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Quality of Life Research
Gepubliceerd in: Quality of Life Research 10/2007

01-12-2007

Long-term health-related quality of life in survivors of meningococcal septic shock in childhood and their parents

Auteurs: Corinne M. P. Buysse, Hein Raat, Jan A. Hazelzet, Lindy C. A. C. Vermunt, Elisabeth M. W. J. Utens, Wim C. J. Hop, Koen F. M. Joosten

Gepubliceerd in: Quality of Life Research | Uitgave 10/2007

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Abstract

Objective

To assess long-term health-related quality of life (HR-QoL) in patients who survived meningococcal septic shock in childhood, and their parents.

Patients and methods

All consecutive patients with meningococcal septic shock requiring intensive care treatment between 1988 and 2001, and their parents. HR-QoL was assessed by the Child Health Questionnaire and the SF-36. Scores were compared with reference data of Dutch general population samples. Lower scores indicated poorer HR-QoL, higher scores more favourable HR-QoL.

Results

One hundred and forty-five patients (response rate 82%) agreed to participate (age PICU admission 3.5 years; follow-up interval 10 years; age follow-up 14.6 years (all medians)). In patients, regardless of age and of patient- versus parent-report, significantly lower scores were found mainly on physical (physical functioning, general health perception) domains and/or physical summary score. In patients <18 years, according to parent-reports, significantly lower scores were also found on psychosocial HR-QoL domains, whereas in patients ≥12 years, according to patients themselves, significantly higher scores were found on psychosocial domains. As to parents themselves, we found significantly higher scores on the majority of HR-QoL scales (both physical and psychosocial).

Conclusions

In patients who survived meningococcal septic shock in childhood significantly lower HR-QoL scores were found on the physical domains. This could indicate that the patient’s disease episode and present health status had a negative impact on their present physical HR-QoL. Overall long-term HR-QoL in parents was significantly higher.
vorige artikel Impact of smoking on asthma symptoms, healthcare resource use, and quality of life outcomes in adults with persistent asthma
volgende artikel The water exercise improves health-related quality of life of frail elderly people at day service facility
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Metagegevens
Titel
Long-term health-related quality of life in survivors of meningococcal septic shock in childhood and their parents
Auteurs
Corinne M. P. Buysse
Hein Raat
Jan A. Hazelzet
Lindy C. A. C. Vermunt
Elisabeth M. W. J. Utens
Wim C. J. Hop
Koen F. M. Joosten
Publicatiedatum
01-12-2007
Uitgeverij
Springer Netherlands
Gepubliceerd in
Quality of Life Research / Uitgave 10/2007
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-007-9271-8

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