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Follow-up 10 years later of 34 Klinefelter males with karyotype 47,XXY and 16 hypogonadal males with karyotype 46,XY

Published online by Cambridge University Press:  09 July 2009

Johannes Nielsen ,
Svend G. Johnsen  and
Kurt Sørensen
Johannes Nielsen*
Affiliation:
Cytogenetic Laboratory, Århus Psychiatric Hospital, Risskov, Denmark; Male Hypogonadism Study Section, Medical Department P, Rigshospitalet, Copenhagen, Denmark
Svend G. Johnsen
Affiliation:
Cytogenetic Laboratory, Århus Psychiatric Hospital, Risskov, Denmark; Male Hypogonadism Study Section, Medical Department P, Rigshospitalet, Copenhagen, Denmark
Kurt Sørensen
Affiliation:
Cytogenetic Laboratory, Århus Psychiatric Hospital, Risskov, Denmark; Male Hypogonadism Study Section, Medical Department P, Rigshospitalet, Copenhagen, Denmark
*
1Address for correspondence: Dr Johannes Nielsen, Cytogenetic Laboratory, Århus Psychiatric Hospital, DK-8240 Risskov, Denmark.
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Synopsis

A 10-year follow-up study is reported of 50 hypogonadal males, 34 of whom had the karyotype 47,XXY and 16 karyotype 46,XY. The social class of the former group was significantly lower and the frequency of criminal behaviour higher when compared with the latter group and the Danish male population. The frequency of mental illness was higher in the Klinefelter males with karyotype 47,XXY than in the remainder. The aetiology and pathogenesis of deviant mental development in the patient population and various aspects of their treatment are discussed.

Type
Research Article
Information
Psychological Medicine , Volume 10 , Issue 2 , May 1980 , pp. 345 - 352
Copyright
Copyright © Cambridge University Press 1980

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