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Review of Quality-of-Life Evaluations in Patients with Angina Pectoris

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Abstract

Patients with angina pectoris have a reduced quality of life because of their symptoms, impaired activity and anxiety. However, there is no consensus on the best method of measuring quality of life. A systematic literature search of randomised controlled trials (RCTs) in angina showed that the most common generic questionnaire was the Nottingham Health Profile (NHP) Part 1, and the most common angina-specificmeasure was the Quality-of-Life after AcuteMyocardial Infarction Questionnaire. A comparison of NHP scores with those of the healthy population revealed that patients with angina particularly seem to experience a lack of energy, poor sleep and decreased physical mobility. In the RCTs evaluated, antianginal drugs did not show a significant benefit over placebo in terms of quality of life. As a result of a lack of valid data from RCTs, a strong conclusion regarding the impact of revascularisation procedures on quality of life could not be derived.

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  1. Institute of Health Economics and Clinical Epidemiology, University of Köln, Gleueler Strasse 176-178, 50935, Köln, Germany

    Afschin Gandjour & Karl W. Lauterbach

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Gandjour, A., Lauterbach, K.W. Review of Quality-of-Life Evaluations in Patients with Angina Pectoris. Pharmacoeconomics 16, 141–152 (1999). https://doi.org/10.2165/00019053-199916020-00003

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