of diabetes mellitus. Diabetes Care, 36(Suppl 1), S67–S74. PubMedCentralCrossRef American Diabetes Association. (2013). Diagnosis and classification of diabetes mellitus. Diabetes Care, 36(Suppl 1), S67–S74. PubMedCentralCrossRef
go back to reference Anderson, J. L., Waller, D. K., Canfield, M. A., Shaw, G. M., Watkins, M. L., & Werler, M. M. (2005). Maternal obesity, gestational diabetes, and central nervous system birth defects. Epidemiology, 16, 87–92. PubMedCrossRef Anderson, J. L., Waller, D. K., Canfield, M. A., Shaw, G. M., Watkins, M. L., & Werler, M. M. (2005). Maternal obesity, gestational diabetes, and central nervous system birth defects. Epidemiology, 16, 87–92. PubMedCrossRef
go back to reference Autism and Developmental Disabilities Monitoring Network Surveillance Year 2008 Principal Investigators; Centers for Disease Control and Prevention. (2012). Prevalence of autism spectrum disorders–Autism and Developmental Disabilities Monitoring Network, 14 sites, United States, 2008. MMWR Surveill Summ, 61, 1–19. Autism and Developmental Disabilities Monitoring Network Surveillance Year 2008 Principal Investigators; Centers for Disease Control and Prevention. (2012). Prevalence of autism spectrum disorders–Autism and Developmental Disabilities Monitoring Network, 14 sites, United States, 2008. MMWR Surveill Summ, 61, 1–19.
go back to reference Bailey, A., Le Couteur, A., Gottesman, I., Bolton, P., Simonoff, E., Yuzda, E., et al. (1995). Autism as a strongly genetic disorder: evidence from a British twin study. Psychological Medicine, 25, 63–77. PubMedCrossRef Bailey, A., Le Couteur, A., Gottesman, I., Bolton, P., Simonoff, E., Yuzda, E., et al. (1995). Autism as a strongly genetic disorder: evidence from a British twin study. Psychological Medicine, 25, 63–77. PubMedCrossRef
go back to reference Bardenheier, B. H., Elixhauser, A., Imperatore, G., Devlin, H. M., Kuklina, E. V., Geiss, L. S., et al. (2013). Variation in prevalence of gestational diabetes mellitus among hospital discharges for obstetric delivery across 23 states in the United States. Diabetes Care, 36, 1209–1214. PubMedCrossRef Bardenheier, B. H., Elixhauser, A., Imperatore, G., Devlin, H. M., Kuklina, E. V., Geiss, L. S., et al. (2013). Variation in prevalence of gestational diabetes mellitus among hospital discharges for obstetric delivery across 23 states in the United States. Diabetes Care, 36, 1209–1214. PubMedCrossRef
go back to reference Bell, R., Bailey, K., Cresswell, T., Hawthorne, G., Critchley, J., & Lewis-Barned, N. (2008). Trends in prevalence and outcomes of pregnancy in women with pre-existing type I and type II diabetes. BJOG: An International Journal of Obstetrics and Gynaecology, 115, 445–452. CrossRef Bell, R., Bailey, K., Cresswell, T., Hawthorne, G., Critchley, J., & Lewis-Barned, N. (2008). Trends in prevalence and outcomes of pregnancy in women with pre-existing type I and type II diabetes. BJOG: An International Journal of Obstetrics and Gynaecology, 115, 445–452. CrossRef
go back to reference Biri, A., Onan, A., Devrim, E., Babacan, F., Kavutcu, M., & Durak, I. (2006). Oxidant status in maternal and cord plasma and placental tissue in gestational diabetes. Placenta, 27, 327–332. PubMedCrossRef Biri, A., Onan, A., Devrim, E., Babacan, F., Kavutcu, M., & Durak, I. (2006). Oxidant status in maternal and cord plasma and placental tissue in gestational diabetes. Placenta, 27, 327–332. PubMedCrossRef
