Am J Perinatol 2003; 20(2): 059-062
DOI: 10.1055/s-2003-38320
Copyright © 2003 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Gastrointestinal Malformations in Two Infants Born to Women with Hyperthyroidism Untreated in the First Trimester

Muhieddine Seoud1 , Anwar Nassar1 , Ihab Usta1 , Mohammad Mansour1 , Ibrahim Salti2 , Khaled Younes3
  • 1Obstetrics and Gynecology, The American University of Beirut Medical Center, New York, New York
  • 2Internal Medicine, The American University of Beirut Medical Center, New York, New York
  • 3Pediatrics, The American University of Beirut Medical Center, New York, New York
Further Information

Publication History

Publication Date:
27 March 2003 (online)

ABSTRACT

We report two infants with gastrointestinal anomalies: one with esophageal atresia and tracheo-esophageal fistula and the other with biliary tree atresia, born to hyperthyroid women diagnosed and treated with methimazole after 14 weeks' gestation. Euthyroidism was documented in both infants. These cases raise the issue of whether untreated hyperthyroidism and not methimazole intake is the teratogen.

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