JOURNAL TOOLS |
Publishing options |
eTOC |
To subscribe |
Submit an article |
Recommend to your librarian |
ARTICLE TOOLS |
Publication history |
Reprints |
Permissions |
Cite this article as |
Share |
YOUR ACCOUNT
YOUR ORDERS
SHOPPING BASKET
Items: 0
Total amount: € 0,00
HOW TO ORDER
YOUR SUBSCRIPTIONS
YOUR ARTICLES
YOUR EBOOKS
COUPON
ACCESSIBILITY
ORIGINAL ARTICLE Free access
Minerva Urologica e Nefrologica 2017 June;69(3):262-70
DOI: 10.23736/S0393-2249.16.02742-9
Copyright © 2016 EDIZIONI MINERVA MEDICA
language: English
Health related quality of life after radical cystectomy in women: orthotopic neobladder versus ileal loop conduit and impact of incontinence
Mohamed H., ZAHRAN 1, Diaa-Eddin TAHA 2, Ahmed M. HARRAZ 1, Essam M. ZIDAN 3, Mona A. EL-BILSHA 4, Mohamed THARWAT 1, Ahmed S. EL HEFNAWY 1, Bedeir ALI-EL-DEIN 1 ✉
1 Urology Department, Urology and Nephrology Center, Mansoura University, Mansoura, Egypt; 2 Urology Department, Kafr El-Sheikh University, Kafr El-Sheikh, Egypt; 3 Mental Health Department, Faculty of Education, Mansoura University, Mansoura, Egypt; 4 Mental Health Department, Faculty of Nursing, Mansoura University, Mansoura, Egypt
BACKGROUND: Enough data about health related quality of life (HRQOL) after radical cystectomy (RC) and urinary diversion (UD) in women is still lacking. The objectives are to evaluate HRQOL in women after RC and orthotopic neobladder (ONB) versus ileal loop conduit (IC) and to assess the impact of urinary continence.
METHODS: The study included 145 women who underwent RC and came for routine follow-up. HRQOL was assessed by two questionnaires (EORTC-QLQ-C30and FACT-Bl). ONB group was stratified to: totally continent, with nocturnal incontinence (NI) and patients in chronic urinary retention (CUR) and maintained on CIC. The orthotopic group (as a whole and its 3 subgroups) was compared to IC.
RESULTS: ONB group included 22 continent women, 35 with NI and 27 in CUR and on CIC. There were no statistically significant differences between ONB and IC groups in all domains of the two questionnaires. However, continent women showed statistically significant better most of EORTC-QLQ-C30 scales and emotional well-being, functional well-being, bladder cancer subscale and FACT-Bl total Score (P˂0.05) than IC group. Similarly, women in CUR showed statistically significant better global health and physical functioning EORTC-QLQ-C30 scores (P values=0.0001, 0.01) and all domains of FACT-Bl. On the other hand, women with NI showed statistically significant lower values in all domains of the EORTC-QLQ-C30 and FACT-Bl than IC group.
CONCLUSIONS: In women, HRQOL is better after ONB than IC as long as continence status is preserved. If incontinence is expected, IC may be a better option for UD.
KEY WORDS: Urinary diversion - Urinary reservoirs, continent - Urinary bladder neoplasms - Quality of life