go back to reference Brimacombe, M., Ming, X., & Lamendola, M. (2007). Prenatal and birth complications in autism. Maternal and Child Health Journal, 11, 73–79. PubMedCrossRef Brimacombe, M., Ming, X., & Lamendola, M. (2007). Prenatal and birth complications in autism. Maternal and Child Health Journal, 11, 73–79. PubMedCrossRef
go back to reference Buchmayer, S., Johansson, S., Johansson, A., Hultman, C. M., Sparen, P., & Cnattingius, S. (2009). Can association between preterm birth and autism be explained by maternal or neonatal morbidity? Pediatrics, 124, e817–e825. PubMedCrossRef Buchmayer, S., Johansson, S., Johansson, A., Hultman, C. M., Sparen, P., & Cnattingius, S. (2009). Can association between preterm birth and autism be explained by maternal or neonatal morbidity? Pediatrics, 124, e817–e825. PubMedCrossRef
go back to reference Burstyn, I., Sithole, F., & Zwaigenbaum, L. (2010). Autism spectrum disorders, maternal characteristics and obstetric complications among singletons born in Alberta, Canada. Chronic Diseases in Canada, 30, 125–134. PubMed Burstyn, I., Sithole, F., & Zwaigenbaum, L. (2010). Autism spectrum disorders, maternal characteristics and obstetric complications among singletons born in Alberta, Canada. Chronic Diseases in Canada, 30, 125–134. PubMed
go back to reference Burstyn, I., Wang, X., Yasui, Y., Sithole, F., & Zwaigenbaum, L. (2011). Autism spectrum disorders and fetal hypoxia in a population-based cohort: accounting for missing exposures via Estimation-Maximization algorithm. BMC Medical Research Methodology, 11, 2. PubMedCentralPubMedCrossRef Burstyn, I., Wang, X., Yasui, Y., Sithole, F., & Zwaigenbaum, L. (2011). Autism spectrum disorders and fetal hypoxia in a population-based cohort: accounting for missing exposures via Estimation-Maximization algorithm. BMC Medical Research Methodology, 11, 2. PubMedCentralPubMedCrossRef
go back to reference Chauhan, A., Chauhan, V., Brown, W. T., & Cohen, I. (2004). Oxidative stress in autism: increased lipid peroxidation and reduced serum levels of ceruloplasmin and transferrin–the antioxidant proteins. Life Sciences, 75, 2539–2549. PubMedCrossRef Chauhan, A., Chauhan, V., Brown, W. T., & Cohen, I. (2004). Oxidative stress in autism: increased lipid peroxidation and reduced serum levels of ceruloplasmin and transferrin–the antioxidant proteins. Life Sciences, 75, 2539–2549. PubMedCrossRef
go back to reference Chen, X., & Scholl, T. O. (2005). Oxidative stress: Changes in pregnancy and with gestational diabetes mellitus. Current Diabetes Reports, 5, 282–288. PubMedCrossRef Chen, X., & Scholl, T. O. (2005). Oxidative stress: Changes in pregnancy and with gestational diabetes mellitus. Current Diabetes Reports, 5, 282–288. PubMedCrossRef
go back to reference Croen, L. A., Grether, J. K., Yoshida, C. K., Odouli, R., & Van de Water, J. (2005). Maternal autoimmune diseases, asthma and allergies, and childhood autism spectrum disorders: A case-control study. Archives of Pediatrics and Adolescent Medicine, 159, 151–157. PubMedCrossRef Croen, L. A., Grether, J. K., Yoshida, C. K., Odouli, R., & Van de Water, J. (2005). Maternal autoimmune diseases, asthma and allergies, and childhood autism spectrum disorders: A case-control study. Archives of Pediatrics and Adolescent Medicine, 159, 151–157. PubMedCrossRef
go back to reference DerSimonian, R., & Laird, N. (1986). Meta-analysis in clinical trials. Controlled Clinical Trials, 7, 177–188. PubMedCrossRef DerSimonian, R., & Laird, N. (1986). Meta-analysis in clinical trials. Controlled Clinical Trials, 7, 177–188. PubMedCrossRef
