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Quality of life is impaired in men with chronic prostatitis

The chronic prostatitis collaborative research network

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Abstract

OBJECTIVE: Health-related quality of life (HRQOL) impairment may be a central component of chronic prostatitis for men afflicted with this condition. Our objective was to examine HRQOL, and factors associated with HRQOL, using both general and condition-specific instruments.

DESIGN: Chronic Prostatis Cohort (CPC) study.

SETTING: Six clinical research centers across the United States and Canada.

PARTICIPANTS: Two hundred seventy-eight men with chronic prostatitis.

MEASUREMENTS AND MAIN RESULTS: The Short Form 12 (SF-12) Mental Component Summary (MCS) and Physical Component Summary (PCS), and the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) were measures used. CPC subjects’ MCS scores (44.0±9.8) were lower than those observed in the most severe subgroups of patients with congestive heart failure and diabetes mellitus, and PCS scores (46.4±9.5) were worse than those among the general U.S. male population. Decreasing scores were seen in both domains with worsening symptom severity (P<.01). History of psychiatric disease and younger age were strongly associated with worse MCS scores, whereas history of rheumatologic disease was associated with worse PCS scores. Predictors of more severe NIH-CPSI scores included lower educational level and lower income; history of rheumatic disease was associated with higher scores.

CONCLUSIONS: Men with chronic prostatitis experience impairment in the mental and physical domains of general HRQOL, as well as condition-specific HRQOL. To optimize the care of men with this condition, clinicians should consider administering HRQOL instruments to their patients to better understand the impact of the condition on patients’ lives.

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Authors and Affiliations

  1. the General Medicine Unit, Medical Services, Massachusetts General Hospital, Boston, Mass

    Mary McNaughton Collins MD, MPH

  2. the Department of Surgery, HMS, Division of Urologic Surgery, Brigham and Women’s Hospital, Boston, Mass

    Michael P. O’Leary MD, MPH

  3. the Department of Urology, Temple University School of Medicine, Philadelphia, Pa

    Michel A. Pontari MD

  4. the Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Medical Center, Philadelphia, Pa

    Jill Santanna MS & J. Richard Landis PhD

  5. the Institute for Health Services and Health Policy Studies, Northwestern University Medical School, Chicago, Ill

    Elizabeth A. Calhoun PhD

  6. the Division of Kidney, Urologic, and Hematologic Diseases, NIH/NIDDK, Bethesda, Md

    John W. Kusek PhD

  7. the Department of Urology and Health Services, University of California, Los Angeles, Calif

    Mark S. Litwin MD, MPH

Authors
  1. Mary McNaughton Collins MD, MPH
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  2. Michel A. Pontari MD
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  3. Michael P. O’Leary MD, MPH
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  4. Elizabeth A. Calhoun PhD
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  5. Jill Santanna MS
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  6. J. Richard Landis PhD
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  7. John W. Kusek PhD
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  8. Mark S. Litwin MD, MPH
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the Chronic Prostatitis Collaborative Research Network

Corresponding author

Correspondence to Mary McNaughton Collins MD, MPH.

Additional information

This work was supported by grants from the NIH/NIDDK (Grant Nos. R01 DK53736, R01 DK53752, R01 DK53732, R01 DK53730, R01 DK53734, and R01 DK53746). Dr. McNaughton Collins is a recipient of a Doris Duke Clinical Scientist Award.

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McNaughton Collins, M., Pontari, M.A., O’Leary, M.P. et al. Quality of life is impaired in men with chronic prostatitis. J GEN INTERN MED 16, 656–662 (2001). https://doi.org/10.1111/j.1525-1497.2001.01223.x

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  • DOI: https://doi.org/10.1111/j.1525-1497.2001.01223.x

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