Adult urologyImpact of superficial bladder cancer and transurethral resection on general health-related quality of life: An SF-36 survey
Section snippets
Material and methods
From November 2000 to December 2003, 253 patients underwent a total of 403 TURs at our institution. Of these patients and TURs, those with benign tumors or invasive or metastatic bladder cancer requiring radical or palliative treatment other than TUR and those with prior nephroureterectomy or other treatment for upper urinary tract cancer were excluded from this study. Furthermore, patients older than 80 years were also excluded because of a lack of data in the SF-36 of Japanese normal
Results
The patient demographics are summarized in Table I. Of the 178 TURs enrolled in this study, 93 were the first procedure for primary tumors, 34 were the second, 17 were the third, and 34 were the fourth or later. Although no sex differences were found among the four groups, the patients who underwent the third or later TURs were older than those undergoing the first or second TURs (66.0 ± 9.7 years versus 70.1 ± 9.8 years, P = 0.008). No significant differences were found in the period from
Comment
Many studies have reported on the GHQOL of patients with bladder cancer.1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 However, most of these dealt with postcystectomy status for invasive bladder cancer. It was reported in many studies that the type of urinary diversion did not affect GHQOL,3, 4, 6, 8, 10 but some reports suggested marginal9 or significant superiority of orthotopic neobladder or continent urinary diversion compared with ileal conduit in several domains.5, 7, 11 Although Fujisawa et al.6
Conclusions
In patients with superficial bladder cancer, the GH perception could be severely impaired throughout follow-up. Mental health was impaired most severely at the first TUR, and physical functioning, RP, role-emotional, and social function at the second or third TUR. Except for the GH perception, the scores of these domains returned to normal levels if patients underwent four or more TURs. Urologists should be aware of the considerable impact of superficial bladder cancer on the GHQOL of these
Acknowledgment
To Drs. Hiroki Ohara, Nobufimi Ueda, and Naoki Terada for their cooperation in this study.
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Cited by (52)
Supportive Care Needs of Patients on Surveillance and Treatment for Non-Muscle-Invasive Bladder Cancer
2021, Seminars in Oncology NursingCitation Excerpt :A recent literature review of the mental health implications of bladder cancer included only two studies that exclusively focused on patients with NMIBC (both were prospective observational studies with a total of 521 patients sampled) and six studies including both patients with MIBC and patients with NMIBC.50 Both NMIBC-dedicated studies reported that mental health was significantly negatively affected at time of diagnosis51 and particularly after a first TURBT.52 Similarly, a synthesis of qualitative studies focused on patients’ experiences of a bladder cancer diagnosis included only two studies exploring patients’ experience of NMIBC with symptoms associated with BCG treatments and TURBT surgeries described as “short lived”.53
Effects of Bladder Cancer on UK Healthcare Costs and Patient Health-Related Quality of Life: Evidence From the BOXIT Trial
2020, Clinical Genitourinary CancerMental health implications in bladder cancer patients: A review
2019, Urologic Oncology: Seminars and Original InvestigationsCitation Excerpt :Conversely, Smith et al. showed that most physical, mental, and social health-related QOL domains remained low over 1 year after diagnosis of bladder cancer [22]. While some studies describe a return to baseline mental health over time, long-term studies of lasting psychological changes have yet to be investigated in this patient population to date [11–13,16,18,24]. There is inconclusive data regarding mental health differences in bladder cancer patients across age, gender, race, and disease stage [22–25].