go back to reference Dodds, L., Fell, D. B., Shea, S., Armson, B. A., Allen, A. C., & Bryson, S. (2011). The role of prenatal, obstetric and neonatal factors in the development of autism. Journal of Autism and Developmental Disorders, 41, 891–902. PubMedCrossRef Dodds, L., Fell, D. B., Shea, S., Armson, B. A., Allen, A. C., & Bryson, S. (2011). The role of prenatal, obstetric and neonatal factors in the development of autism. Journal of Autism and Developmental Disorders, 41, 891–902. PubMedCrossRef
go back to reference Eidelman, A. I., & Samueloff, A. (2002). The pathophysiology of the fetus of the diabetic mother. Seminars in Perinatology, 26, 232–236. PubMedCrossRef Eidelman, A. I., & Samueloff, A. (2002). The pathophysiology of the fetus of the diabetic mother. Seminars in Perinatology, 26, 232–236. PubMedCrossRef
go back to reference Elhameed, M. A. A., Elbaky, A. E. O. A., & Kamel, E. A. (2011). A controlled study of the risk factors and clinical picture of children with autism in an Egyptian sample. Egypt Journal of Neurology, Neurosurgery and Psychiatry, 48, 271–276. Elhameed, M. A. A., Elbaky, A. E. O. A., & Kamel, E. A. (2011). A controlled study of the risk factors and clinical picture of children with autism in an Egyptian sample. Egypt Journal of Neurology, Neurosurgery and Psychiatry, 48, 271–276.
go back to reference Fernandez-Morera, J. L., Rodriguez-Rodero, S., Menendez-Torre, E., & Fraga, M. F. (2010). The possible role of epigenetics in gestational diabetes: Cause, consequence, or both. Obstetrics and Gynecology International, 2010, 605163. PubMedCentralPubMedCrossRef Fernandez-Morera, J. L., Rodriguez-Rodero, S., Menendez-Torre, E., & Fraga, M. F. (2010). The possible role of epigenetics in gestational diabetes: Cause, consequence, or both. Obstetrics and Gynecology International, 2010, 605163. PubMedCentralPubMedCrossRef
go back to reference Ferrara, A. (2007). Increasing prevalence of gestational diabetes mellitus: A public health perspective. Diabetes Care, 30(Suppl 2), S141–S146. PubMedCrossRef Ferrara, A. (2007). Increasing prevalence of gestational diabetes mellitus: A public health perspective. Diabetes Care, 30(Suppl 2), S141–S146. PubMedCrossRef
go back to reference Gardener, H., Spiegelman, D., & Buka, S. L. (2009). Prenatal risk factors for autism: Comprehensive meta-analysis. British Journal of Psychiatry, 195, 7–14. PubMedCentralPubMedCrossRef Gardener, H., Spiegelman, D., & Buka, S. L. (2009). Prenatal risk factors for autism: Comprehensive meta-analysis. British Journal of Psychiatry, 195, 7–14. PubMedCentralPubMedCrossRef
go back to reference Gardener, H., Spiegelman, D., & Buka, S. L. (2011). Perinatal and neonatal risk factors for autism: A comprehensive meta-analysis. Pediatrics, 128, 344–355. PubMedCentralPubMedCrossRef Gardener, H., Spiegelman, D., & Buka, S. L. (2011). Perinatal and neonatal risk factors for autism: A comprehensive meta-analysis. Pediatrics, 128, 344–355. PubMedCentralPubMedCrossRef
go back to reference Georgieff, M. K. (2006). The effect of maternal diabetes during pregnancy on the neurodevelopment of offspring. Minnesota Medicine, 89, 44–47. PubMed Georgieff, M. K. (2006). The effect of maternal diabetes during pregnancy on the neurodevelopment of offspring. Minnesota Medicine, 89, 44–47. PubMed
go back to reference Gillberg, C. (1999). Neurodevelopmental processes and psychological functioning in autism. Development and Psychopathology, 11, 567–587. PubMedCrossRef Gillberg, C. (1999). Neurodevelopmental processes and psychological functioning in autism. Development and Psychopathology, 11, 567–587. PubMedCrossRef
