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16-05-2021

Mapping the Memorial Anxiety Scale for Prostate Cancer to the SF-6D

Auteurs: Daniel O. Erim, Antonia V. Bennett, Bradley N. Gaynes, Ram Sankar Basak, Deborah Usinger, Ronald C. Chen

Gepubliceerd in: Quality of Life Research | Uitgave 10/2021

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Abstract

Purpose

To create a crosswalk that predicts Short Form 6D (SF-6D) utilities from Memorial Anxiety Scale for Prostate Cancer (MAX-PC) scores.

Methods

The data come from prostate cancer patients enrolled in the North Carolina Prostate Cancer Comparative Effectiveness & Survivorship Study (NC ProCESS, N = 1016). Cross-sectional data from 12- to 24-month follow-up were used as estimation and validation datasets, respectively. Participants’ SF-12 scores were used to generate SF-6D utilities in both datasets.
Beta regression mixture models were used to evaluate SF-6D utilities as a function of MAX-PC scores, race, education, marital status, income, employment status, having health insurance, year of cancer diagnosis and clinically significant prostate cancer-related anxiety (PCRA) status in the estimation dataset. Models’ predictive accuracies (using mean absolute error [MAE], root mean squared error [RMSE], Akaike information criterion [AIC] and Bayesian information criterion [BIC]) were examined in both datasets. The model with the highest prediction accuracy and the lowest prediction errors was selected as the crosswalk.

Results

The crosswalk had modest prediction accuracy (MAE = 0.092, RMSE = 0.114, AIC = − 2708 and BIC = − 2595.6), which are comparable to prediction accuracies of other SF-6D crosswalks in the literature. About 24% and 52% of predictions fell within ± 5% and ± 10% of observed SF-6D, respectively. The observed mean disutility associated with acquiring clinically significant PCRA is 0.168 (standard deviation = 0.179).

Conclusion

This study provides a crosswalk that converts MAX-PC scores to SF-6D utilities for economic evaluation of clinically significant PCRA treatment options for prostate cancer survivors.
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Metagegevens
Titel
Mapping the Memorial Anxiety Scale for Prostate Cancer to the SF-6D
Auteurs
Daniel O. Erim
Antonia V. Bennett
Bradley N. Gaynes
Ram Sankar Basak
Deborah Usinger
Ronald C. Chen
Publicatiedatum
16-05-2021
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 10/2021
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-021-02871-9

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