Case ReportsCentral odontogenic fibroma granular cell variant: A case report and review of the literature☆
Section snippets
Report of a case
In September 1997, a 61-year-old man came to the emergency department of our hospital, complaining of an abscess of the anterior palate of 10 days' of duration. The patient smoked 2 cigars per day and drank about 90 g of ethanol per day.
The abscess was drained. An orthopantomograph (Fig 1) revealed a large radiolucency affecting the anterior maxilla and significant resorption of the roots of the anterior teeth.
Discussion
Clinical features of 22 previously reported cases6, 7, 8, 9, 10, 11, 12 of central OF, granular cell variant, include 17 located in the mandible, 4 in the maxilla, and 1 in an unreported location. Of these, 17 were confined to the posterior segments (premolar-molar region), 4 to the canine region, and none to the incisors. The mean age of incidence is 46.8 years, with a range between 16 and 77 years. There is a distinct female predilection. Only 3 references include the size of the lesion: 15 ×
References (21)
The central odontogenic fibroma: An attempt at clarification
Oral Surg Oral Med Oral Pathol
(1980)- et al.
A central odontogenic fibroma exhibiting pleomorphic fibroblasts and numerous calcifications
Br J Oral Maxillofac Surg
(1991) - et al.
Granular-cell ameloblastic fibroma: Report of two cases
Oral Surg Oral Med Oral Pathol
(1963) - et al.
Central granular-cell tumor of the jaws (the so-called granular-cell ameloblastic fibroma)
Oral Surg Oral Med Oral Pathol
(1978) - et al.
Central odontogenic fibroma, granular cell variant
Oral Surg Oral Med Oral Pathol
(1989) - et al.
Granular cell lesions of the jaws and oral cavity: A clinicopathologic, immunohistochemical and ultrastructural study
J Oral Maxillofac Surg
(1989) Central granular cell tumor of the jaw: An electron microscopic and immunohistochemical study
Oral Surg Oral Med Oral Pathol
(1991)- et al.
Central odontogenic granular cell tumor of the jaw: Report of case and immunohistochemical and electron microscopic study
J Oral Maxillofac Surg
(1995) - et al.
Central odontogenic fibroma: Clinicopathologic features of 19 cases and review of the literature
J Oral Maxillofac Surg
(1991) - et al.
Radiologic features of central odontogenic fibroma
Oral Surg Oral Med Oral Pathol
(1994)
Cited by (26)
Central Granular Cell Odontogenic Tumor: A Literature Review of Cases Reported in the Last 71 Years with a New Case Report
2023, Chinese Medical Sciences JournalCentral odontogenic fibroma: An updated systematic review of cases reported in the literature with emphasis on recurrence influencing factors
2018, Journal of Cranio-Maxillofacial SurgeryCitation Excerpt :The follow-up information, after a period of about 3 years, indicates that this type of tumour has a benign behaviour due to its clinical and radiographic aspects. In addition, it has been shown that WHO-type COF has no tendency for infiltrative growth or relapse (Doyle et al., 1985; Handlers et al., 1991; Calvo et al., 2002; Baser et al., 2014). According to analysis of the data referring to recurrence, it was observed that the maxilla presents a greater rate of recurrence than the mandible (de Matos et al., 2011; Melo et al., 2011; Wu et al., 2013; Baser et al., 2014; Salgado et al., 2014).
Granular cell tumour developing in the background of a previous mandibular giant cell lesion: Case report
2016, International Journal of Surgery Case ReportsCentral granular cell odontogenic tumor of mandible: A case report
2013, Journal of Oral and Maxillofacial Surgery, Medicine, and PathologyOdontogenic Cysts and Tumors
2011, Surgical Pathology ClinicsCitation Excerpt :In one study, the presence of budding hyperplasia of the overlying surface epithelium was associated with an increased recurrence rate.135 The central granular cell odontogenic tumor is a rare odontogenic neoplasm, with only 35 cases reported in the literature.138–143 This tumor also has been referred to as granular cell ameloblastic fibroma, central granular cell odontogenic fibroma, and central granular cell tumor of the jaws.
Central odontogenic fibroma with features of central granular cell odontogenic tumor
2010, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology
- ☆
Address correspondence and reprint requests to Dr Calvo: Department of OMFS, Hospital de León, Altos de Nava s/n 24008, León, Spain; e-mail: [email protected]