Abstract
Abstract Event-related potentials were recorded (N = 18) in a hybrid go/no-go Eriksen flanker task to study the neural correlates of response inhibition. Three letters were assigned to either a left-hand, a right-hand, or a no-go response. These three letters appeared either as targets signaling the assigned response or as flankers surrounding the target. The lateralized readiness potentials revealed erroneous cortical response priming on go trials, in which the target and flankers were assigned to different hands, as well as on no-go trials, in which the flankers primed one of the two hands. Exactly these two conditions were accompanied by a fronto-central amplitude modulation of the N200, suggesting that this ERP component may reflect inhibitory executive functions. The data replicate and extend recent studies by Kopp, Rist, and Mattler (1996) and Kopp, Mattler, Goertz, and Rist (1996).
References
Baddeley, A.D. (1986). Working memory . Oxford: Clarendon Press .Bench, C.J. , Frith, C.D. , Grasby, P.M. , Friston, K.J. , Paulesu, E. , Frackowiak, R.S.J. , Dolan, R.J. (1993). Investigations of the functional anatomy of attention using the Stroop test. Neuropsychologia, 31, 907– 922 .Coles, M.G.H. (1989). Modern mind-brain reading: Psychophysiology, physiology, and cognition. Psychophysiology, 26, 251– 269 .Dagenbach, D. , Carr, T.H. (1994). Inhibitory processes in attention, memory and language . San Diego, CA: Academic Press .Eimer, M. (1993). Effects of attention and stimulus probability on ERPs in a go/no-go task. Biological Psychology, 35, 123– 138 .Eriksen, B.A. , Eriksen, C.W. (1974). Effects of noise letters upon the identification of a target letter in a nonsearch task. Perception & Psychophysics, 16, 143– 149 .Falkenstein, M. , Hoormann, J. , Hohnsbein, J. (1999). ERP components in go/no-go tasks and their relation to inhibition. Acta Psychologica, 101, 267– 291 .Falkenstein, M. , Hohnsbein, J. , Hoormann, J. , Blanke, L. (1991). Effects of crossmodal divided attention on late ERP components. II. Error processing in choice reaction tasks. Electroencephalography and Clinical Neurophysiology, 78, 447– 455 .Falkenstein, M. , Koshlykova, N.A. , Kiroj, V.N. , Hoormann, J. , Hohnsbein, J. (1995). Late ERP components in visual and auditory Go/No-go tasks. Electroencephalography and Clinical Neurophysiology, 96, 36– 43 .Fuster, J.M. (1997). The prefrontal cortex: Anatomy, physiology, and neuropsychology of the frontal lobe (3rd ed.). New York: Raven Press .Gratton, G. , Coles, M.G.H. , Sirevaag, E.J. , Eriksen, C.W. , Donchin, E. (1988). Pre- and poststimulus activation of response channels: A psychophysiological analysis. Journal of Experimental Psychology: Human Perception and Performance, 14, 331– 344 .Heil, M. , Bajric, J. , Rösler, F. , Hennighausen, E. (1996). Event-related potentials during mental rotation: Disentangling the contributions of character classification and image transformation. Journal of Psychophysiology, 10, 326– 335 .Heil, M. , Wahl, K. , Herbst, M. (1999). Mental rotation, memory scanning, and the central bottleneck. Psychological Research, 62, 48– 61 .Hennighausen, E. , Heil, M. , Rösler, F. (1993). A correction method for DC-drift artifacts. Electroencephalography and Clinical Neurophysiology, 86, 199– 204 .Huynh, H. , Feldt, L.S. (1976). Estimation of the Box correction for degrees of freedom from sample data in randomized block and splitplot designs. Journal of Education Statistics, 1, 69– 82 .Jodo, E. , Kayama, Y. (1992). Relation of a negative ERP component to response inhibition in a go / no-go task. Electroencephalography and clinical Neurophysiology, 82, 477– 482 .Kok, A. (1986). Effects of degradation of visual stimuli on components of the event-related potential (ERP) in go/no-go reaction tasks. Biological Psychology, 23, 21– 38 .Konishi, S. , Nakajima, K. , Uchida, I. , Kikyo, H. , Kameyama, M. , Kiyashita, Y. (1999). Common inhibitory mechanism in human inferior prefrontal cortex revealed by event-related functional MRI. Brain, 122, 981– 991 .Kopp, B. , Mattler, U. , Goertz, R. , Rist, F. (1996a). N2, P3, and the lateralized readiness potential in a no-go task involving selective response priming. Electroencephalography and Clinical Neurophysiology, 99, 19– 27 .Kopp, B. , Rist, F. , Mattler, U. (1996b). N200 in the flanker task as a neurobehavioral tool for investigating executive control. Psychophysiology, 33, 282– 294 .Larrue, V. , Celsis, P. , Bes, A. , Marc-Vergnes, J.P. (1994). The functional anatomy of attention in humans: Cerebral blood flow changes induced by reading, naming, and the Stroop effect. Journal of Cerebral Blood Flow and Metabolism, 14, 958– 962 .Miller, J. (1987). Priming is not necessary for selective-attention failures: Semantic effects of unattended, unprimed letters. Perception & Psychophysics, 41, 419– 434 .Miller, J. , Patterson, T. , Ulrich, R. (1998). Jackknife-based method for measuring LRP onset latency differences. Psychophysiology, 35, 99– 115 .Perret, E. (1974). The left frontal lobe in man and the suppression of habitual responses in verbal categorical behavior. Neuropsychologia, 12, 323– 330 .Pfefferbaum, A. , Ford, J.M. , Weller, B.J. , Kopell, B.S. (1985). ERPs to response production and inhibition. Electroencephalography and Clinical Neurophysiology, 60, 423– 434 .Reeve, T.G. , Proctor, R.W. (1990). The salient-features coding principle for spatial- and symbolic-compatibility effects. In R. W. Proctor & T. G. Reeve (Eds.), Stimulus-response compatibility (pp. 163-180). Amsterdam: Elsevier .Roberts, R.J. , Pennington, B.F. (1996). An interactive framework for examining prefrontal cognitive processes. Developmental Neuropsychology, 12, 105– 126 .Sasaki, K. , Gemba, H. (1986). Electrical activity in the prefrontal cortex specific to no-go reaction of conditioned hand movement with color discrimination in the monkey. Experimental Brain Research, 64, 603– 606 .Sasaki, K. , Gemba, H. , Tsujimoto, T. (1989). Suppression of visually initiated hand movement by stimulation of the prefrontal cortex in the monkey. Brain Research, 495, 100– 107 .Schröger, E. (1993). Event-related potentials to auditory stimuli following transient shifts of spatial attention in a go/no-go task. Biological Psychology, 36, 183– 207 .Shallice, T. (1988). From neuropsychology to mental structure . Cambridge: Cambridge University Press .Smid, H.G.O.M. , Mulder, G. , Mulder, L.J.M. (1990). Selective response activation can begin before stimulus recognition is complete: A psychophysiological and error analysis of continuous flow. Acta Psychologica, 74, 169– 201 .
