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Originalia

Das ALS-Depressionsinventar (ADI):

Published Online:September 01, 2006https://doi.org/10.1026/1616-3443.34.1.19

Abstract

Zusammenfassung.Theoretischer Hintergrund: Bei der amyotrophen Lateralsklerose (ALS) handelt es sich um eine fortschreitende degenerative Erkrankung, die zu vollständigem motorischen Funktionsausfall führen kann. Depressive Stimmung bei ALS-Patienten wirkt sich verkürzend auf die verbleibende Lebensspanne aus. Zur quantitativen Erfassung von Depression bei ALS-Patienten werden Fragebögen verwendet, die die spezifische Situation der zunehmenden körperlichen Beeinträchtigung bis hin zur vollständigen Lähmung und künstlicher Ernährung und Beatmung nicht berücksichtigen. Fragestellung: Die Entwicklung eines speziell auf diese Patientengruppe ausgerichteten Inventars zur Messung depressiver Symptomatik. Methode: Das neu entworfene Inventar wurde gesunden Personen (93), ALS-Patienten (76) und depressiven Patienten (56) vorgelegt. Anhand der Ergebnisse wurde das ursprüngliche Inventar auf 12 Items reduziert (ADI-12). Ergebnis: 75% der ALS-Patienten wiesen depressive Symptome auf. Patienten mit ALS waren signifikant weniger depressiv als Patienten mit Depression. Schlussfolgerungen: Bei ALS-Patienten ist mit depressiver Verstimmung zu rechnen. Mit dem ADI-12 kann Depression auch noch bei schwerstbeeinträchtigten ALS-Patienten gemessen werden.


The ALS Depression Inventory (ADI): A questionnaire to assess depression in patients with neurodegenerative dieases (amyotropic lateral sclerosis)

Abstract.Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease which leads to complete motor paralysis. Depressive mood shortens survival time in ALS patients. Thus far depression in ALS patients has been measured quantitatively using inventories that do not take into account the specific situation of increasing physical impairment culminating in total motor paralysis, artificial feeding, and ventilation. Objective: The development of an inventory to assess depressive symptoms in such patients. Methods: Healthy participants (96), ALS patients (76), and patients with a depressive disorder (56) were presented with a newly designed inventory. On the basis of the results obtained the inventory was reduced to 12 items (ADI-12). Results: Depressive symptoms were found in 75% of the ALS patients. ALS patients were significantly less depressed than patients with a depressive disorder. Conclusions: Depressive symptoms occur in ALS patients. The ADI-12 measures depressive symptoms in severly paralyzed patients.

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