Journal of the American Academy of Child & Adolescent Psychiatry
SPECIAL ARTICLECase Study: Antimanic Effectiveness of Dextroamphetamine in a Brain-Injured Adolescent
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Arousal Regulation in Affective Disorders
2016, Systems Neuroscience in DepressionThe vigilance regulation model of affective disorders and ADHD
2014, Neuroscience and Biobehavioral ReviewsCitation Excerpt :However, according to the model presented here, vigilance stabilising drugs should be able to stop the manic vicious circle. Indeed, when reviewing the literature, there is a lack of empirical evidence for detrimental effects of psychostimulants in mania (Hensch et al., 2010) and even empirical data suggesting the opposite, namely rapid antimanic effects of psychostimulants (Beckmann and Heinemann, 1976; Bschor et al., 2001; Garvey et al., 1987; Max et al., 1995; Schoenknecht et al., 2010). If psychostimulants had a high risk to induce or worsen mania, then the broad use of stimulants in ADHD would be a considerable problem because of the high comorbidity between ADHD and BD: In pediatric samples, comorbidity of BD and ADHD is especially high; up to 85% of children with BD have also been found to have ADHD, and up to 22% of children with ADHD are also diagnosed BD (Singh et al., 2006).
Neuropsychiatry of Pediatric Traumatic Brain Injury
2014, Psychiatric Clinics of North AmericaCitation Excerpt :There may be episodes when the child has intense lability, aggression, hyperactivity, and inattention, and meets criteria for overlapping syndromes of PC, mania or hypomania, and ADHD.9 Mood stabilizers may help and stimulants are not necessarily contraindicated.91 Several reports of stimulants administered to children with TBI who have attention and concentration deficits show positive results, although the data are mixed.92
Bipolar disorder and hyperactivity in adults
2007, EncephaleNew medication strategies for comorbid substance use and bipolar affective disorders
2004, Biological PsychiatryCitation Excerpt :Furthermore, adolescents with BPD might initially seem to have ADHD owing to overlapping symptoms and the more common occurrence of ADHD in this age group (Faraone et al 1997; Geller et al 2000). Psychostimulants are a common pharmacotherapy for ADHD but might be contraindicated in most patients with BPD (Dunn and Kronenberger 2003; Geller and Luby 1997; Max et al 1995). Thus, the implications of stimulant treatment in these patients need consideration.
Combination pharmacotherapy in children and adolescents with bipolar disorder
2003, Biological PsychiatryCitation Excerpt :Yet there are some reports that show this is not always the case in bipolar children and adolescents. Max et al (1995) reported an excellent response to dextroamphetamine in a 14-year-old male with an organic bipolar disorder. Our preliminary data, and those of others, indicate that children and adolescents with bipolar disorders frequently have comorbid ADHD that requires treatment in addition to their bipolar disorder.
The authors thank Robert G. Robinson, M.D., for his helpful comments during manuscript preparation; Yutaka Sato, M.D., and Wilbur Smith, M.D., for interpretation of the neuroimaging; and Samuel Kuperman, M.D., for the graphics.