go back to reference Guinchat, V., Thorsen, P., Laurent, C., Cans, C., Bodeau, N., & Cohen, D. (2012). Pre-, peri- and neonatal risk factors for autism. Acta Obstetricia et Gynecologica Scandinavica, 91, 287–300. PubMedCrossRef Guinchat, V., Thorsen, P., Laurent, C., Cans, C., Bodeau, N., & Cohen, D. (2012). Pre-, peri- and neonatal risk factors for autism. Acta Obstetricia et Gynecologica Scandinavica, 91, 287–300. PubMedCrossRef
go back to reference Hayes, D. K., Fan, A. Z., Smith, R. A., & Bombard, J. M. (2011). Trends in selected chronic conditions and behavioral risk factors among women of reproductive age, behavioral risk factor surveillance system, 2001–2009. Preventing Chronic Disease, 8, A120. PubMedCentralPubMed Hayes, D. K., Fan, A. Z., Smith, R. A., & Bombard, J. M. (2011). Trends in selected chronic conditions and behavioral risk factors among women of reproductive age, behavioral risk factor surveillance system, 2001–2009. Preventing Chronic Disease, 8, A120. PubMedCentralPubMed
go back to reference Herrera, E., & Ortega-Senovilla, H. (2010). Disturbances in lipid metabolism in diabetic pregnancy: Are these the cause of the problem? Best Practice and Research Clinical Endocrinology and Metabolism, 24, 515–525. PubMedCrossRef Herrera, E., & Ortega-Senovilla, H. (2010). Disturbances in lipid metabolism in diabetic pregnancy: Are these the cause of the problem? Best Practice and Research Clinical Endocrinology and Metabolism, 24, 515–525. PubMedCrossRef
go back to reference Higgins, J. P., & Thompson, S. G. (2002). Quantifying heterogeneity in a meta-analysis. Statistics in Medicine, 21, 1539–1558. PubMedCrossRef Higgins, J. P., & Thompson, S. G. (2002). Quantifying heterogeneity in a meta-analysis. Statistics in Medicine, 21, 1539–1558. PubMedCrossRef
go back to reference Huerta, J. M., Tormo, M. J., Egea-Caparros, J. M., Ortola-Devesa, J. B., & Navarro, C. (2009). Accuracy of self-reported diabetes, hypertension and hyperlipidemia in the adult Spanish population. DINO study findings. Revista Espanola de Cardiologia, 62, 143–152. PubMedCrossRef Huerta, J. M., Tormo, M. J., Egea-Caparros, J. M., Ortola-Devesa, J. B., & Navarro, C. (2009). Accuracy of self-reported diabetes, hypertension and hyperlipidemia in the adult Spanish population. DINO study findings. Revista Espanola de Cardiologia, 62, 143–152. PubMedCrossRef
go back to reference Hultman, C. M., Sparen, P., & Cnattingius, S. (2002). Perinatal risk factors for infantile autism. Epidemiology, 13, 417–423. PubMedCrossRef Hultman, C. M., Sparen, P., & Cnattingius, S. (2002). Perinatal risk factors for infantile autism. Epidemiology, 13, 417–423. PubMedCrossRef
go back to reference Juul-Dam, N., Townsend, J., & Courchesne, E. (2001). Prenatal, perinatal, and neonatal factors in autism, pervasive developmental disorder-not otherwise specified, and the general population. Pediatrics, 107, E63. PubMedCrossRef Juul-Dam, N., Townsend, J., & Courchesne, E. (2001). Prenatal, perinatal, and neonatal factors in autism, pervasive developmental disorder-not otherwise specified, and the general population. Pediatrics, 107, E63. PubMedCrossRef
go back to reference Keil, A., Daniels, J. L., Forssen, U., Hultman, C., Cnattingius, S., Soderberg, K. C., et al. (2010). Parental autoimmune diseases associated with autism spectrum disorders in offspring. Epidemiology, 21, 805–808. PubMedCentralPubMedCrossRef Keil, A., Daniels, J. L., Forssen, U., Hultman, C., Cnattingius, S., Soderberg, K. C., et al. (2010). Parental autoimmune diseases associated with autism spectrum disorders in offspring. Epidemiology, 21, 805–808. PubMedCentralPubMedCrossRef
