Abstract
We investigated the efficacy of prophylactic use of single dose oral ofloxacin and trimethoprim-sulfamethoxazole regimens for transrectal prostate biopsy in 110 men. In the ofloxacin, trimethoprim-sulfamethoxazole and control groups, urinary infection was found in 2 (4.76%), 3 (6.66%) and 6 (26.08%) patients, respectively. Both of these antibiotic regimens produced a statistically significant reduction in urinary infection (p<0.02, p<0.05).
Our study indicates that single dose fluoroquinolone or trimethoprimsulfamethoxazole prophylaxis seems to be effective, practical and economical.
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Isen, K., Küpeli, B., Sinik, Z. et al. Antibiotic Prophylaxis for Transrectal Biopsy of the Prostate: A Prospective Randomized Study of the Prophylactic Use of Single Dose Oral Fluoroquinolone Versus Trimethoprim-Sulfamethoxazole. Int Urol Nephrol 31, 491–495 (1999). https://doi.org/10.1023/A:1007115312039
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DOI: https://doi.org/10.1023/A:1007115312039