Journal of the American Academy of Child & Adolescent Psychiatry
ARTICLESA Twin Study of Inattentive, Aggressive, and Anxious/Depressed Behaviors
Section snippets
The Current Research
Responses to CBCL questionnaires on a population-based sample of twins would yield useful data for determining the impact of rc effects on heritability estimates. By attempting to account for rater bias, such an analysis might also demonstrate how the CBCL differs from the DSM for genetic research and, by extension, for clinical use. In this study we computed heritability estimates on parental report for a large group of twins aged 8 to 12 years. We tested models both including and excluding an
Subjects and Procedure
The current research is part of an ongoing project, the Missouri Twin Study. Parents of all twin pairs born in Missouri between 1975 and 1991 are being contacted and invited to participate. Respondents are paid $5 for filling out survey materials, which they complete on their own and then return. In this study we restricted our analyses to reports on same-sex twin pairs, aged 8 to 12 years, for whom both CBCLs had been returned and were filled out completely. Therefore, the current sample is
RESULTS
Because distributions of general population standardized CBCL syndrome scores are skewed, we analyzed raw data for the AP, Agg, and AxD syndromes. We transformed nonnormal distributions to correct skewness and kurtosis. In Table 1, variances are listed on the diagonal of each syndrome within zygosity grouping. Correlations (upper triangle elements, in boldface type) and covariances (lower triangle) between the twins for each syndrome are also reported. As expected, the correlations are stronger
DISCUSSION
In this study we analyzed parental report on the CBCL for same-sex twin pairs aged 8 to 12 years. We fit a series of statistical models to estimate the relative influence of genetic and environmental effects on variability in the AP, Agg, and AxD syndromes. We also included a term to estimate rc-that is, the degree to which systematic biases in parental report might be influencing the statistical models.
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This work was supported by NIMH grant MH52813.