go back to reference Kolevzon, A., Gross, R., & Reichenberg, A. (2007). Prenatal and perinatal risk factors for autism: a review and integration of findings. Archives of Pediatrics and Adolescent Medicine, 161, 326–333. PubMedCrossRef Kolevzon, A., Gross, R., & Reichenberg, A. (2007). Prenatal and perinatal risk factors for autism: a review and integration of findings. Archives of Pediatrics and Adolescent Medicine, 161, 326–333. PubMedCrossRef
go back to reference Krakowiak, P., Walker, C. K., Bremer, A. A., Baker, A. S., Ozonoff, S., Hansen, R. L., et al. (2012). Maternal metabolic conditions and risk for autism and other neurodevelopmental disorders. Pediatrics, 129, e1121–e1128. PubMedCentralPubMedCrossRef Krakowiak, P., Walker, C. K., Bremer, A. A., Baker, A. S., Ozonoff, S., Hansen, R. L., et al. (2012). Maternal metabolic conditions and risk for autism and other neurodevelopmental disorders. Pediatrics, 129, e1121–e1128. PubMedCentralPubMedCrossRef
go back to reference Leonard, H., de Klerk, N., Bourke, J., & Bower, C. (2006). Maternal health in pregnancy and intellectual disability in the offspring: A population-based study. Annals of Epidemiology, 16, 448–454. PubMedCrossRef Leonard, H., de Klerk, N., Bourke, J., & Bower, C. (2006). Maternal health in pregnancy and intellectual disability in the offspring: A population-based study. Annals of Epidemiology, 16, 448–454. PubMedCrossRef
go back to reference Levy, S. E., Mandell, D. S., & Schultz, R. T. (2009). Autism. Lancet, 374, 1627–1638. CrossRef Levy, S. E., Mandell, D. S., & Schultz, R. T. (2009). Autism. Lancet, 374, 1627–1638. CrossRef
go back to reference London, E. A. (2000). The environment as an etiologic factor in autism: A new direction for research. Environmental Health Perspectives, 108(Suppl 3), 401–404. PubMedCentralPubMed London, E. A. (2000). The environment as an etiologic factor in autism: A new direction for research. Environmental Health Perspectives, 108(Suppl 3), 401–404. PubMedCentralPubMed
go back to reference Lyall, K., Pauls, D. L., Spiegelman, D., Ascherio, A., & Santangelo, S. L. (2012). Pregnancy complications and obstetric suboptimality in association with autism spectrum disorders in children of the Nurses’ Health Study II. Autism Research, 5, 21–30. PubMedCentralPubMedCrossRef Lyall, K., Pauls, D. L., Spiegelman, D., Ascherio, A., & Santangelo, S. L. (2012). Pregnancy complications and obstetric suboptimality in association with autism spectrum disorders in children of the Nurses’ Health Study II. Autism Research, 5, 21–30. PubMedCentralPubMedCrossRef
go back to reference Ming, X., Stein, T. P., Brimacombe, M., Johnson, W. G., Lambert, G. H., & Wagner, G. C. (2005). Increased excretion of a lipid peroxidation biomarker in autism. Prostaglandins Leukotrienes and Essential Fatty Acids, 73, 379–384. CrossRef Ming, X., Stein, T. P., Brimacombe, M., Johnson, W. G., Lambert, G. H., & Wagner, G. C. (2005). Increased excretion of a lipid peroxidation biomarker in autism. Prostaglandins Leukotrienes and Essential Fatty Acids, 73, 379–384. CrossRef
go back to reference National Institute for Health and Care Excellence. (2009). NICE clinical guidelines 63: Diabetes in pregnancy: Management of diabetes and its complications from pre-conception to the postnatal period. Accessed July 10, 2013, from http://​guidance.​nice.​org.​uk/​CG63. National Institute for Health and Care Excellence. (2009). NICE clinical guidelines 63: Diabetes in pregnancy: Management of diabetes and its complications from pre-conception to the postnatal period. Accessed July 10, 2013, from http://​guidance.​nice.​org.​uk/​CG63.
