ABSTRACT

Cluster Randomised Trials discusses the design, conduct, and analysis of health trials that randomise groups of individuals to different treatments. It explores the advantages of cluster randomization, with special attention given to evaluating the effects of interventions against infectious diseases.Avoiding unnecessary mathematical detail, the bo

part |2 pages

Part A

chapter 1|8 pages

Introduction

chapter 2|14 pages

Variability between Clusters

chapter 3|18 pages

Choosing Whether to Randomise by Cluster

part |2 pages

Part B

chapter 4|20 pages

Choice of Clusters

chapter 5|20 pages

Matching and Stratifi cation

chapter 6|20 pages

Randomisation Procedures

chapter 7|24 pages

Sample Size

chapter 8|18 pages

Alternative Study Designs

part |2 pages

Part C

chapter 9|14 pages

Basic Principles of Analysis

chapter 10|36 pages

Analysis Based on Cluster-level Summaries

chapter 12|22 pages

Analysis of Trials with More Complex Designs

part |2 pages

Part D

chapter 13|12 pages

Ethical Considerations

chapter 14|16 pages

Data Monitoring

chapter 15|18 pages

Reporting and Interpretation