Skip to main content
Log in

Prescribing Antibiotics for Impetigo

  • Practical Therapeutics
  • Published:
Drugs Aims and scope Submit manuscript

Summary

Impetigo, a contagious superficial pyogenic infection of the skin, can be treated orally or topically. Nowadays oral erythromycin is the treatment of choice, although flucloxacillin is preferred in areas where the causative micro-organisms are resistant to erythromycin.

Topical mupirocin ointment has shown itself to be as effective as oral therapy in many cases and is less likely to he associated with unwanted effects.

The availability of 2 forms of therapy — oral and topical — means that treatment can be tailored according to the preferences of the patient. Consequently, drug therapy is more likely to be used appropriately. Arguments for and against the prescribing of each form of therapy are presented.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Antibiotic Guidelines. 5th ed., p. 30, Victorian Medical Postgraduate Foundation, Melbourne, 1987

  • Becker LE, Tschen E. Common bacterial infections of the skin. Primary Care 10: 397–409, 1983

    PubMed  CAS  Google Scholar 

  • Carruthers R, Cox GE. Impetigo and its treatment. Medical Journal of Australia 147: 56–57, 1987

    PubMed  CAS  Google Scholar 

  • Casewell MW, Hill RLR. In vitro activity of mupirocin (‘pseudomonic acid’) against clinical isolates of Staphylococcus aureus. Journal of Antimicrobial Chemotherapy 15: 523–531, 1985

    Article  PubMed  CAS  Google Scholar 

  • Casewell MW, Hill RLR. Mupirocin (‘pseudomonic acid’) — a promising new topical antimicrobial agent. Journal of Antimicrobial Chemotherapy 19: 1–5, 1987

    Article  PubMed  CAS  Google Scholar 

  • Dux PH, Fields L, Pollock D. 2% Topical mupirocin versus systemic erythromycin and cloxacillin in primary and secondary skin infections. Current Therapeutic Research 40: 933–940, 1986

    Google Scholar 

  • Editorial. Topical antibiotics. British Medical Journal 1: 1494, 1977

  • Editorial. Recurrent staphylococcal furunculosis. Lancet 2: 81–82, 1985

  • Epstein E. Common skin disorders, p. 110, Medical Economics Company, Oradell, 1979

    Google Scholar 

  • Geronemus RG, Mertz PM, Eaglstein WH. Wound healing. Archives of Dermatology 115: 1311–1314, 1979

    Article  PubMed  CAS  Google Scholar 

  • Goodman AS, Gilman LS. The pharmacological basis of therapeutics, 7th ed., p. 966, Macmillan, New York, 1985

    Google Scholar 

  • Maddin S, Larochelle S, Wilkinson MD, Carey WD, Gratton D, et al. Mupirocin: efficacy and tolerance of a novel, new topical antibiotic vs conventional systemic and topical treatment of primary and secondary skin infections. Contemporary Dermatology 1: 2–7, 1987

    Google Scholar 

  • Maddox JS, Ware JC, Dillon HC. The natural history of streptococcal skin infection: prevention with topical antibiotics. Journal of the American Academy of Dermatology 13: 207–212. 1985

    Article  PubMed  CAS  Google Scholar 

  • Marples RR, Kligman AM. Ecological effects of oral antibiotics on the microflora of human skin. Archives of Dermatology 103: 148–153, 1971

    Article  PubMed  CAS  Google Scholar 

  • Polano MK. Topical skin therapeutics, p. 61. Churchill Livingstone. Edinburgh, 1984

    Google Scholar 

  • Rahman M, Noble WC, Cookson B, Mupirocin-resistant Staphylococcus aureus. Correspondence, Lancet 2: 387, 1987

    Article  Google Scholar 

  • Rogers M, Dorman DC, Gapes M, Ly J. A three-year study of impetigo in Sydney. Medical Journal of Australia 147: 63–65, 1987

    PubMed  CAS  Google Scholar 

  • Ward A, Campoli-Richards DM. Mupirocin: A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs 32: 425–444, 1986

    Article  PubMed  CAS  Google Scholar 

  • Zaynoun ST, Matta MT, Uwayda MM, Kurban AK. Topical antibiotics in pyodermas. British Journal of Dermatology 90: 331–334. 1974

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Carruthers, R. Prescribing Antibiotics for Impetigo. Drugs 36, 364–369 (1988). https://doi.org/10.2165/00003495-198836030-00006

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2165/00003495-198836030-00006

Keywords

Navigation