go back to reference Newschaffer, C. J., Croen, L. A., Daniels, J., Giarelli, E., Grether, J. K., Levy, S. E., et al. (2007). The epidemiology of autism spectrum disorders. Annual Review of Public Health, 28, 235–258. PubMedCrossRef Newschaffer, C. J., Croen, L. A., Daniels, J., Giarelli, E., Grether, J. K., Levy, S. E., et al. (2007). The epidemiology of autism spectrum disorders. Annual Review of Public Health, 28, 235–258. PubMedCrossRef
go back to reference Okura, Y., Urban, L. H., Mahoney, D. W., Jacobsen, S. J., & Rodeheffer, R. J. (2004). Agreement between self-report questionnaires and medical record data was substantial for diabetes, hypertension, myocardial infarction and stroke but not for heart failure. Journal of Clinical Epidemiology, 57, 1096–1103. PubMedCrossRef Okura, Y., Urban, L. H., Mahoney, D. W., Jacobsen, S. J., & Rodeheffer, R. J. (2004). Agreement between self-report questionnaires and medical record data was substantial for diabetes, hypertension, myocardial infarction and stroke but not for heart failure. Journal of Clinical Epidemiology, 57, 1096–1103. PubMedCrossRef
go back to reference Onore, C., Careaga, M., & Ashwood, P. (2012). The role of immune dysfunction in the pathophysiology of autism. Brain, Behavior, and Immunity, 26, 383–392. PubMedCentralPubMedCrossRef Onore, C., Careaga, M., & Ashwood, P. (2012). The role of immune dysfunction in the pathophysiology of autism. Brain, Behavior, and Immunity, 26, 383–392. PubMedCentralPubMedCrossRef
go back to reference Ornoy, A., Ratzon, N., Greenbaum, C., Wolf, A., & Dulitzky, M. (2001). School-age children born to diabetic mothers and to mothers with gestational diabetes exhibit a high rate of inattention and fine and gross motor impairment. Journal of Pediatric Endocrinology and Metabolism, 14(Suppl 1), 681–689. PubMed Ornoy, A., Ratzon, N., Greenbaum, C., Wolf, A., & Dulitzky, M. (2001). School-age children born to diabetic mothers and to mothers with gestational diabetes exhibit a high rate of inattention and fine and gross motor impairment. Journal of Pediatric Endocrinology and Metabolism, 14(Suppl 1), 681–689. PubMed
go back to reference Piven, J., Simon, J., Chase, G. A., Wzorek, M., Landa, R., Gayle, J., et al. (1993). The etiology of autism: Pre-, peri- and neonatal factors. Journal of the American Academy of Child and Adolescent Psychiatry, 32, 1256–1263. PubMedCrossRef Piven, J., Simon, J., Chase, G. A., Wzorek, M., Landa, R., Gayle, J., et al. (1993). The etiology of autism: Pre-, peri- and neonatal factors. Journal of the American Academy of Child and Adolescent Psychiatry, 32, 1256–1263. PubMedCrossRef
go back to reference Rapin, I. (2002). The autistic-spectrum disorders. New England Journal of Medicine, 347, 302–303. PubMedCrossRef Rapin, I. (2002). The autistic-spectrum disorders. New England Journal of Medicine, 347, 302–303. PubMedCrossRef
go back to reference Rizzo, T. A., Dooley, S. L., Metzger, B. E., Cho, N. H., Ogata, E. S., & Silverman, B. L. (1995). Prenatal and perinatal influences on long-term psychomotor development in offspring of diabetic mothers. American Journal of Obstetrics and Gynecology, 173, 1753–1758. PubMedCrossRef Rizzo, T. A., Dooley, S. L., Metzger, B. E., Cho, N. H., Ogata, E. S., & Silverman, B. L. (1995). Prenatal and perinatal influences on long-term psychomotor development in offspring of diabetic mothers. American Journal of Obstetrics and Gynecology, 173, 1753–1758. PubMedCrossRef
