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Charles A. Alford, Sergio Stagno, Robert F. Pass, William J. Britt, Congenital and Perinatal Cytomegalovirus Infections, Reviews of Infectious Diseases, Volume 12, Issue Supplement_7, September-October 1990, Pages S745–S753, https://doi.org/10.1093/clinids/12.Supplement_7.S745
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Abstract
Cytomegalovirus is the most common cause of congenital and perinatal viral infections throughout the world. Congenital infection occurs in 1% of all live births in developed countries and in an even higher percentage in developing nations. As a result of transmission during birth, by breast milk, and by blood transfusions, perinatal infections are much more prevalent than congenital infections. The vast majority of these infections are chronic, subclinical forms, but symptomatic infections are sufficiently prevalent and dangerous to represent a major unsolved public health problem throughout the world. In this review the epidemiologic, clinical, immunologic, and therapeutic facets of cytomegaloviral infections in pregnant women and their offspring will be discussed.
- pregnancy
- blood transfusion
- developed countries
- developing countries
- milk, human
- virus diseases
- infections
- cytomegalovirus infections
- cytomegalovirus
- public health medicine
- congenital cytomegalovirus infection
- live birth
- perinatal infections
- perinatal period
- immunology
- offspring
- congenital infections
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