OncologyMorbidity and Quality of Life in Elderly Patients Receiving Ileal Conduit or Orthotopic Neobladder After Radical Cystectomy for Invasive Bladder Cancer
Section snippets
Study Design
The charts of 105 bladder cancer patients 75 years or older undergone radical cystectomy, followed by an ileal conduit or an orthotopic bladder substitution at 3 Italian institutions between January 2000 and October 2004 were reviewed. Eighty-five patients (53 ileal conduit and 32 bladder substitution, median age 78, range 75 to 88 years) of whom all preoperative (including American Society of Anesthesiologists [ASA] score) and follow-up information were available, entered the study, whereas
Results
Median age (range) was 77.5 years (75 to 82 years) in the neobladder group and 78.9 years (75 to 88 years) in the ileal conduit group (P = 0.03). No significant difference emerged in the clinical staging and gender distribution among patients in the 2 groups, whereas there was a significantly higher proportion of ASA scores17 III and IV in the group of patients receiving an ileal conduit. Table 1 reports the comparative data of the most relevant intraoperative and perioperative variables. No
Comment
Recent reports have shown that radical cystectomy can be safely performed in elderly individuals with low perioperative mortality, acceptable morbidity and in most cases without significant deviations from routine postoperative care.18, 19, 20 An ileal conduit is usually the urine diversion of choice in elderly patients.18 The feasibility of an orthotopic neobladder has been reported in 22 patients with no additional complications compared with an ileal conduit.11 However, comparative data in
Conclusions
In our retrospective analysis, elderly patients receiving bladder substitution showed no difference in survival or severe complications when compared with a group of patients of similar age who had an ileal conduit. Similarly, no significant differences in QoL outcomes could be detected.
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Quality of life after definitive treatment for bladder cancer: A systematic review and meta-analysis
2024, Radiotherapy and OncologyMidterm Health-related Quality of Life After Radical Cystectomy: A Propensity Score–matched Analysis
2020, European Urology FocusCitation Excerpt :First, we used the EORTC QLQ-C30, which is, unlike the EORTC QLQ-BLM30, not a bladder cancer–specific questionnaire and lacks additional information regarding body image, urostomy problems, and use of catheters. The QLQ-BLM30 has been used in several publications before, but is not validated [17–19]. Recently, the bladder-specific Bladder Utility Symptom Scale has been introduced, but has not been externally validated yet [20].
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