go back to reference Rodier, P. M., Ingram, J. L., Tisdale, B., Nelson, S., & Romano, J. (1996). Embryological origin for autism: developmental anomalies of the cranial nerve motor nuclei. Journal of Comparative Neurology, 370, 247–261. PubMedCrossRef Rodier, P. M., Ingram, J. L., Tisdale, B., Nelson, S., & Romano, J. (1996). Embryological origin for autism: developmental anomalies of the cranial nerve motor nuclei. Journal of Comparative Neurology, 370, 247–261. PubMedCrossRef
go back to reference Schanen, N. C. (2006). Epigenetics of autism spectrum disorders. Hum Mol Genet, 15(2), R138–R150. PubMedCrossRef Schanen, N. C. (2006). Epigenetics of autism spectrum disorders. Hum Mol Genet, 15(2), R138–R150. PubMedCrossRef
go back to reference Solomon, C. G., Willett, W. C., Carey, V. J., Rich-Edwards, J., Hunter, D. J., Colditz, G. A., et al. (1997). A prospective study of pregravid determinants of gestational diabetes mellitus. The Journal of the American Medical Association, 278, 1078–1083. CrossRef Solomon, C. G., Willett, W. C., Carey, V. J., Rich-Edwards, J., Hunter, D. J., Colditz, G. A., et al. (1997). A prospective study of pregravid determinants of gestational diabetes mellitus. The Journal of the American Medical Association, 278, 1078–1083. CrossRef
go back to reference Stroup, D. F., Berlin, J. A., Morton, S. C., Olkin, I., Williamson, G. D., Rennie, D., et al. (2000). Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. The Journal of the American Medical Association, 283, 2008–2012. CrossRef Stroup, D. F., Berlin, J. A., Morton, S. C., Olkin, I., Williamson, G. D., Rennie, D., et al. (2000). Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. The Journal of the American Medical Association, 283, 2008–2012. CrossRef
go back to reference Van den Bergh, B. R. (2011). Developmental programming of early brain and behaviour development and mental health: a conceptual framework. Developmental Medicine and Child Neurology, 53(Suppl 4), 19–23. PubMedCrossRef Van den Bergh, B. R. (2011). Developmental programming of early brain and behaviour development and mental health: a conceptual framework. Developmental Medicine and Child Neurology, 53(Suppl 4), 19–23. PubMedCrossRef
go back to reference Wong, V. C., & Hui, S. L. (2008). Epidemiological study of autism spectrum disorder in China. Journal of Child Neurology, 23, 67–72. PubMedCrossRef Wong, V. C., & Hui, S. L. (2008). Epidemiological study of autism spectrum disorder in China. Journal of Child Neurology, 23, 67–72. PubMedCrossRef
go back to reference Yao, Y., Walsh, W. J., McGinnis, W. R., & Pratico, D. (2006). Altered vascular phenotype in autism: correlation with oxidative stress. Archives of Neurology, 63, 1161–1164. PubMedCrossRef Yao, Y., Walsh, W. J., McGinnis, W. R., & Pratico, D. (2006). Altered vascular phenotype in autism: correlation with oxidative stress. Archives of Neurology, 63, 1161–1164. PubMedCrossRef
Metagegevens
Titel
Maternal Diabetes and the Risk of Autism Spectrum Disorders in the Offspring: A Systematic Review and Meta-Analysis
Auteurs
Guifeng Xu
Jin Jing
Katherine Bowers
Buyun Liu
Wei Bao
Publicatiedatum
01-04-2014
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 4/2014
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-013-1928-2

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