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12-09-2017 | Original Paper | Uitgave 12/2017

Journal of Autism and Developmental Disorders 12/2017

Maternal and Paternal Infertility Disorders and Treatments and Autism Spectrum Disorder: Findings from the Study to Explore Early Development

Tijdschrift:
Journal of Autism and Developmental Disorders > Uitgave 12/2017
Auteurs:
Laura A. Schieve, Carolyn Drews-Botsch, Shericka Harris, Craig Newschaffer, Julie Daniels, Carolyn DiGuiseppi, Lisa A. Croen, Gayle C. Windham
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Electronic supplementary material

The online version of this article (doi:10.​1007/​s10803-017-3283-1) contains supplementary material, which is available to authorized users.

Disclaimer

The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.

Abstract

Previous studies of associations between ASD and conception using assisted reproductive technology (ART) are inconsistent and few studies have examined associations with other infertility treatments or infertility disorders. We examined associations between ASD and maternal/paternal infertility disorders and numerous maternal treatments among 1538 mother–child pairs in the Study to Explore Early Development, a population-based case-control study. ASD was associated with any female infertility diagnosis and several specific diagnoses: blocked tubes, endometriosis, uterine-factor infertility, and polycystic ovarian syndrome. Stratified analyses suggested associations were limited to/much stronger among second or later births. The findings were not explained by sociodemographic factors such as maternal age or education or multiple or preterm birth. ASD was not associated with ART or non-ART infertility treatments.

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Extra materiaal
Supplementary material 1 (DOCX 29 KB)
10803_2017_3283_MOESM1_ESM.docx
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