Original articleThe Relationship Between Cerebral Oxygen Saturation Changes and Postoperative Cognitive Dysfunction in Elderly Patients After Coronary Artery Bypass Graft Surgery
Section snippets
Methods
After approval by the institutional review board and after obtaining written informed consent, 76 patients at least 65 years of age undergoing CABG surgery were recruited between January 2006 and September 2008 at a tertiary care hospital.
Inclusion criteria were as follows: (1) scheduled for a primary CABG surgery, (2) 65 years of age or older, and (3) able to speak and read French. Exclusion criteria were as follows: (1) Mini-Mental State Examination (MMSE) score <24 before surgery, (2)
Results
The clinical and demographic characteristics of the 61 patients and the comparison between CABG surgery with and without CPB are presented in Table 1. Both with and without CPB groups were comparable for each preoperative variable except for hypertension. The CABG surgery without CPB group showed a higher incidence of hypertension.
The majority of patients (n = 45) were recruited a day before surgery. The others were recruited at the preadmission clinic (n = 16) (ie, 27 ± 24 days before surgery),
Discussion
POCD after cardiac surgery is a frequently reported complication affecting patients' postoperative outcomes. The etiology of POCD can be multifactorial; the most commonly cited etiologies being embolism and hypoperfusion related to CPB, which affect the cerebral oxygen supply-demand balance.46 Among the neurologic monitoring techniques available to detect a cerebral oxygen supply-demand imbalance during cardiac surgery, NIRS allows the continuous and noninvasive monitoring of rSO2 and provides
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Cited by (0)
Supported by the Montreal Heart Institute Foundation.