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Research on Child and Adolescent Psychopathology
Gepubliceerd in: Research on Child and Adolescent Psychopathology 8/2022

01-02-2022

Longitudinal Temperament Pathways to ADHD Between Childhood and Adolescence

Auteurs: Michelle M. Martel, Anjeli R. Elkins, Ashley G. Eng, Patrick K. Goh, Pevitr S. Bansal, Tess E. Smith-Thomas, Melina H. Thaxton, Peter Ryabinin, Michael A. Mooney, Hanna C. Gustafsson, Sarah L. Karalunas, Joel T. Nigg

Gepubliceerd in: Research on Child and Adolescent Psychopathology | Uitgave 8/2022

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Abstract

The current investigation extended prior cross-sectional mapping of etiological factors, transdiagnostic effortful and affective traits, and ADHD symptoms to longitudinal pathways extending from two etiological domains: polygenic and prenatal risk. Hypotheses were (1) genetic risk for ADHD would be related to inattentive ADHD symptoms in adolescence and mediated by childhood effortful control; (2) prenatal smoking would be related to hyperactive-impulsive ADHD symptoms during childhood and mediated by childhood surgency; and (3) there would be age-related variation, such that mediation of genetic risk would be larger for older than younger ages, whereas mediation of prenatal risk would be larger in earlier childhood than at later ages. Participants were 849 children drawn from the Oregon ADHD-1000 Cohort, which used a case control sample and an accelerated longitudinal design to track development from childhood (at year 1 ages 7–13) through adolescence (at year 6 ages 13–19). Results showed the mediational pathway from prenatal smoking through surgency to hyperactivity-impulsivity at Year 1 was significant (indirect effect estimate = .053, p < .01). The mediational pathway from polygenic risk through effortful control to inattention at Year 6 was also significant (indirect effect estimate = .084, p < .01). Both results were independent of the association between inattention and hyperactivity-impulsivity and control for the alternative etiological input and held across parent- and teacher-report of ADHD symptoms. In line with dual pathway models of ADHD, early prenatal risk for hyperactivity-impulsivity appears to operate through surgency, while polygenic genetic risk for inattention appears mediated by effortful control.
vorige artikel Is feeling bad good enough? Ethical guilt and callous-unemotional traits in childhood
volgende artikel A New Social Picture Task to Assess Interpretation Bias related to social fears in adolescents
Voetnoten
1
In a path model, a hypothesized bidirectional effect gets two straight arrows, one pointing in each direction. However, models containing bidirectional effects can only be estimated given strong assumptions and other variables (or instruments) that cause each of the two variables involved in the bidirectional effect; therefore, we did not consider them viable here.
 
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Metagegevens
Titel
Longitudinal Temperament Pathways to ADHD Between Childhood and Adolescence
Auteurs
Michelle M. Martel
Anjeli R. Elkins
Ashley G. Eng
Patrick K. Goh
Pevitr S. Bansal
Tess E. Smith-Thomas
Melina H. Thaxton
Peter Ryabinin
Michael A. Mooney
Hanna C. Gustafsson
Sarah L. Karalunas
Joel T. Nigg
Publicatiedatum
01-02-2022
Uitgeverij
Springer US
Gepubliceerd in
Research on Child and Adolescent Psychopathology / Uitgave 8/2022
Print ISSN: 2730-7166
Elektronisch ISSN: 2730-7174
DOI
https://doi.org/10.1007/s10802-022-00902-8

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