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Pharmacopsychiatry 2004; 37: 103-112
DOI: 10.1055/s-2004-832663
General Concepts
© Georg Thieme Verlag KG Stuttgart · New York

The Etiopathogenesis of Schizophrenias

J. Kornhuber1 , J. Wiltfang1 , S. Bleich1
  • 1Klinik mit Poliklinik für Psychiatrie und Psychotherapie, Friedrich-Alexander Universität zu Erlangen-Nürnberg, Erlangen, Germany
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Publication History

Publication Date:
16 November 2004 (online)

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There is no generally accepted model explaining the aetiopathogenesis of schizophrenias. In recent years, hypotheses with a focus on single aspects of neurotransmission, single major genetic loci or single brain areas were predominating. Now, these different approaches converge to systemic models including neurotransmission, genetic changes and neurodevelopmental malformation of brain structures. Such systemic models will explain more aspects of schizophrenias than the recent confined hypotheses.

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Prof. Dr. med. Johannes Kornhuber

Friedrich-Alexander Universität zu Erlangen-Nürnberg

Klinik mit Poliklinik für Psychiatrie und Psychotherapie

Schwabachanlage 6-10

91054 Erlangen

Phone: +49 9131 85 34160

Fax: +9131 85 34862

Email: Johannes.Kornhuber@psych.imed.uni-erlangen.de

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