Ageing in the musculoskeletal system

Authors

  • Sally Roberts
  • Pauline Colombier
  • Aneka Sowman
  • Claire Mennan
  • Jan H D Rölfing
  • Jérôme Guicheux
  • James R Edwards

DOI:

https://doi.org/10.1080/17453674.2016.1244750

Abstract

ABSTRACT The extent of ageing in the musculoskeletal system during the life course affects the quality and length of life. Loss of bone, degraded articular cartilage, and degenerate, narrowed intervertebral discs are primary features of an ageing skeleton, and together they contribute to pain and loss of mobility. This review covers the cellular constituents that make up some key components of the musculoskeletal system and summarizes discussion from the 2015 Aarhus Regenerative Orthopaedic Symposium (AROS) (Regeneration in the Ageing Population) about how each particular cell type alters within the ageing skeletal microenvironment.

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Published

2016-12-16

How to Cite

Roberts, S., Colombier, P., Sowman, A., Mennan, C., Rölfing, J. H. D., Guicheux, J., & Edwards, J. R. (2016). Ageing in the musculoskeletal system. Acta Orthopaedica, 87(sup363), 15–25. https://doi.org/10.1080/17453674.2016.1244750

Issue

Acta Orthopaedica, Volume 87, Supplement 363 (2016)

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License.

Acta Orthopaedica (Scandinavica) content is available freely online as from volume 1, 1930. The journal owner owns the copyright for all material published until volume 80, 2009. As of June 2009, the journal has however been published fully Open Access, meaning the authors retain copyright to their work. As of June 2009, articles have been published under CC-BY-NC or CC-BY licenses, unless otherwise specified.
 
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