Journal of the American Academy of Child & Adolescent Psychiatry
ARTICLESProspective Study of Adolescent Drug Use Among Community Samples of ADHD and Non-ADHD Participants
Section snippets
Participants
The data reported here were collected as part of the Minnesota Competence Enhancement Project (MNCEP), a longitudinal study of ADHD that began in 1991. The project identified samples of disruptive and control (nondisruptive) children drawn from 22 suburban elementary schools using a multiple-gate screening procedure (August et al., 1995). A total of 7,231 students in grades 1 through 4 (and ranging in age from 7 to 11 years) were screened. Of these, 318 (ages 7-9) were identified as having
Attrition Analysis
Two sets of attrition analysis were conducted. First, we compared T1 ADHD and control cases who were “ineligible” for a T4 assessment because the family chose to discontinue with the study after the initial assessment and had no T2 and T3 data (ADHD, n = 37; control, n = 28) versus subjects who were “eligible” for a T4 assessment because a T2 and T3 evaluation had been collected and other exclusion criteria were not present (ADHD, n = 138; control, n = 99). Separate one-way ANOVAs (attrition
DISCUSSION
The present prospective longitudinal study found increased rates of drug use among a community-derived sample of children diagnosed with childhood ADHD and followed into the late adolescent years compared with a sample of community controls. These findings were true regardless of whether the drug use outcomes were assessed as categorical or continuous variables. However, increased rates were found only in children in whom ADHD was comorbid with another early-onset externalizing disorder
REFERENCES (45)
- et al.
Persistence and desistance of oppositional defiant disorder in a community sample of children with ADHD
J Am Acad Child Adolesc Psychiatry
(1999) - et al.
The adolescent outcome of hyperactive children diagnosed by research criteria, I: An 8-year prospective follow-up study
J Am Acad Child Adolesc Psychiatry
(1990) - et al.
Is ADHD a risk factor for psychoactive substance use disorders? Findings from a four-year prospective follow-up study
J Am Acad Child Adolesc Psychiatry
(1997) - et al.
Young adult drug use and delinquency: childhood antecedents and adolescent mediators
J Am Acad Child Adolesc Psychiatry
(1996) - et al.
Pathways from ADHD to early drug use
J Am Acad Child Adolesc Psychiatry
(1999) - et al.
ADHD is associated with early initiation of cigarette smoking in children and adolescents
J Am Acad Child Adolesc Psychiatry
(1997) - et al.
Reliability and stability of a semi-structured DSM-IV interview designed for family studies
J Am Acad Child Adolesc Psychiatry
(2003) - et al.
Adolescent substance abuse: a review of the past 10 years
J Am Acad Child Adolesc Psychiatry
(1998) - et al.
Treatment of chronic cocaine abuse and attention deficit disorder, residual type, with magnesium pemoline
Drug Alcohol Depend
(1985) Diagnostic and Statistical Manual of Mental Disorders
(1987)
Diagnostic stability of ADHD in a community sample of school-age children screened for disruptive behavior
J Abnorm Child Psychol
Community-based multi-gate screening procedure of children at-risk for conduct disorder
J Abnorm Child Psychol
Prevalence of ADHD and comorbid disorders among elementary school children screened for disruptive behavior
J Abnorm Child Psychol
A four-year follow-up of hyperactive boys with and without conduct disorder
Br J Psychiatry
Young adult follow-up of hyperactive children: antisocial activities and drug use
J Child Psychol Psychiatry
Psychoactive substance use disorder in adults with attention deficit hyperactivity disorder: effects of ADHD and psychiatric comorbidity
Am J Psychiatry
The impact of peer relationships on aggression in childhood: inhibition through coercion or promotion through peer support
School-based secondary prevention for children with disruptive behavior: initial outcomes
J Abnorm Child Psychol
Which aspects of ADHD are associated with tobacco use in early adolescence
J Child Psychol Psychiatry
Lifetime and Risks: Pathways of Youth in Our Time
Social networks and aggressive behavior: peer support or peer rejection?
Dev Psychol
Psychopathology and substance related problems during early adolescence: a survival analysis
J Clin Child Adolesc Psychol
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Support for this study came from National Institute on Drug Abuse grants DA12995 and K02 DA15347.
Disclosure: Dr. August has financial ties to McNeil Consumer and Specialty Pharmaceuticals. Dr. Realmuto's financial relationships are with McNeil Consumer and Specialty Pharmaceuticals as well as with Shire Pharmaceuticals. The other authors have no financial relationships to disclose.